{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T05:16:59Z","timestamp":1740028619908,"version":"3.37.3"},"reference-count":0,"publisher":"IOS Press","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>A novel approach to scientific investigations, besides analysis of individual phenomena, integrates different, interdisciplinary sources of knowledge about a complex system to obtain an understanding of the system as a whole. This innovative way of research called system-level science, requires advanced methods and tools for enabling collaboration of research groups. This paper presents a new approach to development and execution of collaborative applications. These applications are built as experiment plans with a notation based on the Ruby language. The virtual laboratory, which is an integrated system of dedicated tools and servers, provides a common space for planning, building, improving and performing in-silico experiments by a group of developers. The application is built with elements called gems which are available on the distributed Web- and Grid-based infrastructure. The process of application developments and the functionality of the virtual laboratory are demonstrated with a real-life example of the drug susceptibility ranking application from the HIV treatment domain.<\/jats:p>","DOI":"10.3233\/978-1-60750-073-5-299","type":"book-chapter","created":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T15:30:51Z","timestamp":1739979051000},"source":"Crossref","is-referenced-by-count":0,"title":["Building Collaborative Applications for System-level Science"],"prefix":"10.3233","author":[{"family":"Bubak Marian","sequence":"additional","affiliation":[]},{"family":"Guba&lstrok;a Tomasz","sequence":"additional","affiliation":[]},{"family":"Kasztelnik Marek","sequence":"additional","affiliation":[]},{"family":"Malawski Maciej","sequence":"additional","affiliation":[]}],"member":"7437","container-title":["Advances in Parallel Computing","High Speed and Large Scale Scientific Computing"],"original-title":[],"deposited":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T15:49:10Z","timestamp":1739980150000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medra.org\/servlet\/aliasResolver?alias=iospressISSNISBN&issn=0927-5452&volume=18&spage=299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/978-1-60750-073-5-299","relation":{},"ISSN":["0927-5452"],"issn-type":[{"value":"0927-5452","type":"print"}],"subject":[],"published":{"date-parts":[[2009]]}}}