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We present a usability evaluation approach and study of a semantic framework (i.e. Knowledge Graph, Methodology and User Interface) to enable Health Data Researchers (HDR) to link particular health events with environmental data for rare disease research. The usability study includes 17 HDRs with expertise in health data related to Anti-Neutrophil Cytoplasmic Antibody (ANCA)-associated vasculitis (AAV) in Ireland and Kawasaki Disease in Japan, and with no previous practical experience in using Semantic Web (SW) technologies. The evaluation results are promising in that they indicate that the framework is useful in allowing researchers themselves to link health and environmental data whilst hiding the complexities of SW technologies. As a result of this work, we also discuss the limitations of the approach together with the applicability to other domains. Beyond the direct impact on environmental health studies, the description of the evaluation approach can guide researchers in making SW technologies more accessible to domain experts through usability studies.<\/jats:p>","DOI":"10.3233\/sw-223212","type":"journal-article","created":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T11:46:39Z","timestamp":1667562399000},"page":"787-810","source":"Crossref","is-referenced-by-count":4,"title":["Evaluating the usability of a semantic environmental health data framework: Approach and study"],"prefix":"10.1177","volume":"14","author":[{"given":"Albert","family":"Navarro-Gallinad","sequence":"first","affiliation":[{"name":"ADAPT Centre for Digital Content, School of Computer Science and Statistics, Trinity College Dublin, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrizio","family":"Orlandi","sequence":"additional","affiliation":[{"name":"ADAPT Centre for Digital Content, School of Computer Science and 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