{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T05:46:23Z","timestamp":1785390383090,"version":"3.55.0"},"reference-count":43,"publisher":"Centers for Disease Control and Prevention (CDC)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Emerg. Infect. Dis."],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.3201\/eid2905.221226","type":"journal-article","created":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T18:48:03Z","timestamp":1681325283000},"source":"Crossref","is-referenced-by-count":16,"title":["Phylogenetic Analysis of Transmission Dynamics of Dengue in Large and Small Population Centers, Northern Ecuador"],"prefix":"10.3201","volume":"29","author":[{"given":"Sully","family":"M\u00e1rquez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwenyth","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernardo","family":"Guti\u00e9rrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josefina","family":"Coloma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph N.S.","family":"Eisenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Trueba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1822","reference":[{"key":"key-10.3201\/eid2905.221226-202304111246-R1","unstructured":"World Health Organization. Dengue and severe dengue [cited 2022 Apr 11]. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/dengue-and-severe-dengue"},{"key":"key-10.3201\/eid2905.221226-202304111246-R2","doi-asserted-by":"publisher","first-page":"S19","DOI":"10.1590\/S0102-311X2009001300003","article-title":"Dengue in the Americas: challenges for prevention and control.","volume":"25","author":"G\u00f3mez-Dant\u00e9s","year":"2009","journal-title":"Cad Saude Publica"},{"key":"key-10.3201\/eid2905.221226-202304111246-R3","doi-asserted-by":"publisher","first-page":"e903","DOI":"10.1371\/journal.pntd.0000903","article-title":"Dengue incidence in urban and rural Cambodia: results from population-based active fever surveillance, 2006-2008.","volume":"4","author":"Vong","year":"2010","journal-title":"PLoS Negl Trop Dis"},{"key":"key-10.3201\/eid2905.221226-202304111246-R4","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1186\/s12889-016-3496-9","article-title":"Rural-urban comparisons of dengue seroprevalence in Malaysia.","volume":"16","author":"Chew","year":"2016","journal-title":"BMC Public Health"},{"key":"key-10.3201\/eid2905.221226-202304111246-R5","doi-asserted-by":"publisher","first-page":"517","DOI":"10.4269\/ajtmh.14-0772","article-title":"Causes of fever in rural southern Laos.","volume":"93","author":"Mayxay","year":"2015","journal-title":"Am J Trop Med Hyg"},{"key":"key-10.3201\/eid2905.221226-202304111246-R6","doi-asserted-by":"publisher","first-page":"e0006425","DOI":"10.1371\/journal.pntd.0006425","article-title":"Data quality and timeliness of outbreak reporting system among countries in Greater Mekong subregion: Challenges for international data sharing.","volume":"12","author":"Lawpoolsri","year":"2018","journal-title":"PLoS Negl Trop Dis"},{"key":"key-10.3201\/eid2905.221226-202304111246-R7","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.4269\/ajtmh.14-0588","article-title":"2013 dengue outbreaks in Singapore and Malaysia caused by different viral strains.","volume":"92","author":"Ng","year":"2015","journal-title":"Am J Trop Med Hyg"},{"key":"key-10.3201\/eid2905.221226-202304111246-R8","unstructured":"National Environmental Agency. Surveillance and Epidemiology Programme [cited 2022 Jun 10]. https:\/\/www.nea.gov.sg\/corporate-functions\/resources\/research\/surveillance-and-epidemiology-programme"},{"key":"key-10.3201\/eid2905.221226-202304111246-R9","doi-asserted-by":"publisher","first-page":"29","DOI":"10.15381\/anales.v78i1.13018","article-title":"Evolution of dengue virus in Ecuador 2000\u20132015","volume":"78","author":"Real","year":"2017","journal-title":"An Fac Med (Per\u00fa)"},{"key":"key-10.3201\/eid2905.221226-202304111246-R10","doi-asserted-by":"publisher","first-page":"1642","DOI":"10.3201\/eid1910.130137","article-title":"Transition