{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T16:10:34Z","timestamp":1786378234082,"version":"build-2736575974"},"reference-count":54,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T00:00:00Z","timestamp":1615420800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer's Disease Reports"],"published-print":{"date-parts":[[2021,3,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The presence of recurrent, complex visual hallucinations (VH) is among the core clinical features of dementia with Lewy bodies (DLB). It has been proposed that VH arise from a disrupted organization of functional brain networks. However, studies are still limited, especially investigating the resting-state functional brain features underpinning VH in patients with dementia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The aim of the present pilot study was to investigate whether there were any alterations in functional connectivity associated with VH in DLB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Seed-based analyses and independent component analysis (ICA) of resting-state fMRI scans were carried out to explore differences in functional connectivity between DLB patients with and without VH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Seed-based analyses reported decreased connectivity of the lateral geniculate nucleus, the superior parietal lobule and the putamen with the medial frontal gyrus in DLB patients with VH. Visual areas showed a pattern of both decreased and increased functional connectivity. ICA revealed between-group differences in the default mode network (DMN).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Functional connectivity analyses suggest dysfunctional top-down and bottom-up processes and DMN-related alterations in DLB patients with VH. This impairment might foster the generation of false visual images that are misinterpreted, ultimately resulting in VH.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/adr-200288","type":"journal-article","created":{"date-parts":[[2021,4,16]],"date-time":"2021-04-16T12:28:33Z","timestamp":1618576113000},"page":"311-320","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Functional Brain Connectivity Patterns Associated with Visual Hallucinations in Dementia with Lewy Bodies"],"prefix":"10.1177","volume":"5","author":[{"given":"Stefania","family":"Pezzoli","sequence":"first","affiliation":[{"name":"Department of Neuroscience, Medical School, University of Sheffield, Sheffield, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"De Marco","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Medical School, University of Sheffield, Sheffield, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Zorzi","sequence":"additional","affiliation":[{"name":"Department of Neuroscience and Padua Neuroscience Center, University of Padua, Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annachiara","family":"Cagnin","sequence":"additional","affiliation":[{"name":"Department of Neuroscience and Padua Neuroscience Center, University of Padua, Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalena","family":"Venneri","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Medical School, University of Sheffield, Sheffield, UK"},{"name":"Department of Life Sciences, Brunel University London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,4,16]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000004058"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1017\/S0140525X05000130"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23896"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2010.01.003"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20965"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1159\/000100850"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.57.4.489"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp166"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.2019.1656515"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2013.04.026"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.22321"},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci7070084"},{"key":"ref013","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26285"},{"key":"ref014","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26004"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/703924"},{"key":"ref016","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2014.01.004"},{"key":"ref017","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.22577"},{"key":"ref018","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27557"},{"key":"ref019","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-014-0907-5"},{"key":"ref020","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000187889.17253.b1"},{"key":"ref021","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2011.03.005"},{"key":"ref022","unstructured":"FahnS, EltonRL (1987) Members of the Unified Parkinson\u2019s Disease Rating Scale Development Committee: Unified Parkinson\u2019s disease rating scale. 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