{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T14:04:18Z","timestamp":1788271458625,"version":"build-2803163510"},"reference-count":35,"publisher":"Center for Academic Publications Japan","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Nutritional Science and Vitaminology, J Nutr Sci Vitaminol","J Nutr Sci Vitaminol","JNSV"],"published-print":{"date-parts":[[2016]]},"DOI":"10.3177\/jnsv.62.330","type":"journal-article","created":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T22:07:54Z","timestamp":1480975674000},"page":"330-334","source":"Crossref","is-referenced-by-count":4,"title":["Effect of Long-Term Proton Pump Inhibitor Therapy on Nutritional Status in Elderly Hospitalized Patients"],"prefix":"10.3177","volume":"62","author":[{"given":"Mariko","family":"NAKAMICHI","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Haradoi Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidetaka","family":"WAKABAYASHI","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Yokohama City University Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1759","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Durand C, Willett KC, Desilets AR. 2012. Proton pump inhibitor use in hospitalized patients: is overutilization becoming a problem? Clin Med Insights Gastroenterol 5: 65-76.","DOI":"10.4137\/CGast.S9588"},{"key":"2","unstructured":"2) Sugano K. 2007. Proton pump inhibitor in the management of acid-related disorders in Japan: history and perspective. Nihon Rinsho 65: 2375-2381 (in Japanese)."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Haastrup P, Paulsen MS, Begtrup LM, Hansen JM, Jarbøl DE. 2014. Strategies for discontinuation of proton pump inhibitors: a systematic review. Fam Pract 31: 625-630.","DOI":"10.1093\/fampra\/cmu050"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) McCarthy DM. 2010. Adverse effects of proton pump inhibitor drugs: clues and conclusions. Curr Opin Gastroenterol 26: 624-631.","DOI":"10.1097\/MOG.0b013e32833ea9d9"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Dial S, Alrasadi K, Manoukian C, Huang A, Menzies D. 2004. Risk of Clostridium difficile diarrhea among hospital inpatients prescribed proton pump inhibitors: cohort and case-control studies. CMAJ 171: 33-38.","DOI":"10.1503\/cmaj.1040876"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Gulmez SE, Holm A, Frederiksen H, Jensen TG, Hallas J. 2007. Use of proton pump inhibitors and the risk of community-acquired pneumonia: a population-based case-control study. Arch Intern Med 167: 950-955.","DOI":"10.1001\/archinte.167.9.950"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Yang YX, Lewis JD, Epstein S, Metz DC. 2006. Long-term proton pump inhibitor therapy and risk of hip fracture. JAMA 296: 2947-2953.","DOI":"10.1001\/jama.296.24.2947"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Ito T, Jensen RT. 2010. Association of long-term proton pump inhibitor therapy with bone fractures and effects on absorption of calcium, vitamin B12, iron, and magnesium. Curr Gastroenterol Rep 12: 448-457.","DOI":"10.1007\/s11894-010-0141-0"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Chia CT, Lim WP, Vu CK. 2014. Inappropriate use of proton pump inhibitors in a local setting. Singapore Med J 55: 363-366.","DOI":"10.11622\/smedj.2014087"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Ladd AM, Panagopoulos G, Cohen J, Mar N, Graham R. 2014. Potential costs of inappropriate use of proton pump inhibitors. Am J Med Sci 347: 446-451.","DOI":"10.1097\/MAJ.0b013e31829f87d5"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Tan JL, Eastment JG, Poudel A, Hubbard RE. 2015. Age-related changes in hepatic function: An update on implications for drug therapy. Drugs Aging 32: 999-1008.","DOI":"10.1007\/s40266-015-0318-1"},{"key":"12","unstructured":"12) Guyonnet S, Secher M, Vellas B. 2015. Nutrition, frailty, cognitive frailty and prevention of disabilities with aging. Nestle Nutr Inst Workshop Ser 82: 143-152."},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Seiler WO. 2001. Clinical pictures of malnutrition in ill elderly subjects. Nutrition 17: 496-498.","DOI":"10.1016\/S0899-9007(01)00558-5"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Wakabayashi H, Sakuma K. 2014. Rehabilitation nutrition for sarcopenia with disability: a combination of both rehabilitation and nutrition care management. J Cachexia Sarcopenia Muscle 5: 269-277.","DOI":"10.1007\/s13539-014-0162-x"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Zadak Z, Hyspler R, Ticha A, Vlcek J. 2013. Polypharmacy and malnutrition. Curr Opin Clin Nutr Metab Care 16: 50-55.","DOI":"10.1097\/MCO.0b013e32835b612e"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Boban M, Persic V, Petricevic M, Biocina B, Sipic T, Pehar-Pejcnovic V, Balen S, Zulj M, Vcev A. 2016. Connections of nutritional status and proton pump inhibitor therapy in patients scheduled for cardiovascular rehabilitation after treatment for ischemic and valvular heart disease. Kardiol Pol 74: 461-468.","DOI":"10.5603\/KP.a2015.0197"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Czwornog JL, Austin GL. 2015. Association of proton pump inhibitor (PPI) use with energy intake, physical activity, and weight gain. Nutrients 7: 8592-8601.","DOI":"10.3390\/nu7105416"},{"key":"18","unstructured":"18) Vellas B, Villars H, Abellan G, Soto ME, Rolland Y, Guigoz Y, Morley JE, Chumlea W, Salva A, Rubenstein LZ, Garry P. 2006. Overview of the MNA—its history and challenges. J Nutr Health Aging 10: 456-465."