{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,22]],"date-time":"2025-02-22T05:22:00Z","timestamp":1740201720530,"version":"3.37.3"},"reference-count":0,"publisher":"IOS Press","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>Introduction: Since the late 1990s, research and administrative institutions have been developing health data warehouses and increasingly reusing claims data. The impact of these changes is not yet completely quantified. Our objective was to compare the change in the number of patients included per study between observational and interventional studies over a 20-year period starting in 1995.<\/jats:p>","DOI":"10.3233\/978-1-61499-921-8-50","type":"book-chapter","created":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:25:19Z","timestamp":1740126319000},"source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Changes in the Number of Included Patients Between Interventional Trials and Observational Studies Published from 1995 to 2014 in Three Leading Journals"],"prefix":"10.3233","author":[{"family":"Dezetree Arnaud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Chazard Emmanuel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Schlegel Daniel R.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Sakilay Sylvester","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Elkin Peter L.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Ficheur Gr&eacute;goire","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","Decision Support Systems and Education"],"original-title":[],"deposited":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:34:11Z","timestamp":1740126851000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.medra.org\/servlet\/aliasResolver?alias=iospressISBN&isbn=978-1-61499-920-1&spage=50&doi=10.3233\/978-1-61499-921-8-50"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/978-1-61499-921-8-50","relation":{},"ISSN":["0926-9630"],"issn-type":[{"value":"0926-9630","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]}}}