{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T09:10:35Z","timestamp":1790759435841,"version":"4.1.0"},"reference-count":50,"publisher":"Centers for Disease Control and Prevention (CDC)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Emerg. Infect. Dis."],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.3201\/eid2812.220552","type":"journal-article","created":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T11:01:16Z","timestamp":1670583676000},"page":"2416-2424","source":"Crossref","is-referenced-by-count":38,"title":["Continued Circulation of Tick-Borne Encephalitis Virus Variants and Detection of Novel Transmission Foci, the Netherlands"],"prefix":"10.3201","volume":"28","author":[{"given":"Helen J.","family":"Esser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie M.","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankje","family":"de Vries","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hein","family":"Sprong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinant J.","family":"Dekker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily L.","family":"Pascoe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian W.","family":"Bakker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Suin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eelco","family":"Franz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byron E.E.","family":"Martina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantianus J.M.","family":"Koenraadt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1822","reference":[{"key":"key-10.3201\/eid2812.220552-202211191153-R1","doi-asserted-by":"publisher","first-page":"430","DOI":"10.12998\/wjcc.v3.i5.430","article-title":"Tick-borne encephalitis: A review of epidemiology, clinical characteristics, and management.","volume":"3","author":"Bogovic","year":"2015","journal-title":"World J Clin Cases"},{"key":"key-10.3201\/eid2812.220552-202211191153-R2","doi-asserted-by":"publisher","first-page":"1800201","DOI":"10.2807\/1560-7917.ES.2018.23.45.1800201","article-title":"Tick-borne encephalitis in Europe, 2012 to 2016.","volume":"23","author":"Beaut\u00e9","year":"2018","journal-title":"Euro Surveill"},{"key":"key-10.3201\/eid2812.220552-202211191153-R3","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.ttbdis.2010.10.007","article-title":"Tick-borne encephalitis 2010: epidemiology, risk areas, and virus strains in Europe and Asia-an overview.","volume":"2","author":"S\u00fcss","year":"2011","journal-title":"Ticks Tick Borne Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R4","doi-asserted-by":"publisher","first-page":"e4336","DOI":"10.1371\/journal.pone.0004336","article-title":"Forest structure and roe deer abundance predict tick-borne encephalitis risk in Italy.","volume":"4","author":"Rizzoli","year":"2009","journal-title":"PLoS One"},{"key":"key-10.3201\/eid2812.220552-202211191153-R5","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1002\/rmv.566","article-title":"Socio-economic factors in the differential upsurge of tick-borne encephalitis in Central and Eastern Europe.","volume":"18","author":"\u0160umilo","year":"2008","journal-title":"Rev Med Virol"},{"key":"key-10.3201\/eid2812.220552-202211191153-R6","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1186\/s13071-018-3057-4","article-title":"The importance of wildlife in the ecology and epidemiology of the TBE virus in Sweden: incidence of human TBE correlates with abundance of deer and hares.","volume":"11","author":"Jaenson","year":"2018","journal-title":"Parasit Vectors"},{"key":"key-10.3201\/eid2812.220552-202211191153-R7","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1017\/S0031182098003643","article-title":"Incidence from coincidence: patterns of tick infestations on rodents facilitate transmission of tick-borne encephalitis virus.","volume":"118","author":"Randolph","year":"1999","journal-title":"Parasitology"},{"key":"key-10.3201\/eid2812.220552-202211191153-R8","doi-asserted-by":"publisher","first-page":"90","DOI":"10.3201\/eid2601.191085","article-title":"Tick-borne encephalitis virus, United Kingdom.","volume":"26","author":"Holding","year":"2020","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R9","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.ttbdis.2018.10.008","article-title":"Emergence of tick-borne encephalitis (TBE) in the Netherlands.","volume":"10","author":"Dekker","year":"2019","journal-title":"Ticks Tick Borne Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R10","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1098\/rstb.2001.0893","article-title":"The shifting landscape of tick-borne zoonoses: tick-borne encephalitis and Lyme borreliosis in