{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T02:28:55Z","timestamp":1769826535119,"version":"3.49.0"},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"value":"9781643686080","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T00:00:00Z","timestamp":1754524800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,7]]},"abstract":"<jats:p>De-identifying private information in medical records is crucial to prevent confidentiality breaches. Rule-based and learning-based methods struggle with generalizability and require large annotated datasets, while LLMs offer better language comprehension but face privacy risks and high computational costs. We propose LPPA, an LLM-empowered Privacy-protected PHI Annotation framework, which uses few-shot learning with pre-trained LLMs to generate synthetic clinical notes, reducing the need for extensive datasets. By fine-tuning LLMs locally with synthetic notes, LPPA ensures strong privacy protection and high PHI annotation accuracy. Experiments confirm its effectiveness, efficiency, and scalability.<\/jats:p>","DOI":"10.3233\/shti250965","type":"book-chapter","created":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T11:36:39Z","timestamp":1754566599000},"source":"Crossref","is-referenced-by-count":1,"title":["Large Language Model Empowered Privacy-Protected Framework for PHI Annotation in Clinical Notes"],"prefix":"10.3233","author":[{"given":"Guanchen","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Computer Science, Emory University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linzhi","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Computer Science, University of Chicago"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Computer Science, Emory University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Xiang","sequence":"additional","affiliation":[{"name":"School of Computing, University of Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaying","family":"Lu","sequence":"additional","affiliation":[{"name":"Nell Hodgson Woodruff School of Nursing, Emory University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darren","family":"Liu","sequence":"additional","affiliation":[{"name":"Nell Hodgson Woodruff School of Nursing, Emory University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delgersuren","family":"Bold","sequence":"additional","affiliation":[{"name":"Nell Hodgson Woodruff School of Nursing, Emory University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Computer Science, University of Chicago"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Hu","sequence":"additional","affiliation":[{"name":"Nell Hodgson Woodruff School of Nursing, Emory University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Computer Science, Emory University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","MEDINFO 2025 \u2014 Healthcare Smart \u00d7 Medicine Deep"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI250965","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T11:36:39Z","timestamp":1754566599000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI250965"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,7]]},"ISBN":["9781643686080"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti250965","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"value":"0926-9630","type":"print"},{"value":"1879-8365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,7]]}}}