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The influence of culture medium which is injected regularly will suddenly increase the concentration of nutrients and toxic substances, it will suddenly increase the impact on the population. These characteristics are used to construct absorption operators, grabbing operators, hybrid operators, and toxin operators; the global optimal solution of the optimization problem can be quickly solved by these operators and the population growth changes. The simulation experiment results show that the MDO algorithm has certain advantages for solving optimization problems with higher dimensions.<\/jats:p>","DOI":"10.3233\/jifs-201828","type":"journal-article","created":{"date-parts":[[2021,1,5]],"date-time":"2021-01-05T18:10:00Z","timestamp":1609870200000},"page":"5697-5713","source":"Crossref","is-referenced-by-count":2,"title":["A microbial kinetic optimization approach"],"prefix":"10.1177","volume":"40","author":[{"given":"Xiong","family":"Ding","sequence":"first","affiliation":[{"name":"School of Information and Mechanical Engineering, Hunan International Economics University, Changsha, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Lu","sequence":"additional","affiliation":[{"name":"School of Information and Mechanical Engineering, Hunan International Economics University, Changsha, 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