{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T04:27:00Z","timestamp":1793852820022,"version":"4.6.1"},"reference-count":37,"publisher":"Centers for Disease Control and Prevention (CDC)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Emerg. Infect. Dis."],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.3201\/eid2502.181222","type":"journal-article","created":{"date-parts":[[2019,1,6]],"date-time":"2019-01-06T16:40:20Z","timestamp":1546792820000},"page":"281-289","source":"Crossref","is-referenced-by-count":112,"title":["Epidemiologic and Ecologic Investigations of Monkeypox, Likouala Department, Republic of the Congo, 2017"],"prefix":"10.3201","volume":"25","author":[{"given":"Reena H.","family":"Doshi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah Anne J.","family":"Guagliardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey B.","family":"Doty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelie Dzabatou","family":"Babeaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Matheny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jillybeth","family":"Burgado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Townsend","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clint N.","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panayampalli Subbian","family":"Satheshkumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nestor","family":"Ndakala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Therese","family":"Kanjingankolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lambert","family":"Kitembo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Malekani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lem\u2019s","family":"Kalemba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Pukuta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobi","family":"N\u2019kaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabien","family":"Kangoula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Moses","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea M.","family":"McCollum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary G.","family":"Reynolds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Vivien","family":"Mombouli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinori","family":"Nakazawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett W.","family":"Petersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1822","reference":[{"key":"key-10.3201\/eid2502.181222-201901151210-R1","first-page":"165","article-title":"Human monkeypox, 1970-79.","volume":"58","author":"Breman","year":"1980","journal-title":"Bull World Health Organ"},{"key":"key-10.3201\/eid2502.181222-201901151210-R2","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1093\/infdis\/154.4.551","article-title":"Human monkeypox: a study of 2,510 contacts of 214 patients.","volume":"154","author":"Jezek","year":"1986","journal-title":"J Infect Dis"},{"key":"key-10.3201\/eid2502.181222-201901151210-R3","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1093\/infdis\/156.2.293","article-title":"Human monkeypox: clinical features of 282 patients.","volume":"156","author":"Jezek","year":"1987","journal-title":"J Infect Dis"},{"key":"key-10.3201\/eid2502.181222-201901151210-R4","doi-asserted-by":"publisher","first-page":"D54","DOI":"10.1016\/j.vaccine.2011.04.014","article-title":"Status of human monkeypox: clinical disease, epidemiology and research.","volume":"29","author":"Damon","year":"2011","journal-title":"Vaccine"},{"key":"key-10.3201\/eid2502.181222-201901151210-R5","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1038\/nm1261","article-title":"Smallpox vaccine-induced antibodies are necessary and sufficient for protection against monkeypox virus.","volume":"11","author":"Edghill-Smith","year":"2005","journal-title":"Nat Med"},{"key":"key-10.3201\/eid2502.181222-201901151210-R6","doi-asserted-by":"publisher","first-page":"16262","DOI":"10.1073\/pnas.1005769107","article-title":"Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo.","volume":"107","author":"Rimoin","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key-10.3201\/eid2502.181222-201901151210-R7","doi-asserted-by":"publisher","first-page":"306","DOI":"10.15585\/mmwr.mm6710a5","article-title":"Emergence of Monkeypox - West and Central Africa, 1970-2017.","volume":"67","author":"Durski","year":"2018","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"key-10.3201\/eid2502.181222-201901151210-R8","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.3201\/eid2406.180017","article-title":"Reemergence of human monkeypox in Nigeria, 2017.","volume":"24","author":"Yinka-Ogunleye","year":"2018","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2502.181222-201901151210-R9","doi-asserted-by":"publisher","first-page":"e28295","DOI":"10.1371\/journal.pone.0028295","article-title":"Monkeypox disease transmission in an experimental setting: prairie dog animal model.","volume":"6","author":"Hutson","year":"2011","journal-title":"PLoS One"},{"key":"key-10.3201\/eid2502.181222-201901151210-R10","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1086\/505880","article-title":"Clinical manifestations of human monkeypox influenced by route of infection.","volume":"194","author":"Reynolds","year":"2006","journal-title":"J Infect Dis"},{"key":"key-10.3201\/eid2502.181222-201901151210-R11","unstructured":"Jezek Z, Fenner F. Human monkeypox. Monographs in virology. Basel: Karger; 1988."