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The approach has been applied to large datasets that include country level medical and the socio-economic data according to World Health Organization, the role of the cigarette consumption per capita using open datasets, and the cumulative data of the \u201cCOVID-19 Data Repository by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University\u201d for the total number of Cases, Deaths and Recovered. 101 countries including twenty-two (22) features are studied. We have also drilled in the country of Mexico datasets to show case the effectiveness of our approach. We show that our approach can achieve 96% overall accuracy based on the proposed combination approach of macro and micro features. Our approach outdoes previous study results that utilize machine learning to assist medical decision-making in COVID-19 prognosis. We conclude that country social economic and medical characteristics play important role to COVID-19 patients\u2019 prognosis and their outcome.<\/jats:p>","DOI":"10.3233\/idt-210061","type":"journal-article","created":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T12:10:29Z","timestamp":1647346229000},"page":"231-245","source":"Crossref","is-referenced-by-count":0,"title":["Exploring the role of country social and medical characteristics in patient level mortality in COVID-19 pandemic using Unsupervised Learning"],"prefix":"10.1177","volume":"16","author":[{"given":"George","family":"Varelas","sequence":"first","affiliation":[{"name":"Department of Electrical and Computer Engineering, University of Peloponnese, Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelos","family":"Sakkopoulos","sequence":"additional","affiliation":[{"name":"Department of Informatics, School of Information and Communication Technologies, University of Piraeus, Piraeus, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giannis","family":"Tzimas","sequence":"additional","affiliation":[{"name":"Department of Electrical and Computer Engineering, University of Peloponnese, Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"10.3233\/IDT-210061_ref3","doi-asserted-by":"publisher","DOI":"10.18564\/jasss.4298"},{"key":"10.3233\/IDT-210061_ref4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003018"},{"key":"10.3233\/IDT-210061_ref5","doi-asserted-by":"crossref","unstructured":"Sharma A, Shukla A, Tiwari R, Mishra A. 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