{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T11:33:04Z","timestamp":1775561584898,"version":"3.50.1"},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"value":"9781643683881","type":"print"},{"value":"9781643683898","type":"electronic"}],"license":[{"start":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T00:00:00Z","timestamp":1684368000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,18]]},"abstract":"<jats:p>The COVID-19 pandemic has urged the need to set up, conduct and analyze high-quality epidemiological studies within a very short time-scale to provide timely evidence on influential factors on the pandemic, e.g. COVID-19 severity and disease course. The comprehensive research infrastructure developed to run the German National Pandemic Cohort Network within the Network University Medicine is now maintained within a generic clinical epidemiology and study platform NUKLEUS. It is operated and subsequently extended to allow efficient joint planning, execution and evaluation of clinical and clinical-epidemiological studies. We aim to provide high-quality biomedical data and biospecimens and make its results widely available to the scientific community by implementing findability, accessibility, interoperability and reusability \u2013 i.e. following the FAIR guiding principles. Thus, NUKLEUS might serve as role model for FAIR and fast implementation of clinical epidemiological studies within the setting of University Medical Centers and beyond.<\/jats:p>","DOI":"10.3233\/shti230071","type":"book-chapter","created":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T04:42:52Z","timestamp":1684471372000},"source":"Crossref","is-referenced-by-count":1,"title":["The Importance of Being FAIR and FAST \u2013 The Clinical Epidemiology and Study Platform of the German Network University Medicine (NUKLEUS)"],"prefix":"10.3233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7238-5339","authenticated-orcid":false,"given":"Dagmar","family":"Krefting","sequence":"first","affiliation":[{"name":"Dpt. of Medical Informatics, University Medical Center G\u00f6ttingen, German Center for Cardiovascular Research (DZHK) partner site G\u00f6ttingen, Germany"},{"name":"Campus Institute Data Science (CIDAS), Georg-August-University G\u00f6ttingen, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0483-892X","authenticated-orcid":false,"given":"Gabi","family":"Anton","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology, Helmholtz Zentrum M\u00fcnchen, German Research Center for Environmental Health, Neuherberg, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4811-1028","authenticated-orcid":false,"given":"Irina","family":"Chaplinskaya-Sobol","sequence":"additional","affiliation":[{"name":"Dpt. of Medical Informatics, University Medical Center G\u00f6ttingen, German Center for Cardiovascular Research (DZHK) partner site G\u00f6ttingen, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9133-8685","authenticated-orcid":false,"given":"Sabine","family":"Hanss","sequence":"additional","affiliation":[{"name":"Dpt. of Medical Informatics, University Medical Center G\u00f6ttingen, German Center for Cardiovascular Research (DZHK) partner site G\u00f6ttingen, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6359-8797","authenticated-orcid":false,"given":"Wolfgang","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Institute for Community Medicine, University Medicine Greifswald, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8886-4596","authenticated-orcid":false,"given":"Sina M.","family":"Hopff","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Cologne, Department I of Internal Medicine, University Hospital Cologne, Germany"},{"name":"Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Cologne, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4825-8724","authenticated-orcid":false,"given":"Monika","family":"Kraus","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology, Helmholtz Zentrum M\u00fcnchen, German Research Center for Environmental Health, Neuherberg, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2224-9208","authenticated-orcid":false,"given":"Roberto","family":"Lorbeer","sequence":"additional","affiliation":[{"name":"Medical Heart Center and Institute of Computer-assisted Cardiovascular Medicine, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7215-9174","authenticated-orcid":false,"given":"Bettina","family":"Lorenz-Depiereux","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology, Helmholtz Zentrum M\u00fcnchen, German Research Center for Environmental Health, Neuherberg, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4284-5389","authenticated-orcid":false,"given":"Thomas","family":"Illig","sequence":"additional","affiliation":[{"name":"Hannover Unified Biobank, Hannover Medical School, Hannover, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8873-7231","authenticated-orcid":false,"given":"Christian","family":"Sch\u00e4fer","sequence":"additional","affiliation":[{"name":"Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9399-1653","authenticated-orcid":false,"given":"Jens","family":"Schaller","sequence":"additional","affiliation":[{"name":"Medical Heart Center and Institute of Computer-assisted Cardiovascular Medicine, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4283-4543","authenticated-orcid":false,"given":"Dana","family":"Stahl","sequence":"additional","affiliation":[{"name":"Independent Trusted Third Party of the University Medicine Greifswald, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6379-6534","authenticated-orcid":false,"given":"Heike","family":"Valentin","sequence":"additional","affiliation":[{"name":"Independent Trusted Third Party of the University Medicine Greifswald, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2681-3515","authenticated-orcid":false,"given":"Peter","family":"Heuschmann","sequence":"additional","affiliation":[{"name":"Institute of Clinical Epidemiology and Biometry, University of W\u00fcrzburg; Clinical Trial Center, University Hospital W\u00fcrzburg, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5446-7170","authenticated-orcid":false,"given":"Janne","family":"Vehreschild","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Cologne, Department I of Internal Medicine, University Hospital Cologne, Germany"},{"name":"German Centre for Infection Research (DZIF), partner site Bonn-Cologne, Cologne, Department II for Internal Medicine, Hematology\/Oncology, University Hospital Frankfurt, Frankfurt am Main, Germany"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","Caring is Sharing \u2013 Exploiting the Value in Data for Health and Innovation"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI230071","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T10:55:57Z","timestamp":1685530557000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI230071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,18]]},"ISBN":["9781643683881","9781643683898"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti230071","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"value":"0926-9630","type":"print"},{"value":"1879-8365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,18]]}}}