{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T05:15:56Z","timestamp":1740287756949,"version":"3.37.3"},"reference-count":0,"publisher":"IOS Press","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004]]},"abstract":"<jats:p>Background: Pharmacovigilance experts detect new adverse drug reactions (ADR) by manually reviewing spontaneous reporting systems. Automated signal generation aims to focus the attention of experts on drug &amp;ndash; adverse event associations which are disproportionally present in the database. Although adverse events are coded by means of controlled vocabularies such as the MedDRA dictionary, this semantic information is not taken into account for signal generation.<\/jats:p>","DOI":"10.3233\/978-1-60750-949-3-626","type":"book-chapter","created":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T23:19:26Z","timestamp":1740266366000},"source":"Crossref","is-referenced-by-count":0,"title":["A knowledge based approach for automated signal generation in pharmacovigilance"],"prefix":"10.3233","author":[{"family":"Henegar Corneliu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Bousquet C&eacute;dric","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Degoulet Patrice","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","MEDINFO 2004"],"original-title":[],"deposited":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T23:49:44Z","timestamp":1740268184000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medra.org\/servlet\/aliasResolver?alias=iospressISSNISBN&issn=0926-9630&volume=107&spage=626"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004]]},"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/978-1-60750-949-3-626","relation":{},"ISSN":["0926-9630"],"issn-type":[{"value":"0926-9630","type":"print"}],"subject":[],"published":{"date-parts":[[2004]]}}}