{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T05:33:55Z","timestamp":1740202435953,"version":"3.37.3"},"reference-count":0,"publisher":"IOS Press","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Dozens of drug terminologies and resources capture the drug and\/or drug class information, ranging from their coverage and adequacy of representation. No transformative ways are available to link them together in a standard way, which hinders data integration and data representation for drug-related clinical and translational studies. In this paper, we introduce our preliminary work for building a standardized drug and drug class network that integrates multiple drug terminological resources, using Anatomical Therapeutic Chemical (ATC) and National Drug File Reference Terminology (NDF-RT) as network backbone, and expanding with RxNorm and Structured Product Label (SPL). The network consists of 39,728 drugs and drug classes. We calculated and compared structure similarity for each drug\/drug class pair from ATC and NDF-RT, and analyzed constructed drug class network from chemical structure perspective.<\/jats:p>","DOI":"10.3233\/978-1-61499-289-9-1125","type":"book-chapter","created":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:45:03Z","timestamp":1740149103000},"source":"Crossref","is-referenced-by-count":0,"title":["Standardized Drug and Pharmacological Class Network Construction"],"prefix":"10.3233","author":[{"family":"Zhu Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Jiang Guoqian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Wang Liwei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Chute Christopher G.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","MEDINFO 2013"],"original-title":[],"deposited":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T15:22:25Z","timestamp":1740151345000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medra.org\/servlet\/aliasResolver?alias=iospressISSNISBN&issn=0926-9630&volume=192&spage=1125"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/978-1-61499-289-9-1125","relation":{},"ISSN":["0926-9630"],"issn-type":[{"value":"0926-9630","type":"print"}],"subject":[],"published":{"date-parts":[[2013]]}}}