{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T09:25:10Z","timestamp":1758705910271,"version":"3.30.0"},"reference-count":38,"publisher":"Centers for Disease Control and Prevention (CDC)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Emerg. Infect. Dis."],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.3201\/eid2302.161374","type":"journal-article","created":{"date-parts":[[2017,1,9]],"date-time":"2017-01-09T13:42:18Z","timestamp":1483969338000},"page":"241-251","source":"Crossref","is-referenced-by-count":16,"title":["Swine Influenza Virus (H1N2) Characterization and Transmission in Ferrets, Chile"],"prefix":"10.3201","volume":"23","author":[{"given":"Nicol\u00e1s","family":"Bravo-Vasquez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik A.","family":"Karlsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Jimenez-Bluhm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Meliopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryan","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shauna","family":"Marvin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerie","family":"Cortez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela","family":"Freiden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melinda A.","family":"Beck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Hamilton-West","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacey","family":"Schultz-Cherry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1822","reference":[{"key":"key-10.3201\/eid2302.161374-201701170900-R1","doi-asserted-by":"publisher","first-page":"6","DOI":"10.3201\/eid2001.121848","article-title":"A historical perspective of influenza A(H1N2) virus.","volume":"20","author":"Komadina","year":"2014","journal-title":"Emerg Infect Dis"},{"unstructured":"Centers for Disease Control and Prevention. Reported infections with variant influenza viruses in the United States since 2005. 2016 Sep 12 [cited 2016 Oct 10]. http:\/\/www.cdc.gov\/flu\/swineflu\/variant-cases-us.htm","key":"key-10.3201\/eid2302.161374-201701170900-R2"},{"unstructured":"Herriman R. Swine flu, H1N2v virus infections reported in Wisconsin, Minnesota. 2016 Jul 1 [cited 2016 Oct 10]. http:\/\/outbreaknewstoday.com\/swine-flu-h1n2v-virus-infections-reported-in-wisconsin-minnesota-22255\/","key":"key-10.3201\/eid2302.161374-201701170900-R3"},{"unstructured":"Centers for Disease Control and Prevention. Influenza A (H3N2) variant virus [cited 2016 Oct 6]. http:\/\/www.cdc.gov\/flu\/swineflu\/h3n2v-cases.htm","key":"key-10.3201\/eid2302.161374-201701170900-R4"},{"unstructured":"Centers for Disease Control and Prevention. H1N2 variant virus detected in Minnesota. 2012 Sep 7 [cited 2016 Oct 6]. http:\/\/www.cdc.gov\/flu\/spotlights\/h1n2v-cases-mn.htm","key":"key-10.3201\/eid2302.161374-201701170900-R5"},{"key":"key-10.3201\/eid2302.161374-201701170900-R6","doi-asserted-by":"publisher","first-page":"172","DOI":"10.3390\/vaccines3010172","article-title":"Emerging influenza strains in the last two decades: a threat of a new pandemic?","volume":"3","author":"Trombetta","year":"2015","journal-title":"Vaccines (Basel)"},{"key":"key-10.3201\/eid2302.161374-201701170900-R7","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1111\/zph.12139","article-title":"Variant influenza associated with live animal markets, Minnesota.","volume":"62","author":"Choi","year":"2015","journal-title":"Zoonoses Public Health"},{"key":"key-10.3201\/eid2302.161374-201701170900-R8","doi-asserted-by":"publisher","first-page":"2605","DOI":"10.1056\/NEJMoa0903810","article-title":"Emergence of a novel swine-origin influenza A (H1N1) virus in humans.","volume":"360","author":"Dawood","year":"2009","journal-title":"N Engl J Med"},{"key":"key-10.3201\/eid2302.161374-201701170900-R9","first-page":"7","article-title":"Novel human-like influenza A viruses circulate in swine in Mexico and Chile.","volume":"7","author":"Nelson","year":"2015","journal-title":"PLoS Curr"},{"key":"key-10.3201\/eid2302.161374-201701170900-R10","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.rvsc.2011.06.015","article-title":"Characterization of backyard poultry production systems and disease risk in the central zone of Chile.","volume":"93","author":"Hamilton-West","year":"2012","journal-title":"Res Vet Sci"},{"key":"key-10.3201\/eid2302.161374-201701170900-R11","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.prevetmed.2016.10.004","article-title":"Presence of influenza viruses in backyard poultry and swine in El Yali wetland, Chile.","volume":"134","author":"Bravo-Vasquez","year":"2016","journal-title":"Prev Vet