},{"key":"key-10.3201\/eid2502.181222-201901151210-R12","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/S0140-6736(86)90748-8","article-title":"Isolation of monkeypox virus from wild squirrel infected in nature.","volume":"1","author":"Khodakevich","year":"1986","journal-title":"Lancet"},{"key":"key-10.3201\/eid2502.181222-201901151210-R13","first-page":"115","article-title":"The role of squirrels in sustaining monkeypox virus transmission.","volume":"39","author":"Khodakevich","year":"1987","journal-title":"Trop Geogr Med"},{"key":"key-10.3201\/eid2502.181222-201901151210-R14","first-page":"56","article-title":"Monkeypox virus in relation to the ecological features surrounding human settlements in Bumba zone, Zaire.","volume":"39","author":"Khodakevich","year":"1987","journal-title":"Trop Geogr Med"},{"key":"key-10.3201\/eid2502.181222-201901151210-R15","doi-asserted-by":"publisher","first-page":"E283","DOI":"10.3390\/v9100283","article-title":"Assessing monkeypox virus prevalence in small mammals at the human\u2013animal interface in the Democratic Republic of the Congo.","volume":"9","author":"Doty","year":"2017","journal-title":"Viruses"},{"key":"key-10.3201\/eid2502.181222-201901151210-R16","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.vetmic.2009.08.026","article-title":"Zoonotic poxviruses.","volume":"140","author":"Essbauer","year":"2010","journal-title":"Vet Microbiol"},{"key":"key-10.3201\/eid2502.181222-201901151210-R17","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.3201\/eid2006.131329","article-title":"Fatal monkeypox in wild-living sooty mangabey, C\u00f4te d\u2019Ivoire, 2012.","volume":"20","author":"Radoni\u0107","year":"2014","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2502.181222-201901151210-R18","doi-asserted-by":"publisher","first-page":"335","DOI":"10.7589\/0090-3558-48.2.335","article-title":"Ecology and geography of human monkeypox case occurrences across Africa.","volume":"48","author":"Ellis","year":"2012","journal-title":"J Wildl Dis"},{"key":"key-10.3201\/eid2502.181222-201901151210-R19","first-page":"459","article-title":"Clinico-epidemiological features of monkeypox patients with an animal or human source of infection.","volume":"66","author":"Jezek","year":"1988","journal-title":"Bull World Health Organ"},{"key":"key-10.3201\/eid2502.181222-201901151210-R20","doi-asserted-by":"publisher","first-page":"982","DOI":"10.4269\/ajtmh.12-0758","article-title":"Detection of human monkeypox in the Republic of the Congo following intensive community education.","volume":"88","author":"Reynolds","year":"2013","journal-title":"Am J Trop Med Hyg"},{"key":"key-10.3201\/eid2502.181222-201901151210-R21","doi-asserted-by":"publisher","first-page":"428","DOI":"10.4269\/ajtmh.2005.73.428","article-title":"Extended interhuman transmission of monkeypox in a hospital community in the Republic of the Congo, 2003.","volume":"73","author":"Learned","year":"2005","journal-title":"Am J Trop Med Hyg"},{"key":"key-10.3201\/eid2502.181222-201901151210-R22","unstructured":"Ministry of Economy, Territory Development and Integration, Centre National de la Statisque et des \u00c9tudes Economiques. Le RGPH-2007 en quelques chiffres. Brazzaville, Republic of Congo; 2010 [cited 2018 Apr 5]. http:\/\/www.cnsee.org\/pdf\/rgph2007pd.pdf"},{"key":"key-10.3201\/eid2502.181222-201901151210-R23","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.4269\/ajtmh.2007.77.1150","article-title":"Prevalence of antibodies against orthopoxviruses among residents of Likouala region, Republic of Congo: evidence for monkeypox virus exposure.","volume":"77","author":"Lederman","year":"2007","journal-title":"Am J Trop Med Hyg"},{"key":"key-10.3201\/eid2502.181222-201901151210-R24","doi-asserted-by":"publisher","first-page":"503","DOI":"10.4269\/ajtmh.2009.80.503","article-title":"Monkeypox or varicella? Lessons from a rash outbreak investigation in the Republic of the Congo.","volume":"80","author":"MacNeil","year":"2009","journal-title":"Am J Trop Med Hyg"},{"key":"key-10.3201\/eid2502.181222-201901151210-R25","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1128\/CDLI.12.7.867-872.2005","article-title":"characterization