{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T17:27:25Z","timestamp":1771003645667,"version":"3.50.1"},"reference-count":27,"publisher":"SAGE Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JCM"],"published-print":{"date-parts":[[2019,7,17]]},"DOI":"10.3233\/jcm-180848","type":"journal-article","created":{"date-parts":[[2018,7,24]],"date-time":"2018-07-24T19:15:34Z","timestamp":1532459734000},"page":"565-579","source":"Crossref","is-referenced-by-count":0,"title":["Combining network topology with transcriptomic data for identifying radiosensitive gene signatures"],"prefix":"10.1177","volume":"19","author":[{"given":"Qinghua","family":"Cui","sequence":"first","affiliation":[]},{"given":"Tingting","family":"Sun","sequence":"additional","affiliation":[]},{"given":"Zongyao","family":"Nie","sequence":"additional","affiliation":[]}],"member":"179","reference":[{"key":"10.3233\/JCM-180848_ref1","doi-asserted-by":"crossref","first-page":"27043","DOI":"10.1038\/srep27043","article-title":"Differences in DNA Repair Capacity, Cell Death and Transcriptional Response after Irradiation between a Radiosensitive and a Radioresistant Cell Line","author":"Borr\u00e0s-Fresneda","year":"2016","journal-title":"Scientific Reports"},{"key":"10.3233\/JCM-180848_ref2","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.3892\/ijo.2017.4107","article-title":"Prediction of radiosensitive patients with gastric cancer by developinggene signature","author":"Zhou","year":"2017","journal-title":"International Journal of Oncology"},{"issue":"1","key":"10.3233\/JCM-180848_ref3","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1186\/1471-2164-13-348","article-title":"Identification of a radiosensitivity signature using integrative metaanalysis of published microarray data for NCI-60 cancer cells","volume":"13","author":"Kim","year":"2012","journal-title":"Bmc Genomics"},{"issue":"2","key":"10.3233\/JCM-180848_ref4","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1158\/0008-5472.CAN-07-2120","article-title":"Integrating Global Gene Expression and Radiation Survival Parameters across the 60 Cell Lines of the National Cancer Institute Anticancer Drug Screen","volume":"68","author":"Amundson","year":"2008","journal-title":"Cancer Research"},{"issue":"2","key":"10.3233\/JCM-180848_ref5","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0968-4328(99)00083-9","article-title":"Radiation response of cell organelles","volume":"31","author":"Somosy","year":"2000","journal-title":"Micron"},{"issue":"6","key":"10.3233\/JCM-180848_ref6","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.3892\/ijo.2013.2114","article-title":"Network-based approaches for anticancer therapy (Review)","volume":"43","author":"Seo","year":"2013","journal-title":"Int J Oncol"},{"issue":"3","key":"10.3233\/JCM-180848_ref7","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.ijrobp.2009.12.076","article-title":"Differential gene expression profiles of radioresistant non-small-cell lung cancer cell lines established by fractionated irradiation: tumor protein p53-inducible protein 3 confers sensitivity to ionizing radiation","volume":"77","author":"Lee","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"5","key":"10.3233\/JCM-180848_ref8","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1513\/pats.201107-042ST","article-title":"International Association for the Study of Lung Cancer\/American Thoracic Society\/European Respiratory Society: International Multidisciplinary Classification of Lung Adenocarcinoma","volume":"8","author":"Travis","year":"2011","journal-title":"Proceedings of the American Thoracic Society"},{"issue":"18","key":"10.3233\/JCM-180848_ref9","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1097\/00029330-200809020-00014","article-title":"Identification of differential gene expression profiles of radioresistant lung cancer cell line established by fractionated ionizing radiation in vitro","volume":"121","author":"Xu","year":"2008","journal-title":"Chin Med J Engl"},{"issue":"2","key":"10.3233\/JCM-180848_ref10","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.ijrobp.2009.05.056","article-title":"Systems Biology Modeling of the Radiation Sensitivity Network: A Biomarker Discovery Platform","volume":"75","author":"Eschrich","year":"2009","journal-title":"International Journal of Radiation Oncology Biology Physics"},{"issue":"1","key":"10.3233\/JCM-180848_ref11","doi-asserted-by":"crossref","first-page":"195","DOI":"10.3892\/ijmm.2013.1366","article-title":"Identification of common gene networks responsive to mild hyperthermia in human cancer cells","volume":"32","author":"Kariya","year":"2013","journal-title":"International Journal of Molecular Medicine"},{"key":"10.3233\/JCM-180848_ref12","doi-asserted-by":"crossref","first-page":"D767","DOI":"10.1093\/nar\/gkn892","article-title":"Human Protein Reference Database \u2013 2009 update","volume":"37","author":"Keshava