Med"},{"key":"key-10.3201\/eid2302.161374-201701170900-R12","doi-asserted-by":"publisher","first-page":"e20","DOI":"10.1038\/emi.2013.20","article-title":"Prevalence and characterization of influenza viruses in diverse species in Los Llanos, Colombia.","volume":"2","author":"Karlsson","year":"2013","journal-title":"Emerg Microbes Infect"},{"doi-asserted-by":"crossref","unstructured":"Fulcher ML, Randell SH. Human nasal and tracheo-bronchial respiratory epithelial cell culture. In: Randell HS, Fulcher LM, editors. Epithelial cell culture protocols, 2nd ed. Totowa (NJ): Humana Press; 2013. p. 109\u201321.","key":"key-10.3201\/eid2302.161374-201701170900-R13","DOI":"10.1007\/978-1-62703-125-7_8"},{"key":"key-10.3201\/eid2302.161374-201701170900-R14","doi-asserted-by":"publisher","first-page":"9149","DOI":"10.1128\/JVI.00642-10","article-title":"Foot-and-mouth disease virus replicates only transiently in well-differentiated porcine nasal epithelial cells.","volume":"84","author":"Dash","year":"2010","journal-title":"J Virol"},{"key":"key-10.3201\/eid2302.161374-201701170900-R15","doi-asserted-by":"publisher","first-page":"piie00003-16","DOI":"10.1128\/mSphere.00003-16","article-title":"Novel highly pathogenic avian A(H5N2) and A(H5N8) influenza viruses of clade 2.3.4.4 from North America have limited capacity for replication and transmission in mammals","volume":"1","author":"Kaplan","year":"2016","journal-title":"mSphere"},{"key":"key-10.3201\/eid2302.161374-201701170900-R16","doi-asserted-by":"publisher","first-page":"11960","DOI":"10.1128\/JVI.01678-06","article-title":"Inhibition of influenza virus infection by a novel antiviral peptide that targets viral attachment to cells.","volume":"80","author":"Jones","year":"2006","journal-title":"J Virol"},{"key":"key-10.3201\/eid2302.161374-201701170900-R17","doi-asserted-by":"publisher","first-page":"e1001136","DOI":"10.1371\/journal.ppat.1001136","article-title":"Transforming growth factor-\u03b2: activation by neuraminidase and role in highly pathogenic H5N1 influenza pathogenesis.","volume":"6","author":"Carlson","year":"2010","journal-title":"PLoS Pathog"},{"key":"key-10.3201\/eid2302.161374-201701170900-R18","first-page":"95","article-title":"BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95\/98\/NT.","volume":"41","author":"Hall","year":"1999","journal-title":"Nucleic Acids Symp Ser"},{"key":"key-10.3201\/eid2302.161374-201701170900-R19","doi-asserted-by":"publisher","first-page":"1792","DOI":"10.1093\/nar\/gkh340","article-title":"MUSCLE: multiple sequence alignment with high accuracy and high throughput.","volume":"32","author":"Edgar","year":"2004","journal-title":"Nucleic Acids Res"},{"key":"key-10.3201\/eid2302.161374-201701170900-R20","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1128\/JVI.02005-07","article-title":"The influenza virus resource at the National Center for Biotechnology Information.","volume":"82","author":"Bao","year":"2008","journal-title":"J Virol"},{"key":"key-10.3201\/eid2302.161374-201701170900-R21","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1093\/bioinformatics\/btu033","article-title":"RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies.","volume":"30","author":"Stamatakis","year":"2014","journal-title":"Bioinformatics"},{"key":"key-10.3201\/eid2302.161374-201701170900-R22","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1038\/ijo.2011.208","article-title":"Obesity is associated with impaired immune response to influenza vaccination in humans.","volume":"36","author":"Sheridan","year":"2012","journal-title":"Int J Obes"},{"key":"key-10.3201\/eid2302.161374-201701170900-R23","doi-asserted-by":"publisher","first-page":"4791","DOI":"10.1038\/ncomms5791","article-title":"Respiratory transmission of an avian H3N8 influenza virus isolated from a harbour seal.","volume":"5","author":"Karlsson","year":"2014","journal-title":"Nat Commun"},{"key":"key-10.3201\/eid2302.161374-201701170900-R24","doi-asserted-by":"publisher","first-page":"12262","DOI":"10.1128\/JVI.05582-11","article-title":"Increased pathogenicity of a reassortant 2009 pandemic H1N1 influenza virus containing an H5N1 hemagglutinin.","volume":"85","author":"Cline","year":"2011","journal-title":"J Virol"},{"key":"key-10.3201\/eid2302.161374-201701170900-R25","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1093\/oxfordjournals.aje.a118408","article-title":"A simple methods of estimating fifty percent endpoints.","volume":"27","author":"Reed","year":"1938","journal-title":"Am J Epidemiol"},{"key":"key-10.3201\/eid2302.161374-201701170900-R26","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1093\/ilar.41.2.80","article-title":"A systematic approach for establishing humane endpoints.","volume":"41","author":"Morton","year":"2000","journal-title":"ILAR