{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T20:57:17Z","timestamp":1781729837749,"version":"3.54.5"},"reference-count":15,"publisher":"Centers for Disease Control and Prevention (CDC)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Emerg. Infect. Dis."],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.3201\/eid3207.260388","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T20:44:24Z","timestamp":1781729064000},"source":"Crossref","is-referenced-by-count":0,"title":["Vascularized Iris Mass as Sentinel Manifestation of Syphilis in Patient with HIV Infection, Spain, 2025"],"prefix":"10.3201","volume":"32","author":[{"given":"Marta","family":"Caminal-Caram\u00e9s","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaume","family":"S\u00e1nchez-Serra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesus","family":"D\u00edaz-Cascajosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Saladrigas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Conversa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Ignacio","family":"Vela-Segarra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1822","reference":[{"key":"key-10.3201\/eid3207.260388-202606171644-R1","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.ajo.2025.05.048","article-title":"Incidence and prevalence of syphilitic uveitis and associated ocular complications in the TriNetX database.","volume":"277","author":"Zhou","year":"2025","journal-title":"Am J Ophthalmol"},{"key":"key-10.3201\/eid3207.260388-202606171644-R2","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/s12348-015-0056-x","article-title":"Clinical and laboratory characteristics of ocular syphilis: a new face in the era of HIV co-infection.","volume":"5","author":"Lee","year":"2015","journal-title":"J Ophthalmic Inflamm Infect"},{"key":"key-10.3201\/eid3207.260388-202606171644-R3","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1111\/j.1442-9071.2010.02203.x","article-title":"Syphilitic uveitis: a review of clinical manifestations and treatment outcomes of syphilitic uveitis in human immunodeficiency virus-positive and negative patients.","volume":"38","author":"Amaratunge","year":"2010","journal-title":"Clin Exp Ophthalmol"},{"key":"key-10.3201\/eid3207.260388-202606171644-R4","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.jcjo.2021.01.006","article-title":"The many faces of ocular syphilis: case-based update on recognition, diagnosis, and treatment.","volume":"56","author":"Schulz","year":"2021","journal-title":"Can J Ophthalmol"},{"key":"key-10.3201\/eid3207.260388-202606171644-R5","doi-asserted-by":"publisher","first-page":"1648","DOI":"10.1080\/09273948.2023.2276298","article-title":"A vascularized iris mass in ocular syphilis: a case report and review of literature.","volume":"32","author":"Rosenberg","year":"2024","journal-title":"Ocul Immunol Inflamm"},{"key":"key-10.3201\/eid3207.260388-202606171644-R6","doi-asserted-by":"publisher","first-page":"101858","DOI":"10.1016\/j.ajoc.2023.101858","article-title":"A vascular syphilitic iris lesion.","volume":"31","author":"Chen","year":"2023","journal-title":"Am J Ophthalmol Case Rep"},{"key":"key-10.3201\/eid3207.260388-202606171644-R7","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/S1473-3099(17)30071-3","article-title":"A translucent vascularised iris granuloma in a patient with secondary syphilis.","volume":"17","author":"de Jong","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"key-10.3201\/eid3207.260388-202606171644-R8","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1001\/jamaophthalmol.2017.5560","article-title":"Uveal mass, uveitis, and diffuse rash in a woman in her 50s.","volume":"136","author":"Michaelov","year":"2018","journal-title":"JAMA Ophthalmol"},{"key":"key-10.3201\/eid3207.260388-202606171644-R9","doi-asserted-by":"publisher","first-page":"1906","DOI":"10.1097\/IAE.0b013e3182509796","article-title":"Ocular manifestations of syphilitic uveitis in Chinese patients.","volume":"32","author":"Yang","year":"2012","journal-title":"Retina"},{"key":"key-10.3201\/eid3207.260388-202606171644-R10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.15585\/mmwr.rr7004a1","article-title":"Sexually transmitted infections treatment guidelines, 2021.","volume":"70","author":"Workowski","year":"2021","journal-title":"MMWR Recomm Rep"},{"key":"key-10.3201\/eid3207.260388-202606171644-R11","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/s12348-025-00488-4","article-title":"Diagnostic riddle\u2014case report of ocular syphilis.","volume":"15","author":"Boci\u0105ga-Ko\u017cuch","year":"2025","journal-title":"J Ophthalmic Inflamm Infect"},{"key":"key-10.3201\/eid3207.260388-202606171644-R12","doi-asserted-by":"publisher","first-page":"448.e21","DOI":"10.1016\/j.amjmed.2005.11.016","article-title":"Ocular syphilis in HIV-positive patients receiving highly active antiretroviral therapy.","volume":"119","author":"Balba","year":"2006","journal-title":"Am J Med"},{"key":"key-10.3201\/eid3207.260388-202606171644-R13","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1097\/DAD.0b013e3181e8b587","article-title":"The immunopathobiology of syphilis: the manifestations and course of syphilis are determined by the level of delayed-type hypersensitivity.","volume":"33","author":"Carlson","year":"2011","journal-title":"Am J Dermatopathol"},{"key":"key-10.3201\/eid3207.260388-202606171644-R14","doi-asserted-by":"publisher","first-page":"44","DOI":"10.12746\/swrccc.v9i41.931","article-title":"A case of ocular neurosyphilis in a patient with HIV.","volume":"9","author":"Tasnim","year":"2021","journal-title":"Southwest Respir Crit Care Chron."},{"key":"key-10.3201\/eid3207.260388-202606171644-R15","unstructured":"Moshirfar M, Rageh A, Ronquillo Y. Benign and malignant iris tumors. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024."}],"container-title":["Emerging Infectious Diseases"],"original-title":[],"deposited":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T20:44:24Z","timestamp":1781729064000},"score":1,"resource":{"primary":{"URL":"https:\/\/wwwnc.cdc.gov\/eid\/article\/32\/7\/26-0388_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"URL":"https:\/\/doi.org\/10.3201\/eid3207.260388","relation":{},"ISSN":["1080-6040","1080-6059"],"issn-type":[{"value":"1080-6040","type":"print"},{"value":"1080-6059","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]}}}