{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T12:31:31Z","timestamp":1787056291472,"version":"3.56.0"},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"value":"9781643685960","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:00:00Z","timestamp":1747267200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,15]]},"abstract":"<jats:p>*CORRIGENDUM on final page* The role played by physical activity in slowing down the progression of type-2 diabetes is well recognized. However, except for general clinical guidelines, quantitative real-time estimates of the recommended amount of physical activity, based on the evolving individual conditions, are still missing in the literature. The aim of this work is to provide a control-theoretical formulation of the exercise encoding all the exercise-related features (intensity, duration, period). Specifically, we design a feedback law in terms of recommended physical activity, following a model predictive control approach, based on a widespread compact diabetes progression model, suitably modified to account for the long-term effects of regular exercise. Preliminary simulations show promising results, well aligned with clinical evidence. These findings can be the basis for further validation of the control law on high-dimensional diabetes progression models to ultimately translate the predictions of the controller into meaningful recommendations.<\/jats:p>","DOI":"10.3233\/shti250267","type":"book-chapter","created":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T04:52:13Z","timestamp":1747371133000},"source":"Crossref","is-referenced-by-count":1,"title":["A Model-Based Approach for Glucose Control via Physical Activity"],"prefix":"10.3233","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5198-0293","authenticated-orcid":false,"given":"Pierluigi Francesco","family":"de Paola","sequence":"first","affiliation":[{"name":"Polytechnic of Bari, Bari, Italy"},{"name":"Consiglio Nazionale delle Ricerche \u2013 Istituto di Elettronica e di Ingegneria dell\u2019Informazione e delle Telecomunicazioni (CNR-IEIIT), Turin, Milan, Italy"},{"name":"Consiglio Nazionale delle Ricerche \u2013 Istituto di Analisi dei Sistemi ed Informatica (CNR-IASI), Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6678-048X","authenticated-orcid":false,"given":"Alessandro","family":"Borri","sequence":"additional","affiliation":[{"name":"Consiglio Nazionale delle Ricerche \u2013 Istituto di Analisi dei Sistemi ed Informatica (CNR-IASI), Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1341-2560","authenticated-orcid":false,"given":"Alessia","family":"Paglialonga","sequence":"additional","affiliation":[{"name":"Consiglio Nazionale delle Ricerche \u2013 Istituto di Elettronica e di Ingegneria dell\u2019Informazione e delle Telecomunicazioni (CNR-IEIIT), Turin, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9371-2802","authenticated-orcid":false,"given":"Pasquale","family":"Palumbo","sequence":"additional","affiliation":[{"name":"Dept. Of Biotechnologies and Biosciences, University of Milano-Bicocca, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2258-8971","authenticated-orcid":false,"given":"Fabrizio","family":"Dabbene","sequence":"additional","affiliation":[{"name":"Consiglio Nazionale delle Ricerche \u2013 Istituto di Elettronica e di Ingegneria dell\u2019Informazione e delle Telecomunicazioni (CNR-IEIIT), Turin, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","Intelligent Health Systems \u2013 From Technology to Data and Knowledge"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI250267","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T12:13:46Z","timestamp":1787055226000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI250267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,15]]},"ISBN":["9781643685960"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti250267","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"value":"0926-9630","type":"print"},{"value":"1879-8365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,15]]}}}