J"},{"key":"key-10.3201\/eid2302.161374-201701170900-R27","doi-asserted-by":"publisher","first-page":"8454","DOI":"10.1128\/JVI.00163-16","article-title":"Reversion of cold-adapted live attenuated influenza vaccine into a pathogenic virus.","volume":"90","author":"Zhou","year":"2016","journal-title":"J Virol"},{"key":"key-10.3201\/eid2302.161374-201701170900-R28","doi-asserted-by":"publisher","first-page":"e1002791","DOI":"10.1371\/journal.ppat.1002791","article-title":"Pathogenicity and transmissibility of North American triple reassortant swine influenza A viruses in ferrets.","volume":"8","author":"Barman","year":"2012","journal-title":"PLoS Pathog"},{"key":"key-10.3201\/eid2302.161374-201701170900-R29","doi-asserted-by":"publisher","first-page":"10110","DOI":"10.1128\/JVI.01080-14","article-title":"Introductions and evolution of human-origin seasonal influenza a viruses in multinational swine populations.","volume":"88","author":"Nelson","year":"2014","journal-title":"J Virol"},{"key":"key-10.3201\/eid2302.161374-201701170900-R30","doi-asserted-by":"publisher","first-page":"11825","DOI":"10.1128\/JVI.74.24.11825-11831.2000","article-title":"Sialic acid species as a determinant of the host range of influenza A viruses.","volume":"74","author":"Suzuki","year":"2000","journal-title":"J Virol"},{"key":"key-10.3201\/eid2302.161374-201701170900-R31","doi-asserted-by":"crossref","first-page":"7367","DOI":"10.1128\/JVI.72.9.7367-7373.1998","article-title":"Molecular basis for the generation in pigs of influenza A viruses with pandemic potential.","volume":"72","author":"Ito","year":"1998","journal-title":"J Virol"},{"key":"key-10.3201\/eid2302.161374-201701170900-R32","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.vetmic.2014.11.031","article-title":"Two different genotypes of H1N2 swine influenza virus isolated in northern China and their pathogenicity in animals.","volume":"175","author":"Yang","year":"2015","journal-title":"Vet Microbiol"},{"key":"key-10.3201\/eid2302.161374-201701170900-R33","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1016\/j.meegid.2015.06.005","article-title":"Evaluation of the zoonotic potential of a novel reassortant H1N2 swine influenza virus with gene constellation derived from multiple viral sources.","volume":"34","author":"Lee","year":"2015","journal-title":"Infect Genet Evol"},{"key":"key-10.3201\/eid2302.161374-201701170900-R34","doi-asserted-by":"publisher","first-page":"1603","DOI":"10.1099\/vir.0.000094","article-title":"New reassortant and enzootic European swine influenza viruses transmit efficiently through direct contact in the ferret model.","volume":"96","author":"Fobian","year":"2015","journal-title":"J Gen Virol"},{"key":"key-10.3201\/eid2302.161374-201701170900-R35","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.3201\/eid2108.141891","article-title":"Influenza A viruses of human origin in swine, Brazil.","volume":"21","author":"Nelson","year":"2015","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2302.161374-201701170900-R36","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1007\/s11262-016-1303-4","article-title":"Molecular characterization of a novel reassortant H1N2 influenza virus containing genes from the 2009 pandemic human H1N1 virus in swine from eastern China.","volume":"52","author":"Peng","year":"2016","journal-title":"Virus Genes"},{"key":"key-10.3201\/eid2302.161374-201701170900-R37","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/j.biologicals.2016.05.002","article-title":"Pathogenic characteristics of a novel triple-reasserted H1N2 swine influenza virus.","volume":"44","author":"Liu","year":"2016","journal-title":"Biologicals"},{"key":"key-10.3201\/eid2302.161374-201701170900-R38","doi-asserted-by":"publisher","first-page":"15900","DOI":"10.1073\/pnas.1205576109","article-title":"Virulence and transmissibility of H1N2 influenza virus in ferrets imply the continuing threat of triple-reassortant swine viruses.","volume":"109","author":"Pascua","year":"2012","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["Emerging Infectious Diseases"],"original-title":[],"link":[{"URL":"https:\/\/wwwnc.cdc.gov\/eid\/article\/23\/2\/16-1374_article","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T23:30:41Z","timestamp":1732923041000},"score":1,"resource":{"primary":{"URL":"http:\/\/wwwnc.cdc.gov\/eid\/article\/23\/2\/16-1374_article.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"URL":"https:\/\/doi.org\/10.3201\/eid2302.161374","relation":{},"ISSN":["1080-6040","1080-6059"],"issn-type":[{"type":"print","value":"1080-6040"},{"type":"electronic","value":"1080-6059"}],"subject":[],"published":{"date-parts":[[2017,2]]}}}