{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,17]],"date-time":"2025-05-17T04:04:34Z","timestamp":1747454674211,"version":"3.40.5"},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"value":"9781643685960","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:00:00Z","timestamp":1747267200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,15]]},"abstract":"<jats:p>Early-stage cancer diagnosis improves treatment options and prognosis but is influenced by demographic and socio-economic inequalities. This study examined how sociodemographic factors relate to the stage at diagnosis among men aged \u226556 diagnosed with prostate cancer from 2010-2016, using data from the National Cancer Registration and Analysis Service (NCRAS). The differences between groups in the proportions of localised, locally advanced, or advanced cancer stages were analysed using chi-square tests and multinomial logistic regression to assess associations with age, ethnicity, deprivation, and region adjusting for comorbidity and year of diagnosis. Among 13,693 men, 45% had localised, 34% locally advanced, and 21% advanced-stage prostate cancer. Stage at diagnosis varied significantly by age (p&lt;0.001), deprivation (p=0.038), ethnicity (p=0.044), and region (p&lt;0.001). Men who were over 80 years old, compared to men who were 65 and below had an adjusted odds ratio (aOR) of 13.2 (95% confidence interval was 11.0 to 16.0, p&lt;0.001), those from most deprived areas (aOR=1.2 (1.0 to 1.5), p=0.014), and whose registered primary care practice was in the East Midlands (aOR=1.6 (1.2 to 2.2), p&lt;0.001) were more likely to be diagnosed at advanced stages. In contrast, Asian men had lower odds of advanced-stage diagnoses (aOR=0.6 (0.4 to 0.9), p=0.03) compared to White men. These findings underscore the influence of age, deprivation, ethnicity, and region on prostate cancer stage at diagnosis, highlighting the need for more in-depth research and targeted interventions for at-risk groups.<\/jats:p>","DOI":"10.3233\/shti250565","type":"book-chapter","created":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T09:00:38Z","timestamp":1747386038000},"source":"Crossref","is-referenced-by-count":0,"title":["Sociodemographic Disparities in the Stage of Prostate Cancer Diagnosis in England: A Population-Based Analysis Using Linked Electronic Health Records Data"],"prefix":"10.3233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1689-3881","authenticated-orcid":false,"given":"Gayasha","family":"Somathilake","sequence":"first","affiliation":[{"name":"School of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnieszka","family":"Lemanska","sequence":"additional","affiliation":[{"name":"School of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, UK"},{"name":"Data Science, National Physical Laboratory, Teddington, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo","family":"Armes","sequence":"additional","affiliation":[{"name":"School of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sotiris","family":"Moschoyiannis","sequence":"additional","affiliation":[{"name":"Computer Science Research Centre, Faculty of Engineering and Physical Sciences, University of Surrey, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Ford","sequence":"additional","affiliation":[{"name":"Department of Primary Care and Public Health, Brighton and Sussex Medical School, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","Intelligent Health Systems \u2013 From Technology to Data and Knowledge"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI250565","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T09:00:39Z","timestamp":1747386039000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI250565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,15]]},"ISBN":["9781643685960"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti250565","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"value":"0926-9630","type":"print"},{"value":"1879-8365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,15]]}}}