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A set of European experts defined four research areas and associated challenges: i) to characterize the value of Common Data Models, vocabularies and standardized data elements for creating the foundation for the standardization of Intensive Care Unit (ICU) data sets, ii) to derive the Common Data Model ensuring seamless data interoperability supporting the querying and access to high-quality, multi-modal data located on federated nodes according to the FAIR principles, iii) to define and support the data standardization process enabling efficient secondary use of ICU data set during the execution of key decision support use cases through the Intensive Medicine Data Space in Europe and beyond, and iv) to define requirements for anonymization and pseudonymization for the good balance between data protection and innovation.<\/jats:p>","DOI":"10.3233\/shti250393","type":"book-chapter","created":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T08:55:39Z","timestamp":1747385739000},"source":"Crossref","is-referenced-by-count":1,"title":["Towards the Common Data Model for an Intensive Medicine Data Space in Europe"],"prefix":"10.3233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2609-575X","authenticated-orcid":false,"given":"Carlos Luis","family":"Parra-Calder\u00f3n","sequence":"first","affiliation":[{"name":"Computational Health Informatics Group, Institute of Biomedicine of Seville, IBIS\/ Virgen del Roc\u00edo University Hospital\/CSIC\/University of Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8647-9515","authenticated-orcid":false,"given":"Celia","family":"Alvarez-Romero","sequence":"additional","affiliation":[{"name":"Computational Health Informatics Group, Institute of Biomedicine of Seville, IBIS\/ Virgen del 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