{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T17:42:41Z","timestamp":1774374161412,"version":"3.50.1"},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"value":"9781643685366","type":"electronic"}],"license":[{"start":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T00:00:00Z","timestamp":1724976000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,30]]},"abstract":"<jats:p>Individual health data is crucial for scientific advancements, particularly in developing Artificial Intelligence (AI); however, sharing real patient information is often restricted due to privacy concerns. A promising solution to this challenge is synthetic data generation. This technique creates entirely new datasets that mimic the statistical properties of real data, while preserving confidential patient information. In this paper, we present the workflow and different services developed in the context of Germany\u2019s National Data Infrastructure project NFDI4Health. First, two state-of-the-art AI tools (namely, VAMBN and MultiNODEs) for generating synthetic health data are outlined. Further, we introduce SYNDAT (a public web-based tool) which allows users to visualize and assess the quality and risk of synthetic data provided by desired generative models. Additionally, the utility of the proposed methods and the web-based tool is showcased using data from Alzheimer\u2019s Disease Neuroimaging Initiative (ADNI) and the Center for Cancer Registry Data of the Robert Koch Institute (RKI).<\/jats:p>","DOI":"10.3233\/shti240834","type":"book-chapter","created":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T08:58:37Z","timestamp":1725526717000},"source":"Crossref","is-referenced-by-count":4,"title":["NFDI4Health Workflow and Service for Synthetic Data Generation, Assessment and Risk Management"],"prefix":"10.3233","author":[{"given":"Sobhan","family":"Moazemi","sequence":"first","affiliation":[{"name":"Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing SCAI, Sankt Augustin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing SCAI, Sankt Augustin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hwei Geok","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing SCAI, Sankt Augustin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"K\u00fchnel","sequence":"additional","affiliation":[{"name":"Knowledge Management, ZB MED \u2013 Information Centre for Life Sciences, Cologne, Germany"},{"name":"Graduate School DILS, Bielefeld Institute for Bioinformatics Infrastructure (BIBI), Faculty of Technology, Bielefeld University, Bielefeld, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Schneider","sequence":"additional","affiliation":[{"name":"Knowledge Management, ZB MED \u2013 Information Centre for Life Sciences, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anatol-Fiete","family":"N\u00e4her","sequence":"additional","affiliation":[{"name":"Digital Global Public Health, Hasso Plattner Institute for Digital Engineering, University of Potsdam, Potsdam, Germany"},{"name":"Institute of Medical Informatics, Charit\u00e9\u2013Universit\u00e4tsmedizin"},{"name":"Method Development, Research Infrastructure, and Information Technology, Robert Koch Institute, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliane","family":"Fluck","sequence":"additional","affiliation":[{"name":"Knowledge Management, ZB MED \u2013 Information Centre for Life Sciences, Cologne, Germany"},{"name":"The Agricultural Faculty, University of Bonn, Bonn, Germany"},{"name":"Institute for Geodesy and Geoinformation, University of Bonn, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holger","family":"Fr\u00f6hlich","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing SCAI, Sankt Augustin, Germany"},{"name":"Bonn-Aachen International Center for Information Technology (B-it), University of Bonn, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","German Medical Data Sciences 2024"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI240834","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T08:58:38Z","timestamp":1725526718000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI240834"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,30]]},"ISBN":["9781643685366"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti240834","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"value":"0926-9630","type":"print"},{"value":"1879-8365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,30]]}}}