{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:17:13Z","timestamp":1770747433174,"version":"3.49.0"},"reference-count":88,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2015,7,29]],"date-time":"2015-07-29T00:00:00Z","timestamp":1438128000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Intelligent &amp; Fuzzy Systems"],"published-print":{"date-parts":[[2015,7,29]]},"abstract":"<jats:p>\n                    Bioinformatics is a relatively new discipline where Mathematics are applied in the analysis of genetic sequences. The analysis of the genetic material of living organisms which consist of nucleic acids DNA and RNA is of great importance for diagnosis and taxonomy reasons. In the present paper we propose a new methodology for the representation of genetic sequences as fuzzy sets in the\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>12<\/jats:sup>\n                    space which can significantly improve the results of Sadegh-Zadeh and Torres &amp; Nieto. An important characteristic of our proposed methodology is that the location of Amino acids along the genetic sequences play an important role thus extending in a significant way the computational efficiency advantage of genetic sequence representation. We present some characteristic examples using the new proposed methodology where we calculate the distance and similarity degree of given polynucleotides.\n                  <\/jats:p>","DOI":"10.3233\/ifs-151701","type":"journal-article","created":{"date-parts":[[2015,11,10]],"date-time":"2015-11-10T11:37:42Z","timestamp":1447155462000},"page":"2259-2269","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["An extension of fuzzy topological approach for comparison of genetic sequences"],"prefix":"10.1177","volume":"29","author":[{"given":"DN","family":"Georgiou","sequence":"first","affiliation":[{"name":"Department of Mathematics, University of Patras, Patras, Greece"}]},{"given":"TE","family":"Karakasidis","sequence":"additional","affiliation":[{"name":"Department of Civil Engineering, University of Thessaly, Volos, Greece"}]},{"given":"AC","family":"Megaritis","sequence":"additional","affiliation":[{"name":"Technological Educational Institute of Western Greece, Department of Accounting and Finance, Messolonghi, Greece"}]},{"given":"Juan J.","family":"Nieto","sequence":"additional","affiliation":[{"name":"Departamento de An\u00e1lisis Matem\u00e1tico, Facultad de Matem\u00e1ticas, Universidad de Santiago de Compostela, Spain"}]},{"given":"A","family":"Torres","sequence":"additional","affiliation":[{"name":"Departamento de Psiquiatr\u00eda Radiolog\u00eda y Salud P\u00fablica, Facultad de Medicina, Universidad de Santiago de Compostela, Spain"}]}],"member":"179","published-online":{"date-parts":[[2015,8,21]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.123638.111"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2006.07.022"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2006.06.025"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2007.05.019"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2006.11.010"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0047843"},{"key":"e_1_3_1_8_2","doi-asserted-by":"crossref","unstructured":"Chen YK Li KB 2013 Predicting membrane protein types by incorporating protein topology domains signal peptides and physicochemical properties into the general form of Chou\u2019s pseudo amino acid composition ournal of Theoretical Biology 318 1 12","DOI":"10.1016\/j.jtbi.2012.10.033"},{"key":"e_1_3_1_9_2","doi-asserted-by":"crossref","unstructured":"K. Chou Prediction of protein cellular attributes using pseudoamino acid composition Proteins\u016eUStructure Function and Genetics 43 (2001) 246\u2013255. (Erratum: Prediction of protein cellular attributes using pseudo amino acid composition Proteins U\u016e Structure Function and Genetics 44 p. 60).","DOI":"10.1002\/prot.1035"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bth466"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/prot.10500"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1110\/ps.04981104"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2005.10.196"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/pr060167c"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1021\/pr060635i"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2007.07.006"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.21096"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.06.027"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.03.162"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2007.494"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-218X(98)00066-3"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0019-9958(72)90199-4"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.2174\/092986607781483778"},{"key":"e_1_3_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-9659(03)90000-0"},{"key":"e_1_3_1_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.aml.2004.06.011"},{"key":"e_1_3_1_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-7-518"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms15033495"},{"key":"e_1_3_1_28_2","unstructured":"Engelking R 1977 General Topology Warszawa"},{"key":"e_1_3_1_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0114(01)00127-0"},{"key":"e_1_3_1_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2012.03.017"},{"key":"e_1_3_1_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2005.06.075"},{"key":"e_1_3_1_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2013.05.024"},{"key":"e_1_3_1_33_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/15.1.89"},{"key":"e_1_3_1_34_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-med-051010-162644"},{"key":"e_1_3_1_35_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/15.12.994"},{"key":"e_1_3_1_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-6080(97)00149-4"},{"key":"e_1_3_1_37_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/17.3.286"},{"key":"e_1_3_1_38_2","doi-asserted-by":"publisher","DOI":"10.1089\/10665270252935511"},{"key":"e_1_3_1_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2010.10.037"},{"key":"e_1_3_1_40_2","unstructured":"Kosko B 1992 Neural Networks and Fuzzy Systems