{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T08:44:04Z","timestamp":1771058644164,"version":"3.50.1"},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"value":"9781643686080","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T00:00:00Z","timestamp":1754524800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,7]]},"abstract":"<jats:p>Epilepsy requires accurate diagnosis through systematic classification of patients for effective treatment, targeted therapeutic interventions, and structured research for enhanced patient care. Over the past few decades, the four-dimensional epilepsy classification (4D-EC) that includes seizure classification based exclusively on ictal symptomatology has been widely adopted and tested. Recent studies have defined a mapping between the 4D-EC and the International League Against Epilepsy (ILAE) classification for seizures and epilepsies (ILAE-EC), which is likely to further advance the adoption of the 4D-EC. However, the absence of a dedicated informatics platform to implement the 4D-EC has limited its widespread clinical implementation and educational use. Therefore, we developed the first 4D-EC informatics tool to facilitate patient data reporting, analysis, and training of new investigators. Our web-based tool incorporates standardized terminology, dynamic user-driven workflows, and automated summary generation, enhancing clinical decision support and training of epileptologists. Our work presents the development of this application, which is accessible at https:\/\/bmhinformatics.case.edu\/epilepsy4d\/.<\/jats:p>","DOI":"10.3233\/shti250809","type":"book-chapter","created":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T11:31:48Z","timestamp":1754566308000},"source":"Crossref","is-referenced-by-count":1,"title":["Standardized Epilepsy Data Collection and Analysis Leveraging the Four Dimensional Epilepsy Classification (4D-EC) Framework"],"prefix":"10.3233","author":[{"given":"Katrina","family":"Prantzalos","sequence":"first","affiliation":[{"name":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA"}]},{"given":"Pedram","family":"Golnari","sequence":"additional","affiliation":[{"name":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA"}]},{"given":"Dipak","family":"Upadhyaya","sequence":"additional","affiliation":[{"name":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA"}]},{"given":"Suraj","family":"Thyagaraj","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA"}]},{"given":"Guadalupe","family":"Fernandez-Bacavaca","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA"}]},{"given":"Hans","family":"Luders","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA"}]},{"given":"Satya S.","family":"Sahoo","sequence":"additional","affiliation":[{"name":"Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","MEDINFO 2025 \u2014 Healthcare Smart \u00d7 Medicine Deep"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI250809","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T11:31:48Z","timestamp":1754566308000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI250809"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,7]]},"ISBN":["9781643686080"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti250809","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"value":"0926-9630","type":"print"},{"value":"1879-8365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,7]]}}}