},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Rubenstein LZ, Harker JO, Salva A, Guigoz Y, Vellas B. 2001. Screening for undernutrition in geriatric practice: developing the Short-Form Mini Nutritional Assessment (MNA-SF). J Gerontol A Biol Sci Med Sci 56: M366-M372.","DOI":"10.1093\/gerona\/56.6.M366"},{"key":"20","unstructured":"20) Guigoz Y. 2006. The Mini-Nutritional Assessment (MNA) review of the literature—What does it tell us? J Nutr Health Aging 10: 466-487."},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Crary MA, Mann GD, Groher ME. 2005. Initial psychometric assessment of a functional oral intake scale for dysphagia in stroke patients. Arch Phys Med Rehabil 86: 1516-1520.","DOI":"10.1016\/j.apmr.2004.11.049"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Ottenbacher KJ, Hsu Y, Granger CV, Fiedler RC. 1996. The reliability of the functional independence measure: a quantitative review. Arch Phys Med Rehabil 77: 1226-1232.","DOI":"10.1016\/S0003-9993(96)90184-7"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Desilets AR, Asal NJ, Dunican KC. 2012. Considerations for the use of proton-pump inhibitors in older adults. Consult Pharm 27: 114-120.","DOI":"10.4140\/TCP.n.2012.114"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Wakabayashi H, Matsushima M. 2016. Dysphagia assessed by the 10-item eating assessment tool is associated with nutritional status and activities of daily living in elderly individuals requiring long-term care. J Nutr Health Aging 20: 22-27.","DOI":"10.1007\/s12603-016-0671-8"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Goisser S, Schrader E, Singler K, Bertsch T, Gefeller O, Biber R, Bail HJ, Sieber CC, Volkert D. 2015. Malnutrition according to mini nutritional assessment is associated with severe functional impairment in geriatric patients before and up to 6 months after hip fracture. J Am Med Dir Assoc 16: 661-667.","DOI":"10.1016\/j.jamda.2015.03.002"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Koren-Hakim T, Weiss A, Hershkovitz A, Otzrateni I, Grosman B, Frishman S, Salai M, Beloosesky Y. 2012. The relationship between nutritional status of hip fracture operated elderly patients and their functioning, comorbidity and outcome. Clin Nutr 31: 917-921.","DOI":"10.1016\/j.clnu.2012.03.010"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Roqué M, Salvà A, Vellas B. 2013. Malnutrition in community-dwelling adults with dementia (NutriAlz Trial). J Nutr Health Aging 17: 295-299.","DOI":"10.1007\/s12603-012-0401-9"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Baldwin C, Spiro A, Ahern R, Emery PW. 2012. Oral nutritional interventions in malnourished patients with cancer: a systematic review and meta-analysis. J Natl Cancer Inst 104: 371-385.","DOI":"10.1093\/jnci\/djr556"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Love AL, Cornwell PL, Whitehouse SL. 2013. Oropharyngeal dysphagia in an elderly post-operative hip fracture population: a prospective cohort study. Age Ageing 42: 782-785.","DOI":"10.1093\/ageing\/aft037"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Alagiakrishnan K, Bhanji RA, Kurian M. 2013. Evaluation and management of oropharyngeal dysphagia in different types of dementia: a systematic review. Arch Gerontol Geriatr 56: 1-9.","DOI":"10.1016\/j.archger.2012.04.011"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) Cabrerizo S, Cuadras D, Gomez-Busto F, Artaza-Artabe I, Marín-Ciancas F, Malafarina V. 2015. Serum albumin and health in older people: Review and meta analysis. Maturitas 81: 17-27.","DOI":"10.1016\/j.maturitas.2015.02.009"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Bouillanne O, Hay P, Liabaud B, Duché C, Cynober L, Aussel C. 2011. Evidence that albumin is not a suitable marker of body composition-related nutritional status in elderly patients. Nutrition 27: 165-169.","DOI":"10.1016\/j.nut.2009.12.007"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33) Baek MH, Heo YR. 2015. Evaluation of the efficacy of nutritional screening tools to predict malnutrition in the elderly at a geriatric care hospital. Nutr Res Pract 9: 637-643.","DOI":"10.4162\/nrp.2015.9.6.637"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34) Kuzuya M, Kanda S, Koike T, Suzuki Y, Satake S, Iguchi A. 2005. Evaluation of mini-nutritional assessment for Japanese frail elderly. Nutrition 21: 498-503.","DOI":"10.1016\/j.nut.2004.08.023"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35) Wakabayashi H, Sashika H, Matsushima M. 2015. Head lifting strength is associated with dysphagia and malnutrition in frail older adults. Geriatr Gerontol Int 15: 410-416.","DOI":"10.1111\/ggi.12283"}],"container-title":["Journal of Nutritional Science and Vitaminology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jnsv\/62\/5\/62_330\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,16]],"date-time":"2019-09-16T07:49:17Z","timestamp":1568620157000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jnsv\/62\/5\/62_330\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.3177\/jnsv.62.330","relation":{},"ISSN":["0301-4800","1881-7742"],"issn-type":[{"value":"0301-4800","type":"print"},{"value":"1881-7742","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}