Prentice-Hall Englewood Cliffs NJ"},{"key":"e_1_3_1_41_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10142-015-0433-4"},{"key":"e_1_3_1_42_2","doi-asserted-by":"publisher","DOI":"10.1089\/106652701300099092"},{"key":"e_1_3_1_43_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/17.2.149"},{"key":"e_1_3_1_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiolchem.2003.10.002"},{"key":"e_1_3_1_45_2","unstructured":"Lin CT 1997 Adaptive subsethood for radial basis fuzzy systems Kosko B 429 464 Fuzzy Engineering Prentice-Hall Upper Saddle River NJ"},{"key":"e_1_3_1_46_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20554"},{"key":"e_1_3_1_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.01.011"},{"key":"e_1_3_1_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2005.08.160"},{"key":"e_1_3_1_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bulm.2004.10.005"},{"key":"e_1_3_1_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2006.06.014"},{"key":"e_1_3_1_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-9659(01)00085-4"},{"key":"e_1_3_1_52_2","doi-asserted-by":"publisher","DOI":"10.1089\/10665270050081522"},{"key":"e_1_3_1_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.patrec.2007.04.001"},{"key":"e_1_3_1_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-9659(03)90131-5"},{"key":"e_1_3_1_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0933-3657(02)00080-5"},{"key":"e_1_3_1_56_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11538-005-9020-5"},{"key":"e_1_3_1_57_2","doi-asserted-by":"crossref","unstructured":"Paun Gh Rozenberg G Saloma A 1998 DNA Computing: New Computing Paradigms Springer Berlin","DOI":"10.1007\/978-3-662-03563-4"},{"key":"e_1_3_1_58_2","doi-asserted-by":"crossref","unstructured":"Percus J 2002 Mathematics of Genome Analysis Gambridge University Press Cambridge","DOI":"10.1017\/CBO9780511613197"},{"key":"e_1_3_1_59_2","doi-asserted-by":"publisher","DOI":"10.1002\/qua.24383"},{"key":"e_1_3_1_60_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms15021746"},{"key":"e_1_3_1_61_2","first-page":"2471","article-title":"Multi-fuzzy sets","volume":"50","author":"Sebastian Sabu","year":"2010","unstructured":"Sebastian Sabu, Ramakrishnan TV 2010 Multi-fuzzy sets Int Math Forum 50 2471 2476","journal-title":"Int Math Forum"},{"key":"e_1_3_1_62_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12543-011-0064-y"},{"key":"e_1_3_1_63_2","first-page":"117","article-title":"Multi-fuzzy topology","volume":"24","author":"Sebastian Sabu","year":"2011","unstructured":"Sebastian Sabu, Ramakrishnan TV 2011 Multi-fuzzy topology Int J Appl Math 24 117 129","journal-title":"Int J Appl Math"},{"key":"e_1_3_1_64_2","first-page":"365","article-title":"Multi-fuzzy subgroups","volume":"6","author":"Sebastian Sabu","year":"2011","unstructured":"Sebastian Sabu, Ramakrishnan TV 2011 Multi-fuzzy subgroups Int J Contemp Math Sci 6 365 372","journal-title":"Int J Contemp Math Sci"},{"key":"e_1_3_1_65_2","doi-asserted-by":"publisher","DOI":"10.1142\/S1793536911000714"},{"key":"e_1_3_1_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0933-3657(99)00015-9"},{"key":"e_1_3_1_67_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0933-3657(99)00032-9"},{"key":"e_1_3_1_68_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8240(02)00107-6"},{"key":"e_1_3_1_69_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00726-011-1106-9"},{"key":"e_1_3_1_70_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1538-7305.1948.tb01338.x"},{"key":"e_1_3_1_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2005.06.087"},{"key":"e_1_3_1_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2005.09.117"},{"key":"e_1_3_1_73_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btl170"},{"key":"e_1_3_1_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2005.08.016"},{"key":"e_1_3_1_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.02.071"},{"key":"e_1_3_1_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.09.098"},{"key":"e_1_3_1_77_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.08.140"},{"key":"e_1_3_1_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0898-1221(00)00106-1"},{"key":"e_1_3_1_79_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btg032"},{"key":"e_1_3_1_80_2","article-title":"Fuzzy logic in medicine and bioinformatics","author":"Torres A","year":"2006","unstructured":"Torres A, Nieto JJ 2006 Fuzzy logic in medicine and bioinformatics Journal of Biomedicine and Biotechnology article ID 91908","journal-title":"Journal of Biomedicine and Biotechnology"},{"key":"e_1_3_1_81_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2006.05.006"},{"key":"e_1_3_1_82_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20354"},{"key":"e_1_3_1_83_2","doi-asserted-by":"publisher","DOI":"10.1039\/C0MB00170H"},{"key":"e_1_3_1_84_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0105018"},{"key":"e_1_3_1_85_2","doi-asserted-by":"crossref","unstructured":"Zaus M 1999 Crisp and Soft Computing with Hypercubical Calculus Physica-Verlag Heideberg","DOI":"10.1007\/978-3-7908-1879-6"},{"key":"e_1_3_1_86_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms16035194"},{"key":"e_1_3_1_87_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms14048179"},{"key":"e_1_3_1_88_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2007.06.001"},{"key":"e_1_3_1_89_2","doi-asserted-by":"publisher","DOI":"10.2217\/pgs.12.211"}],"container-title":["Journal of Intelligent &amp; Fuzzy Systems"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/IFS-151701","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/IFS-151701","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/IFS-151701","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T08:19:11Z","timestamp":1770711551000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/IFS-151701"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,29]]},"references-count":88,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,7,29]]}},"alternative-id":["10.3233\/IFS-151701"],"URL":"https:\/\/doi.org\/10.3233\/ifs-151701","relation":{},"ISSN":["1064-1246","1875-8967"],"issn-type":[{"value":"1064-1246","type":"print"},{"value":"1875-8967","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,29]]}}}