{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T15:19:43Z","timestamp":1783610383896,"version":"3.55.0"},"reference-count":0,"publisher":"IOS Press","isbn-type":[{"value":"9781643686615","type":"electronic"}],"license":[{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,21]]},"abstract":"<jats:p>Precision oncology (PO) has revolutionized cancer treatment by aligning therapy with a tumor\u2019s molecular profile. The integration of next-generation sequencing (NGS) has allowed for actionable genomic alterations to inform treatment decisions. However, challenges remain in streamlining NGS results and integrating them into clinical workflows, particularly in the context of Molecular Tumor Boards (MTBs). This study presents an integrated platform designed to support MTB decision-making by consolidating clinical and molecular data from heterogeneous sources using an ETL (Extract, Transform, Load) process. The platform automates data loading, significantly reducing clinicians\u2019 time on manual data entry and provides a data integration view of the patient status helping decision making. A total of 69 variables, encompassing clinical, molecular, and MTB recommendations, were integrated into the platform. From February 2024 to September 2025, the platform collected data from 1.119 patients and 1.221 NGS results, with 30% of cases receiving therapeutic recommendations. This approach enhances clinical care, promotes data interoperability, and supports PO in a real-world MTB workflow.<\/jats:p>","DOI":"10.3233\/shti260507","type":"book-chapter","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T22:07:00Z","timestamp":1779401220000},"source":"Crossref","is-referenced-by-count":0,"title":["Modelling and Implementation of a Precision-Oncology Data-Integration Platform for Real-Word Molecular Tumor Borad Decision-Making"],"prefix":"10.3233","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0749-8409","authenticated-orcid":false,"given":"Julia","family":"Hernandez-Sanchez","sequence":"first","affiliation":[{"name":"Digital Transformation and Biomedical Engineering Group, Research Institute Hospital 12 de Octubre, Madrid, Spain"},{"name":"ETSI Telecomunicaci\u00f3n, Universidad Polit\u00e9cnica de Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1ngel","family":"Mart\u00ednez-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hospital Universitario 12 de Octubre, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Cruz-Ballesteros","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hospital Universitario 12 de Octubre, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Baena-Espinar","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hospital Universitario 12 de Octubre, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Elena","family":"Hernando","sequence":"additional","affiliation":[{"name":"ETSI Telecomunicaci\u00f3n, Universidad Polit\u00e9cnica de Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana","family":"Hern\u00e1ndez-Prieto","sequence":"additional","affiliation":[{"name":"Department of Pathological Anatomy, Hospital Universitario 12 de Octubre, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"L\u00f3pez-R\u00edos","sequence":"additional","affiliation":[{"name":"Department of Pathological Anatomy, Hospital Universitario 12 de Octubre, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noelia","family":"Garc\u00eda Barrio","sequence":"additional","affiliation":[{"name":"Digital Transformation and Biomedical Engineering Group, Research Institute Hospital 12 de Octubre, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Ponce-Aix","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hospital Universitario 12 de Octubre, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Paz-Ares-Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hospital Universitario 12 de Octubre, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Luis","family":"Cruz-Berm\u00fadez","sequence":"additional","affiliation":[{"name":"Digital Transformation and Biomedical Engineering Group, Research Institute Hospital 12 de Octubre, Madrid, Spain"},{"name":"ETSI Telecomunicaci\u00f3n, Universidad Polit\u00e9cnica de Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7437","container-title":["Studies in Health Technology and Informatics","Opening the Personal Gate between Technology and Health Care"],"original-title":[],"link":[{"URL":"https:\/\/ebooks.iospress.nl\/pdf\/doi\/10.3233\/SHTI260507","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T15:03:23Z","timestamp":1783609403000},"score":1,"resource":{"primary":{"URL":"https:\/\/ebooks.iospress.nl\/doi\/10.3233\/SHTI260507"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,21]]},"ISBN":["9781643686615"],"references-count":0,"URL":"https:\/\/doi.org\/10.3233\/shti260507","relation":{},"ISSN":["0926-9630","1879-8365"],"issn-type":[{"value":"0926-9630","type":"print"},{"value":"1879-8365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,21]]}}}