{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T09:49:34Z","timestamp":1747216174067,"version":"3.40.5"},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"type":"print","value":"9781643684567"},{"type":"electronic","value":"9781643684574"}],"license":[{"start":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T00:00:00Z","timestamp":1706140800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,25]]},"abstract":"<jats:p>Radiation therapy interruptions drive cancer treatment failures; they represent an untapped opportunity for improving outcomes and narrowing treatment disparities. This research reports on the early development of the X-CART platform, which uses explainable AI to model cancer treatment outcome metrics based on high-dimensional associations with our local social determinants of health dataset to identify and explain causal pathways linking social disadvantage with increased radiation therapy interruptions.<\/jats:p>","DOI":"10.3233\/shti231264","type":"book-chapter","created":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T10:31:23Z","timestamp":1706178683000},"source":"Crossref","is-referenced-by-count":1,"title":["Towards an Explainable AI Platform to Study Interruptions in Cancer Radiation Therapy"],"prefix":"10.3233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2047-4759","authenticated-orcid":false,"given":"Arash","family":"Shaban-Nejad","sequence":"first","affiliation":[{"name":"University of Tennessee Health Science Center \u2013 Oak-Ridge National Lab (UTHSC-ORNL) Center for Biomedical Informatics, Department of Pediatrics, College of Medicine, Memphis, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nariman","family":"Ammar","sequence":"additional","affiliation":[{"name":"School of Information Technology, College of Applied Science and Technology, Illinois State University, Normal, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fekede","family":"Kumsa","sequence":"additional","affiliation":[{"name":"University of Tennessee Health Science Center \u2013 Oak-Ridge National Lab (UTHSC-ORNL) Center for Biomedical Informatics, Department of Pediatrics, College of Medicine, Memphis, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soheil","family":"Hashtarkhani","sequence":"additional","affiliation":[{"name":"University of Tennessee Health Science Center \u2013 Oak-Ridge National Lab (UTHSC-ORNL) Center for Biomedical Informatics, Department of Pediatrics, College of Medicine, Memphis, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brianna","family":"White","sequence":"additional","affiliation":[{"name":"University of Tennessee Health Science Center \u2013 Oak-Ridge National Lab (UTHSC-ORNL) Center for Biomedical Informatics, Department of Pediatrics, College of Medicine, Memphis, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lokesh K.","family":"Chinthala","sequence":"additional","affiliation":[{"name":"University of Tennessee Health Science Center \u2013 Oak-Ridge National Lab (UTHSC-ORNL) Center for Biomedical Informatics, Department of Pediatrics, College of Medicine, Memphis, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chase A.","family":"Owens","sequence":"additional","affiliation":[{"name":"University of Tennessee Health Science Center, Memphis, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil","family":"Hayes","sequence":"additional","affiliation":[{"name":"Division of Med Hematology, Department of Medicine, University of Tennessee Health Science Center, College of Medicine, Memphis, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David L.","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Departments of Radiation Oncology & Preventive Medicine University of Tennessee Health Science Center, College of Medicine, Memphis, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","MEDINFO 2023 \u2014 The Future Is Accessible"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI231264","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T10:31:25Z","timestamp":1706178685000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI231264"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,25]]},"ISBN":["9781643684567","9781643684574"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti231264","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"type":"print","value":"0926-9630"},{"type":"electronic","value":"1879-8365"}],"subject":[],"published":{"date-parts":[[2024,1,25]]}}}