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The program addressed the limitations of traditional source-image-based analysis, including manufacturer dependency, high storage costs, and limited accessibility. High intraclass correlation coefficient (ICC) values for cerebral blood volume and time to peak confirmed the feasibility of this approach, whereas lower ICC values for mean transit time suggested discrepancies between reconstructed RGB images and conventional dynamic susceptibility contrast\u2013based data. Designed with a user-friendly graphical user interface and executable distribution, the program enhances clinical applicability. Future studies should focus on improving the algorithms and validating the approach with multicenter datasets.<\/jats:p>","DOI":"10.3233\/shti250969","type":"book-chapter","created":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T11:36:42Z","timestamp":1754566602000},"source":"Crossref","is-referenced-by-count":0,"title":["A New Approach to Perfusion-Weighted Image Analysis: Measurement via Red\u2013Green\u2013Blue Information Inversion"],"prefix":"10.3233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8197-2781","authenticated-orcid":false,"given":"Taeyeon","family":"Kim","sequence":"first","affiliation":[{"name":"Medical Research Institute, Pohang Stroke and Spine Hospital, Pohang, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4069-9843","authenticated-orcid":false,"given":"Youngsoo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Pohang Stroke and Spine Hospital, Pohang, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1826-5839","authenticated-orcid":false,"given":"Youjin","family":"Lee","sequence":"additional","affiliation":[{"name":"Medical Research Institute, Pohang Stroke and Spine Hospital, Pohang, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4439-6097","authenticated-orcid":false,"given":"Injung","family":"Kim","sequence":"additional","affiliation":[{"name":"School of Computer Science and Electrical Engineering, Handong Global University, Pohang, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2841-8003","authenticated-orcid":false,"given":"Seungeon","family":"Song","sequence":"additional","affiliation":[{"name":"School of Computer Science and Electrical Engineering, Handong Global University, Pohang, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5037-3856","authenticated-orcid":false,"given":"Seokwon","family":"Kim","sequence":"additional","affiliation":[{"name":"School of Computer Science and Electrical Engineering, Handong Global University, Pohang, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6255-2882","authenticated-orcid":false,"given":"Jinyoung","family":"Choi","sequence":"additional","affiliation":[{"name":"School of Computer Science and Electrical Engineering, Handong Global University, Pohang, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1288-470X","authenticated-orcid":false,"given":"Dougho","family":"Park","sequence":"additional","affiliation":[{"name":"Medical Research Institute, Pohang Stroke and Spine Hospital, Pohang, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","MEDINFO 2025 \u2014 Healthcare Smart \u00d7 Medicine Deep"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI250969","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T11:36:42Z","timestamp":1754566602000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI250969"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,7]]},"ISBN":["9781643686080"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti250969","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"type":"print","value":"0926-9630"},{"type":"electronic","value":"1879-8365"}],"subject":[],"published":{"date-parts":[[2025,8,7]]}}}