Europe.","volume":"356","author":"Randolph","year":"2001","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"key-10.3201\/eid2812.220552-202211191153-R11","doi-asserted-by":"publisher","first-page":"20003","DOI":"10.2807\/ese.16.44.20003-en","article-title":"Case report: tick-borne encephalitis in two Dutch travellers returning from Austria, Netherlands, July and August 2011.","volume":"16","author":"Reusken","year":"2011","journal-title":"Euro Surveill"},{"key":"key-10.3201\/eid2812.220552-202211191153-R12","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1089\/vbz.2005.5.58","article-title":"Attempt to detect evidence for tick-borne encephalitis virus in ticks and mammalian wildlife in The Netherlands.","volume":"5","author":"van der Poel","year":"2005","journal-title":"Vector Borne Zoonotic Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R13","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.3201\/eid2306.161247","article-title":"Tick-borne encephalitis virus in ticks and roe deer, the Netherlands.","volume":"23","author":"Jahfari","year":"2017","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R14","doi-asserted-by":"publisher","first-page":"342","DOI":"10.3201\/eid2502.181386","article-title":"Tick-borne encephalitis virus antibodies in roe deer, the Netherlands.","volume":"25","author":"Rijks","year":"2019","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R15","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1186\/s13071-020-04339-0","article-title":"Spatial risk analysis for the introduction and circulation of six arboviruses in the Netherlands.","volume":"13","author":"Esser","year":"2020","journal-title":"Parasit Vectors"},{"key":"key-10.3201\/eid2812.220552-202211191153-R16","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1007\/s10528-011-9487-8","article-title":"Molecular identification of small mammal species using novel cytochrome B gene-derived degenerated primers.","volume":"50","author":"Schlegel","year":"2012","journal-title":"Biochem Genet"},{"key":"key-10.3201\/eid2812.220552-202211191153-R17","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/S1386-6532(02)00168-3","article-title":"Development of a quantitative real-time RT-PCR assay with internal control for the laboratory detection of tick borne encephalitis virus (TBEV) RNA.","volume":"27","author":"Schwaiger","year":"2003","journal-title":"J Clin Virol"},{"key":"key-10.3201\/eid2812.220552-202211191153-R18","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.ttbdis.2009.11.002","article-title":"Isolation and molecular characterization of a tick-borne encephalitis virus strain from a new tick-borne encephalitis focus with severe cases in Bavaria, Germany.","volume":"1","author":"Kup\u010da","year":"2010","journal-title":"Ticks Tick Borne Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R19","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1093\/molbev\/msy096","article-title":"MEGA X: molecular evolutionary genetics analysis across computing platforms.","volume":"35","author":"Kumar","year":"2018","journal-title":"Mol Biol Evol"},{"key":"key-10.3201\/eid2812.220552-202211191153-R20","doi-asserted-by":"publisher","first-page":"1792","DOI":"10.1093\/nar\/gkh340","article-title":"MUSCLE: multiple sequence alignment with high accuracy and high throughput.","volume":"32","author":"Edgar","year":"2004","journal-title":"Nucleic Acids Res"},{"key":"key-10.3201\/eid2812.220552-202211191153-R21","doi-asserted-by":"crossref","unstructured":"Nei M, Kumar S. Molecular evolution and phylogenetics. New York: Oxford University Press; 2000.","DOI":"10.1093\/oso\/9780195135848.001.0001"},{"key":"key-10.3201\/eid2812.220552-202211191153-R22","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1038\/nmeth.2109","article-title":"jModelTest 2: more models, new heuristics and parallel computing.","volume":"9","author":"Darriba","year":"2012","journal-title":"Nat Methods"},{"key":"key-10.3201\/eid2812.220552-202211191153-R23","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1089\/vbz.2014.1576","article-title":"Autochthonous tick-borne encephalitis virus-seropositive cattle in Belgium: a risk-based targeted serological survey.","volume":"14","author":"Roelandt","year":"2014","journal-title":"Vector Borne Zoonotic Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R24","doi-asserted-by":"publisher","first-page":"30318","DOI":"10.2807\/1560-7917.ES.2016.21.33.30318","article-title":"First human case of tick-borne encephalitis virus infection acquired in the Netherlands, July 2016.","volume":"21","author":"de Graaf","year":"2016","journal-title":"Euro Surveill"},{"key":"key-10.3201\/eid2812.220552-202211191153-R25","doi-asserted-by":"publisher","first-page":"101557","DOI":"10.1016\/j.ttbdis.2020.101557","article-title":"High-throughput