Prasad","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"10.3233\/JCM-180848_ref13","doi-asserted-by":"crossref","first-page":"D532","DOI":"10.1093\/nar\/gkp983","article-title":"MINT, the molecular interaction database: 2009 update","volume":"38","author":"Ceol","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"10.3233\/JCM-180848_ref14","doi-asserted-by":"crossref","first-page":"D525","DOI":"10.1093\/nar\/gkp878","article-title":"The IntAct molecular interaction database in 2010","volume":"38","author":"Aranda","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"10.3233\/JCM-180848_ref15","doi-asserted-by":"crossref","first-page":"D449","DOI":"10.1093\/nar\/gkh086","article-title":"The Database of Interacting Proteins: 2004 update","volume":"32","author":"Salwinski","year":"2004","journal-title":"Nucleic Acids Res"},{"issue":"5","key":"10.3233\/JCM-180848_ref16","doi-asserted-by":"crossref","first-page":"R40","DOI":"10.1186\/gb-2005-6-5-r40","article-title":"Consolidating the set of known human protein-protein interactions in preparation for large-scale mapping of the human interactome","volume":"6","author":"Ramani","year":"2005","journal-title":"Genome Biol"},{"issue":"12","key":"10.3233\/JCM-180848_ref17","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1093\/bioinformatics\/btn200","article-title":"A global pathway crosstalk network","volume":"24","author":"Li","year":"2008","journal-title":"Bioinformatics"},{"issue":"11","key":"10.3233\/JCM-180848_ref18","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res"},{"issue":"19","key":"10.3233\/JCM-180848_ref19","doi-asserted-by":"crossref","first-page":"10787","DOI":"10.1073\/pnas.191368598","article-title":"Chemosensitivity prediction by transcriptional profiling","volume":"98","author":"Staunton","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"10.3233\/JCM-180848_ref20","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1158\/1535-7163.MCT-06-0650","article-title":"Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study","volume":"6","author":"Shankavaram","year":"2007","journal-title":"Molecular Cancer Therapeutics"},{"issue":"1","key":"10.3233\/JCM-180848_ref21","doi-asserted-by":"crossref","first-page":"e30706","DOI":"10.1371\/journal.pone.0030706","article-title":"The increased expressionof integrin alpha 6 (ITGA6) enhances drug resistance in EVI1 (high) leukemia","volume":"7","author":"Yamakawa","year":"2012","journal-title":"PLoS One"},{"issue":"45","key":"10.3233\/JCM-180848_ref22","doi-asserted-by":"crossref","first-page":"31296","DOI":"10.1074\/jbc.M114.565796","article-title":"Ral GTPase down-regulation stabilizes and reactivates p53 to inhibit malignant transformation","volume":"289","author":"Tecleab","year":"2014","journal-title":"The Journal of Biological Chemistry"},{"issue":"3","key":"10.3233\/JCM-180848_ref23","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1080\/01635581.2015.1004733","article-title":"Akt Signaling Is Associated with the Berberine-Induced Apoptosis of Human Gastric Cancer Cells","volume":"67","author":"Yi","year":"2015","journal-title":"Nutrition and Cancer"},{"issue":"5","key":"10.3233\/JCM-180848_ref24","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1073\/pnas.1017063108","article-title":"Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating \u03b2-catenin","volume":"108","author":"Fiedler","year":"2011","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"1","key":"10.3233\/JCM-180848_ref25","doi-asserted-by":"crossref","first-page":"e87003","DOI":"10.1371\/journal.pone.0087003","article-title":"Regulation of MYC expression and differential JQ1 sensitivity in cancer cells","volume":"9","author":"Fowler","year":"2014","journal-title":"PLoS One"},{"key":"10.3233\/JCM-180848_ref26","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.ejmech.2014.05.063","article-title":"Discovery and characterization of novel imidazopyridine derivative CHEQ-2 as a potent CDC25 inhibitor and promising anticancer drug candidate","author":"Song","year":"2014","journal-title":"European Journal of Medicinal Chemistry"},{"issue":"3","key":"10.3233\/JCM-180848_ref27","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.clml.2013.07.008","article-title":"Cyclin D1 Amplification in Multiple Myeloma Is Associated With Multidrug Resistance Expression","author":"Sewify","year":"2014","journal-title":"Clinical Lymphoma Myeloma and Leukemia"}],"container-title":["Journal of Computational Methods in Sciences and Engineering"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/JCM-180848","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T16:32:34Z","timestamp":1771000354000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/JCM-180848"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,17]]},"references-count":27,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3233\/jcm-180848","relation":{},"ISSN":["1472-7978","1875-8983"],"issn-type":[{"value":"1472-7978","type":"print"},{"value":"1875-8983","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,17]]}}}