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This research paper focuses on the development of a cardiovascular disease prediction system particularly a heart disease, by developing machine learning classifiers, for instance, Support Vector Machine (SVM), Decision Tree, and XGBoost Classifiers. We also scaled the features to standardize unconstrained features in data, available in a fixed range for better optimization of models. For efficiency, the classification of features was also done in two categories, Independent features, and dependent features. Furthermore, the performance measures helped with best practices for model assessment &amp; classifier performance. Eventually, after tuning hyper-parameters, the results exhibit high accuracy for XGBoost among other trained classifiers. After a comparative analysis, the best-suited algorithm can be utilized for heart disease detection, in the medical field, and regarding the economy, as costly treatments are taken into consideration. This indicates that a non-expert can also attempt for diagnosis without fretting over expensive treatments.<\/jats:p>","DOI":"10.3233\/jifs-219302","type":"journal-article","created":{"date-parts":[[2022,3,11]],"date-time":"2022-03-11T11:57:43Z","timestamp":1646999863000},"page":"2025-2033","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Big data analytics and classification of cardiovascular disease using machine learning"],"prefix":"10.1177","volume":"43","author":[{"given":"Sanam","family":"Narejo","sequence":"first","affiliation":[{"name":"Department of Computer Systems Engineering, Mehran University of Engineering &amp; Technology, Jamshoro, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anoud","family":"Shaikh","sequence":"additional","affiliation":[{"name":"Department of Software Engineering, Mehran University of Engineering &amp; Technology, Jamshoro, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehak Maqbool","family":"Memon","sequence":"additional","affiliation":[{"name":"Department of Computer &amp; Information Sciences, Universiti Teknologi PETRONAS, Seri Iskandar, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kainat","family":"Mahar","sequence":"additional","affiliation":[{"name":"Department of Computer Systems Engineering, Mehran University of Engineering &amp; Technology, Jamshoro, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zonera","family":"Aleem","sequence":"additional","affiliation":[{"name":"Department of Computer Systems Engineering, Mehran University of Engineering &amp; Technology, Jamshoro, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bisharat","family":"Zardari","sequence":"additional","affiliation":[{"name":"Department of Computer Systems Engineering, Mehran University of Engineering &amp; Technology, Jamshoro, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,3,9]]},"reference":[{"key":"e_1_3_1_2_2","unstructured":"Abdel-BassetM. 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