in the cause of fever from malaria to dengue, Northwestern Ecuador, 1990-2011.","volume":"19","author":"Cifuentes","year":"2013","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2905.221226-202304111246-R11","unstructured":"World Health Organization. Geographical expansion of cases of dengue and chikungunya beyond the historical areas of transmission in the Region of the Americas [cited 2023 Apr 3]. https:\/\/www.who.int\/emergencies\/disease-outbreak-news\/item\/2023-DON448"},{"key":"key-10.3201\/eid2905.221226-202304111246-R12","doi-asserted-by":"publisher","first-page":"101656","DOI":"10.1016\/j.tmaid.2020.101656","article-title":"COVID-19 and dengue, co-epidemics in Ecuador and other countries in Latin America: Pushing strained health care systems over the edge.","volume":"37","author":"Navarro","year":"2020","journal-title":"Travel Med Infect Dis"},{"key":"key-10.3201\/eid2905.221226-202304111246-R13","doi-asserted-by":"crossref","unstructured":"M\u00e1rquez S, Carrera J, Esp\u00edn E, Cifuentes S, Trueba G, Coloma J,  Dengue serotype differences in urban and semi-rural communities in Ecuador. ACI Avances en Ciencias e Ingenier\u00edas. 2018 [cited 2022 Jan 12]. https:\/\/revistas.usfq.edu.ec\/index.php\/avances\/article\/view\/959","DOI":"10.18272\/aci.v10i1.959"},{"key":"key-10.3201\/eid2905.221226-202304111246-R14","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.3201\/eid2207.160326","article-title":"Single-reaction multiplex reverse transcription PCR for detection of Zika, chikungunya, and dengue viruses.","volume":"22","author":"Waggoner","year":"2016","journal-title":"Emerg Infect Dis"},{"key":"key-10.3201\/eid2905.221226-202304111246-R15","doi-asserted-by":"publisher","first-page":"2634","DOI":"10.1128\/JCM.36.9.2634-2639.1998","article-title":"Typing of dengue viruses in clinical specimens and mosquitoes by single-tube multiplex reverse transcriptase PCR.","volume":"36","author":"Harris","year":"1998","journal-title":"J Clin Microbiol"},{"key":"key-10.3201\/eid2905.221226-202304111246-R16","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1038\/nprot.2017.066","article-title":"Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples.","volume":"12","author":"Quick","year":"2017","journal-title":"Nat Protoc"},{"key":"key-10.3201\/eid2905.221226-202304111246-R17","doi-asserted-by":"publisher","first-page":"3552","DOI":"10.1093\/bioinformatics\/btaa145","article-title":"Genome Detective Coronavirus Typing Tool for rapid identification and characterization of novel coronavirus genomes.","volume":"36","author":"Cleemput","year":"2020","journal-title":"Bioinformatics"},{"key":"key-10.3201\/eid2905.221226-202304111246-R18","doi-asserted-by":"publisher","first-page":"vew007","DOI":"10.1093\/ve\/vew007","article-title":"Exploring the temporal structure of heterochronous sequences using TempEst (formerly Path-O-Gen).","volume":"2","author":"Rambaut","year":"2016","journal-title":"Virus Evol"},{"key":"key-10.3201\/eid2905.221226-202304111246-R19","doi-asserted-by":"publisher","first-page":"e88","DOI":"10.1371\/journal.pbio.0040088","article-title":"Relaxed phylogenetics and dating with confidence.","volume":"4","author":"Drummond","year":"2006","journal-title":"PLoS Biol"},{"key":"key-10.3201\/eid2905.221226-202304111246-R20","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1093\/molbev\/msi103","article-title":"Bayesian coalescent inference of past population dynamics from molecular sequences.","volume":"22","author":"Drummond","year":"2005","journal-title":"Mol Biol Evol"},{"key":"key-10.3201\/eid2905.221226-202304111246-R21","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1093\/sysbio\/syy032","article-title":"Posterior summarization in Bayesian phylogenetics using Tracer 1.7.","volume":"67","author":"Rambaut","year":"2018","journal-title":"Syst