{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T03:33:15Z","timestamp":1762659195626,"version":"3.28.0"},"reference-count":17,"publisher":"Centers for Disease Control and Prevention (CDC)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Emerg. Infect. Dis."],"DOI":"10.3201\/eid1004.030247","type":"journal-article","created":{"date-parts":[[2012,5,15]],"date-time":"2012-05-15T13:36:27Z","timestamp":1337088987000},"page":"674-678","source":"Crossref","is-referenced-by-count":133,"title":["PorA Variable Regions of<i>Neisseria meningitidis<\/i>"],"prefix":"10.3201","volume":"10","author":[{"given":"Joanne E.","family":"Russell","sequence":"first","affiliation":[{"name":"University of Oxford, Oxford, United KingdomNational Institute for Biological Standards and Control, South Mimms Potters Bar, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith A.","family":"Jolley","sequence":"additional","affiliation":[{"name":"University of Oxford, Oxford, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian M.","family":"Feavers","sequence":"additional","affiliation":[{"name":"National Institute for Biological Standards and Control, South Mimms Potters Bar, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin C. J.","family":"Maiden","sequence":"additional","affiliation":[{"name":"University of Oxford, Oxford, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet","family":"Suker","sequence":"additional","affiliation":[{"name":"National Institute for Biological Standards and Control, South Mimms Potters Bar, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1822","published-online":{"date-parts":[[2004,4]]},"reference":[{"key":"key-10.3201\/eid1004.030247-201205150400-R1","doi-asserted-by":"crossref","unstructured":"Pollard AJ, Maiden MCJ. Meningococcal disease. Totowa (NJ): Humana Press; 2001.","DOI":"10.1385\/1592591493"},{"key":"key-10.3201\/eid1004.030247-201205150400-R2","doi-asserted-by":"crossref","unstructured":"Kuipers B, van den Dobbelsteen G, Wedege E, van Alphen L. Serological characterization. In: Pollard AJ, Maiden MC, editors. Meningococcal disease: methods and protocols. Totowa (NJ): Humana Press; 2001. p. 131\u201345.","DOI":"10.1385\/1-59259-149-3:131"},{"key":"key-10.3201\/eid1004.030247-201205150400-R3","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1093\/clinids\/7.4.504","article-title":"Serotype antigens of Neisseria meningitidis and a proposed scheme for designation of serotypes.","volume":"7","author":"Frasch","year":"1985","journal-title":"Rev Infect Dis"},{"key":"key-10.3201\/eid1004.030247-201205150400-R4","doi-asserted-by":"publisher","first-page":"2476","DOI":"10.1016\/S0264-410X(00)00047-5","article-title":"Effect of sequence variation in meningococcal PorA outer membrane protein on the effectiveness of a hexavalent PorA outer membrane vesicle vaccine.","volume":"18","author":"Martin","year":"2000","journal-title":"Vaccine"},{"key":"key-10.3201\/eid1004.030247-201205150400-R5","doi-asserted-by":"publisher","first-page":"1499","DOI":"10.1016\/S0140-6736(02)08416-7","article-title":"Development of vaccines against meningococcal disease.","volume":"359","author":"Jodar","year":"2002","journal-title":"Lancet"},{"key":"key-10.3201\/eid1004.030247-201205150400-R6","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1111\/j.1365-2958.1994.tb01014.x","article-title":"The porA gene in serogroup A meningococci: evolutionary stability and mechanism of genetic variation.","volume":"12","author":"Suker","year":"1994","journal-title":"Mol Microbiol"},{"key":"key-10.3201\/eid1004.030247-201205150400-R7","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1128\/CDLI.5.6.845-855.1998","article-title":"Proposed standardisation of Neisseria meningitidis PorA variable region typing nomenclature.","volume":"5","author":"Sacchi","year":"1998","journal-title":"Clin Diagn Lab Immunol"},{"key":"key-10.3201\/eid1004.030247-201205150400-R8","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1128\/CDLI.6.5.771-772.1999","article-title":"Neisseria meningitidis subtype nomenclature.","volume":"6","author":"Maiden","year":"1999","journal-title":"Clin Diagn Lab Immunol"},{"key":"key-10.3201\/eid1004.030247-201205150400-R9","doi-asserted-by":"publisher","first-page":"3140","DOI":"10.1073\/pnas.95.6.3140","article-title":"Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms.","volume":"95","author":"Maiden","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key-10.3201\/eid1004.030247-201205150400-R10","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1046\/j.1365-2958.1998.01101.x","article-title":"A gonococcal porA pseudogene: implications for understanding the evolution and pathogenicity of Neisseria gonorrhoeae.","volume":"30","author":"Feavers","year":"1998","journal-title":"Mol Microbiol"},{"key":"key-10.3201\/eid1004.030247-201205150400-R11","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1111\/j.1472-765X.1991.tb00600.x","article-title":"The linear PCR reaction: a simple and robust method for sequencing amplified rRNA genes.","volume":"13","author":"Embley","year":"1991","journal-title":"Lett Appl Microbiol"},{"key":"key-10.3201\/eid1004.030247-201205150400-R12","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1007\/BF02900361","article-title":"The Staden sequence analysis package.","volume":"5","author":"Staden","year":"1996","journal-title":"Mol Biotechnol"},{"key":"key-10.3201\/eid1004.030247-201205150400-R13","first-page":"3","article-title":"GCG: the Wisconsin Package of sequence analysis programs.","volume":"132","author":"Womble","year":"2000","journal-title":"Methods Mol Biol"},{"key":"key-10.3201\/eid1004.030247-201205150400-R14","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1093\/bioinformatics\/14.1.68","article-title":"SplitsTree: analyzing and visualizing evolutionary data.","volume":"14","author":"Huson","year":"1998","journal-title":"Bioinformatics"},{"key":"key-10.3201\/eid1004.030247-201205150400-R15","unstructured":"Russell J. Variation in the PorA protein and clonal diversity within the UKNeisseria meningitidispopulation over a twenty year period (1975\u20131995). [doctoral thesis]. Oxford: The Open University; 2001."},{"key":"key-10.3201\/eid1004.030247-201205150400-R16","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1093\/genetics\/98.3.641","article-title":"A model of evolutionary base substitutions and its application with special reference to rapid change of pseudogenes.","volume":"98","author":"Takahata","year":"1981","journal-title":"Genetics"},{"key":"key-10.3201\/eid1004.030247-201205150400-R17","doi-asserted-by":"publisher","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","article-title":"Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.","volume":"25","author":"Altschul","year":"1997","journal-title":"Nucleic Acids Res"}],"container-title":["Emerging Infectious Diseases"],"original-title":[],"link":[{"URL":"https:\/\/wwwnc.cdc.gov\/eid\/article\/10\/4\/03-0247_article","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T02:48:10Z","timestamp":1732589290000},"score":1,"resource":{"primary":{"URL":"http:\/\/wwwnc.cdc.gov\/eid\/article\/10\/4\/03-0247_article.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,4]]},"references-count":17,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2004,4]]}},"URL":"https:\/\/doi.org\/10.3201\/eid1004.030247","relation":{},"ISSN":["1080-6040","1080-6059"],"issn-type":[{"type":"print","value":"1080-6040"},{"type":"electronic","value":"1080-6059"}],"subject":[],"published":{"date-parts":[[2004,4]]}}}