{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T01:37:07Z","timestamp":1791423427421,"version":"4.3.3"},"reference-count":37,"publisher":"Centers for Disease Control and Prevention (CDC)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Emerg. Infect. Dis."],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.3201\/eid2509.190407","type":"journal-article","created":{"date-parts":[[2019,7,30]],"date-time":"2019-07-30T12:03:41Z","timestamp":1564488221000},"page":"1660-1667","source":"Crossref","is-referenced-by-count":34,"title":["Genetic Characterization and Enhanced Surveillance of Ceftriaxone-Resistant<i>Neisseria gonorrhoeae<\/i>Strain, Alberta, Canada, 2018"],"prefix":"10.3201","volume":"25","author":[{"given":"Byron M.","family":"Berenger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter","family":"Demczuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Gratrix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanti","family":"Pabbaraju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Smyczek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1822","reference":[{"key":"key-10.3201\/eid2509.190407-201908151151-R1","unstructured":"Centers for Disease Control and Prevention. Sexually transmitted disease surveillance 2017. Atlanta: The Centers; 2018."},{"key":"key-10.3201\/eid2509.190407-201908151151-R2","doi-asserted-by":"publisher","first-page":"37","DOI":"10.14745\/ccdr.v44i02a01","article-title":"Gonorrhea in Canada, 2010-2015.","volume":"44","author":"Choudhri","year":"2018","journal-title":"Can Commun Dis Rep"},{"key":"key-10.3201\/eid2509.190407-201908151151-R3","unstructured":"European Centre for Disease Prevention and Control. Control. ECDC Annual epidemiological report for 2016. Stockholm: The Centre; 2018."},{"key":"key-10.3201\/eid2509.190407-201908151151-R4","doi-asserted-by":"publisher","first-page":"148","DOI":"10.3201\/eid2404.171873","article-title":"Cooperative recognition of internationally disseminated ceftriaxone-resistant Neisseria gonorrhoeae strain.","volume":"24","author":"Lahra","year":"2018","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2509.190407-201908151151-R5","first-page":"1","article-title":"Recommendations for the laboratory-based detection of Chlamydia trachomatis and Neisseria gonorrhoeae\u20142014.","volume":"63","author":"Papp","year":"2014","journal-title":"MMWR Recomm Rep"},{"key":"key-10.3201\/eid2509.190407-201908151151-R6","unstructured":"Public Health Agency of Canada. Canadian guidelines on sexually transmitted infections. 2018 [cited 2019 Jul 3]. https:\/\/www.canada.ca\/en\/public-health\/services\/infectious-diseases\/sexual-health-sexually-transmitted-infections\/canadian-guidelines.html"},{"key":"key-10.3201\/eid2509.190407-201908151151-R7","doi-asserted-by":"publisher","first-page":"45","DOI":"10.14745\/ccdr.v45i23a01","article-title":"Multidrug-resistant and extensively drug-resistant Neisseria gonorrhoeae in Canada, 2012-2016.","volume":"45","author":"Martin","year":"2019","journal-title":"Can Commun Dis Rep"},{"key":"key-10.3201\/eid2509.190407-201908151151-R8","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1097\/OLQ.0000000000000707","article-title":"A comparison of real-time polymerase chain reaction assays for the detection of antimicrobial resistance markers and sequence typing from clinical nucleic acid amplification test samples and matched Neisseria gonorrhoeae culture.","volume":"45","author":"Peterson","year":"2018","journal-title":"Sex Transm Dis"},{"key":"key-10.3201\/eid2509.190407-201908151151-R9","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1136\/sti.2008.029694","article-title":"Prediction of antibiotic resistance using Neisseria gonorrhoeae multi-antigen sequence typing.","volume":"84","author":"Palmer","year":"2008","journal-title":"Sex Transm Infect"},{"key":"key-10.3201\/eid2509.190407-201908151151-R10","doi-asserted-by":"publisher","first-page":"1573","DOI":"10.3201\/eid2408.180295","article-title":"Direct detection of penA gene associated with ceftriaxone-resistant Neisseria gonorrhoeae FC428 strain by using PCR.","volume":"24","author":"Whiley","year":"2018","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2509.190407-201908151151-R11","doi-asserted-by":"publisher","first-page":"381","DOI":"10.3201\/eid2402.171756","article-title":"Ceftriaxone-Resistant Neisseria gonorrhoeae, Canada, 2017.","volume":"24","author":"Lefebvre","year":"2018","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2509.190407-201908151151-R12","article-title":"A case of an emerging international strain of multi-drug resistant Neisseria gonorrhoeae infection in a male with urethral discharge.","author":"Smyczek","year":"2019","journal-title":"Can Fam Physician"},{"key":"key-10.3201\/eid2509.190407-201908151151-R13","unstructured":"Alberta Health Services. AHS map and zone overview. 