sequencing of two European strains of tick-borne encephalitis virus (TBEV), Hochosterwitz and 1993\/783.","volume":"12","author":"Paulsen","year":"2021","journal-title":"Ticks Tick Borne Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R26","doi-asserted-by":"publisher","first-page":"e0204790","DOI":"10.1371\/journal.pone.0204790","article-title":"Phylogenetics of tick-borne encephalitis virus in endemic foci in the upper Rhine region in France and Germany.","volume":"13","author":"Bestehorn","year":"2018","journal-title":"PLoS One"},{"key":"key-10.3201\/eid2812.220552-202211191153-R27","doi-asserted-by":"publisher","first-page":"e48420","DOI":"10.1371\/journal.pone.0048420","article-title":"Phylogeographic characterization of tick-borne encephalitis virus from patients, rodents and ticks in Slovenia.","volume":"7","author":"Fajs","year":"2012","journal-title":"PLoS One"},{"key":"key-10.3201\/eid2812.220552-202211191153-R28","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1186\/s13071-020-04146-7","article-title":"Tick-borne encephalitis virus (TBEV) prevalence in field-collected ticks (Ixodes ricinus) and phylogenetic, structural and virulence analysis in a TBE high-risk endemic area in southwestern Germany.","volume":"13","author":"Ott","year":"2020","journal-title":"Parasit Vectors"},{"key":"key-10.3201\/eid2812.220552-202211191153-R29","doi-asserted-by":"publisher","first-page":"2129","DOI":"10.1099\/vir.0.054478-0","article-title":"Molecular phylogeography of tick-borne encephalitis virus in central Europe.","volume":"94","author":"Weidmann","year":"2013","journal-title":"J Gen Virol"},{"key":"key-10.3201\/eid2812.220552-202211191153-R30","doi-asserted-by":"publisher","first-page":"8663","DOI":"10.1128\/JVI.01013-12","article-title":"Revisiting the clinal concept of evolution and dispersal for the tick-borne flaviviruses by using phylogenetic and biogeographic analyses.","volume":"86","author":"Heinze","year":"2012","journal-title":"J Virol"},{"key":"key-10.3201\/eid2812.220552-202211191153-R31","doi-asserted-by":"publisher","first-page":"1900658","DOI":"10.2807\/1560-7917.ES.2019.24.47.1900658","article-title":"Detection of new endemic focus of tick-borne encephalitis virus (TBEV), Hampshire\/Dorset border, England, September 2019.","volume":"24","author":"Holding","year":"2019","journal-title":"Euro Surveill"},{"key":"key-10.3201\/eid2812.220552-202211191153-R32","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.3201\/eid1308.061416","article-title":"Migrating birds and tickborne encephalitis virus.","volume":"13","author":"Waldenstr\u00f6m","year":"2007","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R33","doi-asserted-by":"publisher","first-page":"e81214","DOI":"10.1371\/journal.pone.0081214","article-title":"The three subtypes of tick-borne encephalitis virus induce encephalitis in a natural host, the bank vole (Myodes glareolus).","volume":"8","author":"Tonteri","year":"2013","journal-title":"PLoS One"},{"key":"key-10.3201\/eid2812.220552-202211191153-R34","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1111\/j.1469-0691.2009.02764.x","article-title":"Tick-borne encephalitis (TBE) virus prevalence and virus genome characterization in field-collected ticks (Ixodes ricinus) from risk, non-risk and former risk areas of TBE, and in ticks removed from humans in Germany.","volume":"16","author":"Klaus","year":"2010","journal-title":"Clin Microbiol Infect"},{"key":"key-10.3201\/eid2812.220552-202211191153-R35","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1016\/j.ttbdis.2019.05.005","article-title":"Field samplings of Ixodes ricinus ticks from a tick-borne encephalitis virus micro-focus in Northern Zealand, Denmark.","volume":"10","author":"Petersen","year":"2019","journal-title":"Ticks Tick Borne Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R36","doi-asserted-by":"publisher","first-page":"930","DOI":"10.3390\/pathogens9110930","article-title":"Disappearance of TBEV circulation among rodents in a natural focus in Alsace, eastern France.","volume":"9","author":"Bournez","year":"2020","journal-title":"Pathogens"},{"key":"key-10.3201\/eid2812.220552-202211191153-R37","doi-asserted-by":"publisher","first-page":"308371","DOI":"10.1155\/2014\/308371","article-title":"Tick-borne encephalitis virus habitats in North East Germany: reemergence of TBEV in ticks after 15 years of inactivity.","volume":"2014","author":"Frimmel","year":"2014","journal-title":"BioMed Res Int"},{"key":"key-10.3201\/eid2812.220552-202211191153-R38","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.ttbdis.2011.09.011","article-title":"Goats and sheep as sentinels for tick-borne encephalitis (TBE) virus\u2014epidemiological studies in areas endemic and non-endemic for TBE virus in Germany.","volume":"3","author":"Klaus","year":"2012","journal-title":"Ticks Tick Borne Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R39","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1016\/j.ttbdis.2015.05.001","article-title":"Review: Sentinels of tick-borne encephalitis risk.","volume":"6","author":"Imhoff","year":"2015","journal-title":"Ticks Tick Borne Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R40","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1017\/S0950268800058477","article-title":"Roe deer as sentinels for endemicity of tick-borne encephalitis virus.","volume":"115","author":"Gerth","year":"1995","journal-title":"Epidemiol Infect"},{"key":"key-10.3201\/eid2812.220552-202211191153-R41","doi-asserted-by":"publisher","first-page":"1817","DOI":"10.3390\/microorganisms8111817","article-title":"The red fox (Vulpes vulpes) as sentinel for tick-borne encephalitis virus in endemic and non-endemic areas.","volume":"8","author":"Haut","year":"2020","journal-title":"Microorganisms"},{"key":"key-10.3201\/eid2812.220552-202211191153-R42","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1080\/22221751.2020.1730246","article-title":"Tick-borne encephalitis foci in northeast Italy revealed by combined virus detection in ticks, serosurvey on goats and human cases.","volume":"9","author":"Alfano","year":"2020","journal-title":"Emerg Microbes Infect"},{"key":"key-10.3201\/eid2812.220552-202211191153-R43","doi-asserted-by":"publisher","first-page":"101762","DOI":"10.1016\/j.ttbdis.2021.101762","article-title":"Exposure to tick-borne encephalitis virus among nature management workers in the Netherlands.","volume":"12","author":"Hofhuis","year":"2021","journal-title":"Ticks Tick Borne Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R44","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1111\/1365-2656.12105","article-title":"Seasonality, weather and climate affect home range size in roe deer across a wide latitudinal gradient within Europe.","volume":"82","author":"Morellet","year":"2013","journal-title":"J Anim Ecol"},{"key":"key-10.3201\/eid2812.220552-202211191153-R45","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1007\/BF01716097","article-title":"Diagnosis of tick-borne encephalitis: evaluation of sera with borderline titers with the TBE-ELISA.","volume":"24","author":"Dobler","year":"1996","journal-title":"Infection"},{"key":"key-10.3201\/eid2812.220552-202211191153-R46","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1089\/vbz.2010.0236","article-title":"Rodents as sentinels for the prevalence of tick-borne encephalitis virus.","volume":"11","author":"Achazi","year":"2011","journal-title":"Vector Borne Zoonotic Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R47","doi-asserted-by":"publisher","first-page":"72","DOI":"10.3201\/eid1701.100051","article-title":"Tick-borne encephalitis virus in wild rodents in winter, Finland, 2008-2009.","volume":"17","author":"Tonteri","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2812.220552-202211191153-R48","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1007\/BF00378782","article-title":"Changes in home range size during growth and maturation of the wood mouse (Apodemus sylvaticus) and the bank vole (Clethrionomys glareolus).","volume":"68","author":"Korn","year":"1986","journal-title":"Oecologia"},{"key":"key-10.3201\/eid2812.220552-202211191153-R49","first-page":"81","article-title":"Spatial organization and home range of Apodemus flavicollis and A. agrarius on Mt. Avala, Serbia.","volume":"52","author":"Vuki\u0107evi\u0107-Radi\u0107","year":"2006","journal-title":"Acta Zool Acad Sci Hung"},{"key":"key-10.3201\/eid2812.220552-202211191153-R50","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1111\/jvec.12241","article-title":"Tick infestation of small mammals in an English woodland.","volume":"42","author":"Cull","year":"2017","journal-title":"J Vector Ecol"}],"container-title":["Emerging Infectious Diseases"],"original-title":[],"link":[{"URL":"https:\/\/wwwnc.cdc.gov\/eid\/article\/28\/12\/22-0552_article","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,30]],"date-time":"2024-11-30T12:54:10Z","timestamp":1732971250000},"score":1,"resource":{"primary":{"URL":"https:\/\/wwwnc.cdc.gov\/eid\/article\/28\/12\/22-0552_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":50,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"URL":"https:\/\/doi.org\/10.3201\/eid2812.220552","relation":{},"ISSN":["1080-6040","1080-6059"],"issn-type":[{"value":"1080-6040","type":"print"},{"value":"1080-6059","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12]]}}}