{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T00:10:47Z","timestamp":1740269447785,"version":"3.37.3"},"reference-count":0,"publisher":"IOS Press","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2001]]},"abstract":"<jats:p>Objective: To characterize the relationships among UMLS concepts that co-occur as MeSH descriptors in MEDLINE citations (1990-1999). Design: 18,485 UMLS concepts involved in 7,928,608 directed pairs of co-occurring concepts were studied. For each directed pair of concepts Cl-C2: (i) the &amp;ldquo;family&amp;rdquo; of Cl was built, using the UMLS Metathesaurus, and we tested whether or not C2 belonged to Cl&amp;apos;s family; (ii) we used the semantic categorization of Metathesaurus concepts through the UMLS Semantic Network and Semantic Groups to represent the semantics of the relationships between Cl and C2. Results: In 6.5% of the directed pairs, the co-occurring concept C2 was found within the &amp;ldquo;family&amp;rdquo; of Cl. Detailed results are given. The most frequent co-occurrences involved &amp;ldquo;Chemicals &amp;amp; Drugs&amp;rdquo; and &amp;ldquo;Chemicals &amp;amp; Drugs&amp;rdquo;, as well as &amp;ldquo;Disorders&amp;rdquo; and &amp;ldquo;Chemicals &amp;amp; Drugs&amp;rdquo;. Discussion: This work takes advantage of both symbolic and statistical information represented in the UMLS, and analyzes their overlap. Further research is suggested.<\/jats:p>","DOI":"10.3233\/978-1-60750-928-8-171","type":"book-chapter","created":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T23:19:26Z","timestamp":1740266366000},"source":"Crossref","is-referenced-by-count":0,"title":["Methods for Exploring the Semantics of the Relationships between Co-occurring UMLS Concepts"],"prefix":"10.3233","author":[{"family":"Burgun Anita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Bodenreider Olivier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","MEDINFO 2001"],"original-title":[],"deposited":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T23:36:22Z","timestamp":1740267382000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medra.org\/servlet\/aliasResolver?alias=iospressISSNISBN&issn=0926-9630&volume=84&spage=171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001]]},"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/978-1-60750-928-8-171","relation":{},"ISSN":["0926-9630"],"issn-type":[{"value":"0926-9630","type":"print"}],"subject":[],"published":{"date-parts":[[2001]]}}}