2017 [cited 2019 Feb 19]. https:\/\/www.albertahealthservices.ca\/assets\/about\/publications\/ahs-ar-2017\/zones.html"},{"key":"key-10.3201\/eid2509.190407-201908151151-R14","unstructured":"Clinical Laboratory Standards Institute (CLSI). Performance standards for antimicrobial susceptibility testing; twenty-eighth informational supplement. Wayne (PA): The Institute; 2018."},{"key":"key-10.3201\/eid2509.190407-201908151151-R15","unstructured":"Clinical Laboratory Standards Institute (CLSI). Performance standards for antimicrobial susceptibility testing; twenty-ninth informational supplement. Wayne (PA): The Institute; 2019."},{"key":"key-10.3201\/eid2509.190407-201908151151-R16","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1097\/00007435-199607000-00004","article-title":"A clinical isolate of Neisseria gonorrhoeae with in vitro resistance to erythromycin and decreased susceptibility to azithromycin.","volume":"23","author":"Ehret","year":"1996","journal-title":"Sex Transm Dis"},{"key":"key-10.3201\/eid2509.190407-201908151151-R17","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1093\/jac\/dkp098","article-title":"Phenotypic and genetic characterization of the 2008 WHO Neisseria gonorrhoeae reference strain panel intended for global quality assurance and quality control of gonococcal antimicrobial resistance surveillance for public health purposes.","volume":"63","author":"Unemo","year":"2009","journal-title":"J Antimicrob Chemother"},{"key":"key-10.3201\/eid2509.190407-201908151151-R18","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1097\/OLQ.0b013e3181bf575c","article-title":"Neisseria gonorrhoeae antimicrobial susceptibility in Lilongwe, Malawi, 2007.","volume":"37","author":"Brown","year":"2010","journal-title":"Sex Transm Dis"},{"key":"key-10.3201\/eid2509.190407-201908151151-R19","doi-asserted-by":"crossref","first-page":"2985","DOI":"10.1128\/JCM.35.11.2985-2988.1997","article-title":"Development of an antimicrobial susceptibility surveillance system for Neisseria gonorrhoeae in Malawi: comparison of methods.","volume":"35","author":"Daly","year":"1997","journal-title":"J Clin Microbiol"},{"key":"key-10.3201\/eid2509.190407-201908151151-R20","doi-asserted-by":"publisher","first-page":"2957","DOI":"10.1093\/bioinformatics\/btr507","article-title":"FLASH: fast length adjustment of short reads to improve genome assemblies.","volume":"27","author":"Mago\u010d","year":"2011","journal-title":"Bioinformatics"},{"key":"key-10.3201\/eid2509.190407-201908151151-R21","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1089\/cmb.2012.0021","article-title":"SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing.","volume":"19","author":"Bankevich","year":"2012","journal-title":"J Comput Biol"},{"key":"key-10.3201\/eid2509.190407-201908151151-R22","doi-asserted-by":"publisher","first-page":"e000116","DOI":"10.1099\/mgen.0.000116","article-title":"SNVPhyl: a single nucleotide variant phylogenomics pipeline for microbial genomic epidemiology.","volume":"3","author":"Petkau","year":"2017","journal-title":"Microb Genom"},{"key":"key-10.3201\/eid2509.190407-201908151151-R23","doi-asserted-by":"publisher","first-page":"3096","DOI":"10.1093\/jac\/dkw288","article-title":"The novel 2016 WHO Neisseria gonorrhoeae reference strains for global quality assurance of laboratory investigations: phenotypic, genetic and reference genome characterization.","volume":"71","author":"Unemo","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"key-10.3201\/eid2509.190407-201908151151-R24","doi-asserted-by":"publisher","first-page":"1497","DOI":"10.1086\/383047","article-title":"Rapid sequence-based identification of gonococcal transmission clusters in a large metropolitan area.","volume":"189","author":"Martin","year":"2004","journal-title":"J Infect Dis"},{"key":"key-10.3201\/eid2509.190407-201908151151-R25","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1186\/1471-2105-11-595","article-title":"BIGSdb: Scalable analysis of bacterial genome variation at the population level.","volume":"11","author":"Jolley","year":"2010","journal-title":"BMC Bioinformatics"},{"key":"key-10.3201\/eid2509.190407-201908151151-R26","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1128\/JCM.00100-17","article-title":"Neisseria gonorrhoeae sequence typing for antimicrobial resistance, a novel antimicrobial resistance multilocus typing scheme for