of acute-phase humoral immunity to monkeypox: use of immunoglobulin M enzyme-linked immunosorbent assay for detection of monkeypox infection during the 2003 North American outbreak.","volume":"12","author":"Karem","year":"2005","journal-title":"Clin Diagn Lab Immunol"},{"key":"key-10.3201\/eid2502.181222-201901151210-R26","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.3201\/eid2406.180248","article-title":"Strengthening of surveillance during monkeypox outbreak, Republic of the Congo, 2017.","volume":"24","author":"Doshi","year":"2018","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2502.181222-201901151210-R27","doi-asserted-by":"publisher","first-page":"5061","DOI":"10.5194\/bg-9-5061-2012","article-title":"Mapping Congo Basin vegetation types from 300 m and 1 km multi-sensor time series for carbon stocks and forest areas estimation.","volume":"9","author":"Verhegghen","year":"2012","journal-title":"Biogeosciences"},{"key":"key-10.3201\/eid2502.181222-201901151210-R28","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/j.jcv.2006.03.012","article-title":"Detection of monkeypox virus with real-time PCR assays.","volume":"36","author":"Li","year":"2006","journal-title":"J Clin Virol"},{"key":"key-10.3201\/eid2502.181222-201901151210-R29","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1111\/j.1095-8312.1993.tb00924.x","article-title":"The diversification of South American murid rodents: evidence from mitochondrial DNA sequence data for the akodontine tribe.","volume":"50","author":"Smith","year":"1993","journal-title":"Biol J Linn Soc Lond"},{"key":"key-10.3201\/eid2502.181222-201901151210-R30","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1644\/1545-1542(2000)081<0332:CSISHE>2.0.CO;2","article-title":"Cryptic species in Sigmodon hispidus: evidence from DNA sequences.","volume":"81","author":"Peppers","year":"2000","journal-title":"J Mammal"},{"key":"key-10.3201\/eid2502.181222-201901151210-R31","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1111\/j.1096-3642.2012.00823.x","article-title":"Taxonomy of the African giant pouched rats (Nesomyidae: Cricetomys): molecular and craniometric evidence support an unexpected high species diversity.","volume":"165","author":"Olayemi","year":"2012","journal-title":"Zool J Linn Soc"},{"key":"key-10.3201\/eid2502.181222-201901151210-R32","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1093\/bioinformatics\/17.8.754","article-title":"MRBAYES: Bayesian inference of phylogenetic trees.","volume":"17","author":"Huelsenbeck","year":"2001","journal-title":"Bioinformatics"},{"key":"key-10.3201\/eid2502.181222-201901151210-R33","doi-asserted-by":"publisher","first-page":"1572","DOI":"10.1093\/bioinformatics\/btg180","article-title":"MrBayes 3: Bayesian phylogenetic inference under mixed models.","volume":"19","author":"Ronquist","year":"2003","journal-title":"Bioinformatics"},{"key":"key-10.3201\/eid2502.181222-201901151210-R34","unstructured":"Musser GG. Superfamily Muroidea. In: Wilson DE, Reeder DM, editors. Mammal species of the world, 3rd edition. Baltimore: The Johns Hopkins University Press; 2005. p. 894\u20131531."},{"key":"key-10.3201\/eid2502.181222-201901151210-R35","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1093\/ije\/17.3.643","article-title":"The transmission potential of monkeypox virus in human populations.","volume":"17","author":"Fine","year":"1988","journal-title":"Int J Epidemiol"},{"key":"key-10.3201\/eid2502.181222-201901151210-R36","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1093\/oxfordjournals.aje.a114747","article-title":"Stochastic model for interhuman spread of monkeypox.","volume":"126","author":"Jezek","year":"1987","journal-title":"Am J Epidemiol"},{"key":"key-10.3201\/eid2502.181222-201901151210-R37","doi-asserted-by":"publisher","first-page":"e0004013","DOI":"10.1371\/journal.pntd.0004013","article-title":"Laboratory investigations of African pouched rats (Cricetomys gambianus) as a potential reservoir host species for monkeypox virus.","volume":"9","author":"Hutson","year":"2015","journal-title":"PLoS Negl Trop Dis"}],"container-title":["Emerging Infectious Diseases"],"original-title":[],"link":[{"URL":"https:\/\/wwwnc.cdc.gov\/eid\/article\/25\/2\/18-1222_article","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,30]],"date-time":"2024-11-30T17:27:23Z","timestamp":1732987643000},"score":1,"resource":{"primary":{"URL":"http:\/\/wwwnc.cdc.gov\/eid\/article\/25\/2\/18-1222_article.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2]]}},"URL":"https:\/\/doi.org\/10.3201\/eid2502.181222","relation":{},"ISSN":["1080-6040","1080-6059"],"issn-type":[{"value":"1080-6040","type":"print"},{"value":"1080-6059","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2]]}}}