Biol"},{"key":"key-10.3201\/eid2905.221226-202304111246-R22","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.4269\/ajtmh.22-0296","article-title":"A chikungunya outbreak in a dengue-endemic region in rural northern coastal Ecuador.","volume":"107","author":"M\u00e1rquez","year":"2022","journal-title":"Am J Trop Med Hyg"},{"key":"key-10.3201\/eid2905.221226-202304111246-R23","doi-asserted-by":"crossref","unstructured":"Allicock OM, Sahadeo N, Lemey P, Auguste AJ, Suchard MA, Rambaut A,  Determinants of dengue virus dispersal in the Americas. Virus Evol. 2020;6:veaa074.","DOI":"10.1093\/ve\/veaa074"},{"key":"key-10.3201\/eid2905.221226-202304111246-R24","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1186\/s13071-019-3837-5","article-title":"Active dispersal of Aedes albopictus: a mark-release-recapture study using self-marking units.","volume":"12","author":"Vavassori","year":"2019","journal-title":"Parasit Vectors"},{"key":"key-10.3201\/eid2905.221226-202304111246-R25","doi-asserted-by":"publisher","first-page":"15123","DOI":"10.1128\/JVI.79.24.15123-15130.2005","article-title":"Clade replacements in dengue virus serotypes 1 and 3 are associated with changing serotype prevalence.","volume":"79","author":"Zhang","year":"2005","journal-title":"J Virol"},{"key":"key-10.3201\/eid2905.221226-202304111246-R26","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.1007\/s00705-010-0721-1","article-title":"Evolution of dengue virus in Mexico is characterized by frequent lineage replacement.","volume":"155","author":"Carrillo-Valenzo","year":"2010","journal-title":"Arch Virol"},{"key":"key-10.3201\/eid2905.221226-202304111246-R27","doi-asserted-by":"publisher","first-page":"3","DOI":"10.2149\/tmh.2011-S05","article-title":"Dengue, urbanization and globalization: the unholy trinity of the 21(st) century.","volume":"39","author":"Gubler","year":"2011","journal-title":"Trop Med Health"},{"key":"key-10.3201\/eid2905.221226-202304111246-R28","doi-asserted-by":"publisher","first-page":"e0006070","DOI":"10.1371\/journal.pntd.0006070","article-title":"The introduction of dengue follows transportation infrastructure changes in the state of Acre, Brazil: A network-based analysis.","volume":"11","author":"Lana","year":"2017","journal-title":"PLoS Negl Trop Dis"},{"key":"key-10.3201\/eid2905.221226-202304111246-R29","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1016\/j.scitotenv.2017.04.050","article-title":"Ascertaining the impact of public rapid transit system on spread of dengue in urban settings.","volume":"598","author":"Sanna","year":"2017","journal-title":"Sci Total Environ"},{"key":"key-10.3201\/eid2905.221226-202304111246-R30","doi-asserted-by":"publisher","first-page":"e0007350","DOI":"10.1371\/journal.pntd.0007350","article-title":"Urban villages as transfer stations for dengue fever epidemic: A case study in the Guangzhou, China.","volume":"13","author":"Ren","year":"2019","journal-title":"PLoS Negl Trop Dis"},{"key":"key-10.3201\/eid2905.221226-202304111246-R31","doi-asserted-by":"publisher","first-page":"e209","DOI":"10.1016\/S2352-3018(19)30407-2","article-title":"HIV transmission and source-sink dynamics in sub-Saharan Africa.","volume":"7","author":"Okano","year":"2020","journal-title":"Lancet HIV"},{"key":"key-10.3201\/eid2905.221226-202304111246-R32","unstructured":"Ecuadorian Ministry of Public Health. Weekly epidemiological gazette No 47. 2014 [cited 2022 Apr 13]. https:\/\/www.salud.gob.ec\/wp-content\/uploads\/downloads\/2014\/12\/Gaceta-N-47_opt.pdf"},{"key":"key-10.3201\/eid2905.221226-202304111246-R33","unstructured":"Ecuadorian Ministry of Public Health. Vector gazette N\u00b052, 2019. 