tracking global dissemination of N. gonorrhoeae strains.","volume":"55","author":"Demczuk","year":"2017","journal-title":"J Clin Microbiol"},{"key":"key-10.3201\/eid2509.190407-201908151151-R27","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1128\/AAC.00788-10","article-title":"Molecular analysis of antimicrobial resistance mechanisms in Neisseria gonorrhoeae isolates from Ontario, Canada.","volume":"55","author":"Allen","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"key":"key-10.3201\/eid2509.190407-201908151151-R28","first-page":"3244","article-title":"Direct real-time PCR-based detection of Neisseria gonorrhoeae 23S rRNA mutations associated with azithromycin resistance.","volume":"70","author":"Trembizki","year":"2015","journal-title":"J Antimicrob Chemother"},{"key":"key-10.3201\/eid2509.190407-201908151151-R29","doi-asserted-by":"crossref","unstructured":"Peterson SW, Martin I, Demczuk W, Bharat A, Hoang L, Wylie J, Molecular assay for detection of genetic markers associated with decreased susceptibility to cephalosporins inNeisseria gonorrhoeae. Ledeboer NA, editor. J Clin Microbiol. 2015;53:2042\u20138.","DOI":"10.1128\/JCM.00493-15"},{"key":"key-10.3201\/eid2509.190407-201908151151-R30","unstructured":"Canada S. Census profile, 2016 census. Ottawa, ON, Canada. November 29, 2017 [cited 2019 Jul 12]. https:\/\/www12.statcan.gc.ca\/census-recensement\/2016\/dp-pd\/prof\/index.cfm"},{"key":"key-10.3201\/eid2509.190407-201908151151-R31","doi-asserted-by":"publisher","first-page":"63","DOI":"10.3390\/antibiotics7030063","article-title":"Surveillance for antimicrobial resistance in gonorrhea: the Alberta model, 2012\u20132016.","volume":"7","author":"Gratrix","year":"2018","journal-title":"Antibiotics (Basel)"},{"key":"key-10.3201\/eid2509.190407-201908151151-R32","doi-asserted-by":"publisher","first-page":"3603","DOI":"10.1128\/AAC.00326-12","article-title":"In vitro activity of ertapenem versus ceftriaxone against Neisseria gonorrhoeae isolates with highly diverse ceftriaxone MIC values and effects of ceftriaxone resistance determinants: ertapenem for treatment of gonorrhea?","volume":"56","author":"Unemo","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"key-10.3201\/eid2509.190407-201908151151-R33","doi-asserted-by":"publisher","first-page":"4339","DOI":"10.1128\/AAC.00504-16","article-title":"New ceftriaxone- and multidrug-resistant Neisseria gonorrhoeae strain with a novel mosaic penA gene isolated in Japan.","volume":"60","author":"Nakayama","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"key":"key-10.3201\/eid2509.190407-201908151151-R34","doi-asserted-by":"publisher","first-page":"e1002344","DOI":"10.2807\/1560-7917.ES.2018.23.21.1800264","article-title":"Multidrug-resistant Neisseria gonorrhoeae failing treatment with ceftriaxone and doxycycline in France, November 2017.","volume":"23","author":"Poncin","year":"2018","journal-title":"Euro Surveill"},{"key":"key-10.3201\/eid2509.190407-201908151151-R35","doi-asserted-by":"publisher","first-page":"804","DOI":"10.3201\/eid2404.171817","article-title":"Cephalosporin-resistant Neisseria gonorrhoeae clone, China.","volume":"24","author":"Chen","year":"2018","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2509.190407-201908151151-R36","unstructured":"World Health Organization. Global action plan to control the spread and impact of antimicrobial resistance inNeisseria gonorrhoeae. 2012 [cited 2019 Jul 3]. www.who.int\/reproductivehealth\/publications\/rtis\/9789241503501"},{"key":"key-10.3201\/eid2509.190407-201908151151-R37","doi-asserted-by":"publisher","first-page":"364","DOI":"10.2807\/1560-7917.ES.2018.23.27.1800323","article-title":"Gonorrhoea treatment failure caused by a Neisseria gonorrhoeae strain with combined ceftriaxone and high-level azithromycin resistance, England, February 2018.","volume":"23","author":"Eyre","year":"2018","journal-title":"Euro Surveill"}],"container-title":["Emerging Infectious Diseases"],"original-title":[],"link":[{"URL":"https:\/\/wwwnc.cdc.gov\/eid\/article\/25\/9\/19-0407_article","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,30]],"date-time":"2024-11-30T17:30:08Z","timestamp":1732987808000},"score":1,"resource":{"primary":{"URL":"http:\/\/wwwnc.cdc.gov\/eid\/article\/25\/9\/19-0407_article.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":37,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9]]}},"URL":"https:\/\/doi.org\/10.3201\/eid2509.190407","relation":{},"ISSN":["1080-6040","1080-6059"],"issn-type":[{"value":"1080-6040","type":"print"},{"value":"1080-6059","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9]]}}}