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In this paper, we proposed a new method for detecting the tumor with enhanced performance over traditional techniques such as K-Means Clustering, fuzzy c means (FCM). Different research methods have been proposed by researchers to detect the tumor in brain. To classify normal and abnormal form of brain, a system for screening is discussed in this paper which is developed with a framework of artificial intelligence with deep learning probabilistic neural networks by focusing on hybrid clustering for segmentation on brain image and crystal contrast enhancement. Feature\u2019s extraction and classification are included in the developing process. Performance in Simulation of proposed design has shown the superior results than the traditional methods.<\/jats:p>","DOI":"10.3233\/jifs-232493","type":"journal-article","created":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T11:01:18Z","timestamp":1690887678000},"page":"6485-6500","source":"Crossref","is-referenced-by-count":18,"title":["Brain tumor segmentation and classification with hybrid clustering, probabilistic neural networks"],"prefix":"10.1177","volume":"45","author":[{"given":"M.D.","family":"Javeed","sequence":"first","affiliation":[{"name":"Department of od ECE and Director, IQAC, Princeton Institute of Engineering and Technology for Women, Hyderabad, Telangana, India"}]},{"given":"Regonda","family":"Nagaraju","sequence":"additional","affiliation":[{"name":"Department of CSE \u2013 AI&ML, School of Engineering, Mallareddy University, Hyderabad, Telangana, India"}]},{"given":"Raja","family":"Chandrasekaran","sequence":"additional","affiliation":[{"name":"Department of ECE, Vel Tech Rangarajan Dr. Sagunthala R & D Institute of Science and Technology, Chennai, Tamil Nadu, India"}]},{"given":"Govinda","family":"Rajulu","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Design, St Martins Engineering college, Secundrabad, Telangana, India"}]},{"given":"Praveen","family":"Tumuluru","sequence":"additional","affiliation":[{"name":"Department of CSE, Koneru Lakshmaiah Education Foundation, Vaddeswaram, AP, India"}]},{"given":"M.","family":"Ramesh","sequence":"additional","affiliation":[{"name":"Department of CSE, National Institute of Technology, Goa, India"}]},{"given":"Sanjay Kumar","family":"Suman","sequence":"additional","affiliation":[{"name":"Department of ECE, and Dean R&D, St. Martin\u2019s Engineering College Secunderabad Telangana, India"}]},{"given":"Rajeev","family":"Shrivastava","sequence":"additional","affiliation":[{"name":"Princeton Institute of Engineering and Technology for Women, Hyderabad, Telangana, India"}]}],"member":"179","reference":[{"key":"10.3233\/JIFS-232493_ref1","doi-asserted-by":"publisher","first-page":"107333","DOI":"10.1109\/ACCESS.2021.3091632","article-title":"Variable Structure Based Control for the Chemotherapy of Brain Tumor","volume":"9","author":"Zubair","year":"2021","journal-title":"IEEE Access"},{"key":"10.3233\/JIFS-232493_ref2","doi-asserted-by":"publisher","first-page":"1749","DOI":"10.1109\/ICICCS51141.2021.9432235","article-title":"Brain Tumor Analysis Using Deep Neural Network","author":"Khan","year":"2021","journal-title":"2021 5th International Conference on Intelligent Computing and Control Systems (ICICCS)"},{"issue":"2","key":"10.3233\/JIFS-232493_ref3","first-page":"171","article-title":"Image Segmentation by Improved Watershed Transformation in Programming Environment MATLAB","volume":"1","author":"Bhagwatl","year":"2010","journal-title":"International Journal of Computer Science &Communication"},{"key":"10.3233\/JIFS-232493_ref4","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.asoc.2009.11.019","article-title":"Systematic image processing for diagnosing brain tumours: A Type-II fuzzy expert system approach","author":"Zarandia","year":"2011","journal-title":"Applied Soft Computing"},{"issue":"3","key":"10.3233\/JIFS-232493_ref5","first-page":"437","article-title":"An Effective Approach for Segmentation of MRI Images: Combining Spatial Information with Fuzzy C-Means Clustering","volume":"41","author":"ZulaikhaBeevi","year":"2010","journal-title":"European Journal of Scientific Research"},{"key":"10.3233\/JIFS-232493_ref6","doi-asserted-by":"crossref","unstructured":"Praveena S. 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