{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T23:05:06Z","timestamp":1779404706163,"version":"3.53.1"},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"value":"9781643686615","type":"electronic"}],"license":[{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,21]]},"abstract":"<jats:p>Protecting privacy is essential when handling personal medical records. Even in pseudonymized health data, identifying individual patients remains a persistent risk in large medical datasets. The German Research Data Portal for Health (FDPG) provides access to extensive patient-derived routine data, including diagnoses, procedures, laboratory results, oncological findings, images, and genomic information. These data are stored locally at participating sites and harmonized through a common HL7 FHIR-based model. The portal\u2019s feasibility query function allows users to define complex cohorts using diverse search criteria and retrieves real-time patient counts from all German university hospitals and beyond. Despite the high aggregation level, re-identification risks persist due to potential prior knowledge or repeated (\u201ctracker\u201d) queries. The FDPG therefore aims to minimize re-identification risk while preserving sufficient data utility for meaningful data discovery. Here, we present the data protection approach implemented in the distributed FDPG infrastructure and share insights from its first two years of operation, offering a blueprint for the upcoming European Health Data Space (EHDS).<\/jats:p>","DOI":"10.3233\/shti260444","type":"book-chapter","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T22:05:09Z","timestamp":1779401109000},"source":"Crossref","is-referenced-by-count":0,"title":["Accurate Yet Privacy-Preserving Determination of Case Numbers Across German University Hospital Health Data"],"prefix":"10.3233","author":[{"given":"Philip","family":"Overton","sequence":"first","affiliation":[{"name":"TMF - Technology, Methods, and Infrastructure for Networked Medical Research, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Kiel","sequence":"additional","affiliation":[{"name":"Leipzig Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian C.","family":"Semler","sequence":"additional","affiliation":[{"name":"TMF - Technology, Methods, and Infrastructure for Networked Medical Research, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Prasser","sequence":"additional","affiliation":[{"name":"Medical Informatics Group, Berlin Institute of Health at Charit\u00e9 - Universit\u00e4tsmedizin Berlin, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Kussel","sequence":"additional","affiliation":[{"name":"Federated Information Systems, German Cancer Research Center (DKFZ), Heidelberg, Germany"},{"name":"Complex Medical Informatics, Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany"},{"name":"German Cancer Consortium (DKTK), Core Center Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Ganslandt","sequence":"additional","affiliation":[{"name":"Chair of Medical Informatics Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Gruendner","sequence":"additional","affiliation":[{"name":"Chair of Medical Informatics Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","Opening the Personal Gate between Technology and Health Care"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI260444","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T22:05:09Z","timestamp":1779401109000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI260444"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,21]]},"ISBN":["9781643686615"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti260444","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"value":"0926-9630","type":"print"},{"value":"1879-8365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,21]]}}}