2019 [cited 2022 Apr 13]. https:\/\/www.salud.gob.ec\/wp-content\/uploads\/2020\/02\/GACETA-VECTORES-SE-52.pdf"},{"key":"key-10.3201\/eid2905.221226-202304111246-R34","doi-asserted-by":"publisher","first-page":"e190423","DOI":"10.1590\/0074-02760190423","article-title":"Genomic detection of a virus lineage replacement event of dengue virus serotype 2 in Brazil, 2019.","volume":"115","author":"de Jesus","year":"2020","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"key-10.3201\/eid2905.221226-202304111246-R35","doi-asserted-by":"publisher","first-page":"103977","DOI":"10.1016\/j.meegid.2019.103977","article-title":"Genotype replacement of dengue virus type 3 and clade replacement of dengue virus type 2 genotype Cosmopolitan in Dhaka, Bangladesh in 2017.","volume":"75","author":"Suzuki","year":"2019","journal-title":"Infect Genet Evol"},{"key":"key-10.3201\/eid2905.221226-202304111246-R36","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/S1567-1348(03)00004-2","article-title":"The origin, emergence and evolutionary genetics of dengue virus.","volume":"3","author":"Holmes","year":"2003","journal-title":"Infect Genet Evol"},{"key":"key-10.3201\/eid2905.221226-202304111246-R37","doi-asserted-by":"publisher","first-page":"108226","DOI":"10.1016\/j.celrep.2020.108226","article-title":"Antigenic variation of the dengue virus 2 genotypes impacts the neutralization activity of human antibodies in vaccinees.","volume":"33","author":"Martinez","year":"2020","journal-title":"Cell Rep"},{"key":"key-10.3201\/eid2905.221226-202304111246-R38","doi-asserted-by":"publisher","first-page":"e0006827","DOI":"10.1371\/journal.pntd.0006827","article-title":"Inter- and intra-host sequence diversity reveal the emergence of viral variants during an overwintering epidemic caused by dengue virus serotype 2 in southern Taiwan.","volume":"12","author":"Ko","year":"2018","journal-title":"PLoS Negl Trop Dis"},{"key":"key-10.3201\/eid2905.221226-202304111246-R39","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1186\/s12862-020-1596-8","article-title":"The origins of dengue and chikungunya viruses in Ecuador following increased migration from Venezuela and Colombia.","volume":"20","author":"Maljkovic Berry","year":"2020","journal-title":"BMC Evol Biol"},{"key":"key-10.3201\/eid2905.221226-202304111246-R40","doi-asserted-by":"publisher","first-page":"6941735","DOI":"10.1155\/2018\/6941735","article-title":"Revisiting key entry routes of human epidemic arboviruses into the mainland Americas through large-scale phylogenomics.","volume":"2018","author":"Campos","year":"2018","journal-title":"Int J Genomics"},{"key":"key-10.3201\/eid2905.221226-202304111246-R41","unstructured":"Blouin C. After the arrival: realities of Venezuelan migration. Lima: Pontificial Catholic University of Peru, Institute of Democracy and Human Rights (IDEHPUCP); 2019."},{"key":"key-10.3201\/eid2905.221226-202304111246-R42","doi-asserted-by":"publisher","first-page":"e0252379","DOI":"10.1371\/journal.pone.0252379","article-title":"Phylogenetic and evolutionary analysis of dengue virus serotypes circulating at the Colombian-Venezuelan border during 2015-2016 and 2018-2019.","volume":"16","author":"Carrillo-Hernandez","year":"2021","journal-title":"PLoS One"},{"key":"key-10.3201\/eid2905.221226-202304111246-R43","doi-asserted-by":"publisher","first-page":"317","DOI":"10.3389\/fcimb.2017.00317","article-title":"Global epidemiology of dengue outbreaks in 1990-2015: a systematic review and meta-analysis.","volume":"7","author":"Guo","year":"2017","journal-title":"Front Cell Infect Microbiol"}],"container-title":["Emerging Infectious Diseases"],"original-title":[],"link":[{"URL":"https:\/\/wwwnc.cdc.gov\/eid\/article\/29\/5\/22-1226_article","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,30]],"date-time":"2024-11-30T17:59:03Z","timestamp":1732989543000},"score":1,"resource":{"primary":{"URL":"https:\/\/wwwnc.cdc.gov\/eid\/article\/29\/5\/22-1226_article.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":43,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"URL":"https:\/\/doi.org\/10.3201\/eid2905.221226","relation":{},"ISSN":["1080-6040","1080-6059"],"issn-type":[{"value":"1080-6040","type":"print"},{"value":"1080-6059","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5]]}}}