{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T09:12:26Z","timestamp":1685610746517},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"value":"9781643683881","type":"print"},{"value":"9781643683898","type":"electronic"}],"license":[{"start":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T00:00:00Z","timestamp":1684368000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,18]]},"abstract":"<jats:p>Feature importance is often used to explain clinical prediction models. In this work, we examine three challenges using experiments with electronic health record data: computational feasibility, choosing between methods, and interpretation of the resulting explanation. This work aims to create awareness of the disagreement between feature importance methods and underscores the need for guidance to practitioners how to deal with these discrepancies.<\/jats:p>","DOI":"10.3233\/shti230346","type":"book-chapter","created":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T08:50:03Z","timestamp":1684486203000},"source":"Crossref","is-referenced-by-count":0,"title":["Challenges of Estimating Global Feature Importance in Real-World Health Care Data"],"prefix":"10.3233","author":[{"given":"Aniek F.","family":"Markus","sequence":"first","affiliation":[{"name":"Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Egill A.","family":"Fridgeirsson","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan A.","family":"Kors","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katia M.C.","family":"Verhamme","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter R.","family":"Rijnbeek","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","Caring is Sharing \u2013 Exploiting the Value in Data for Health and Innovation"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI230346","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T15:04:17Z","timestamp":1685545457000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI230346"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,18]]},"ISBN":["9781643683881","9781643683898"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti230346","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"value":"0926-9630","type":"print"},{"value":"1879-8365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,18]]}}}