{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:14:27Z","timestamp":1777392867722,"version":"3.51.4"},"reference-count":59,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T00:00:00Z","timestamp":1704758400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer's Disease Reports"],"published-print":{"date-parts":[[2024,1,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Excessive daytime sleepiness (EDS) and caudate nucleus volume alterations have been linked to Alzheimer\u2019s disease (AD), but their relationship remains unclear under the context of subjective cognitive decline (SCD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This study aimed to investigate the relationship between EDS and caudate nucleus volume in patients with SCD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The volume of entire brain was measured in 170 patients with SCD, including 37 patients with EDS and 133 non-EDS, from the Sino Longitudinal Study on Cognitive Decline (SILCODE). Participants underwent a comprehensive assessment battery, including neuropsychological and clinical evaluations, blood tests, genetic analysis for APOE \u025b4, and structural MRI scans analyzed using the fully automated segmentation tool, volBrain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Patients with EDS had significantly increased volume in the total and left caudate nucleus compared to non-EDS. The most significant cognitive behavioral factor associated with caudate nucleus volume in the EDS was the Auditory Verbal Learning Test-recognition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>These findings suggest that EDS may be associated with alterations in caudate nucleus volume, particularly in the left hemisphere, in the context of SCD. Further research is necessary to understand the underlying mechanisms of this relationship and its implications for clinical management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3233\/adr-230101","type":"journal-article","created":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T11:40:09Z","timestamp":1718710809000},"page":"935-944","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Relationship Between Excessive Daytime Sleepiness and Caudate Nucleus Volume in Patients with Subjective Cognitive Decline: A Study from the SILCODE Using the Volbrain"],"prefix":"10.1177","volume":"8","author":[{"given":"Ziqian","family":"Feng","sequence":"first","affiliation":[{"name":"MOE Key Lab for Neuroinformation, School of Life Science and Technology, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China"},{"name":"Department of Geriatrics, The Fourth People\u2019s Hospital of Chengdu, Chengdu, China"},{"name":"Zunyi Medical and Pharmaceutical College, Zunyi, Guizhou, China"},{"name":"Zunyi Medical University, Zunyi, Guizhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiayu","family":"Wang","sequence":"additional","affiliation":[{"name":"MOE Key Lab for Neuroinformation, School of Life Science and Technology, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China"},{"name":"Department of Geriatrics, The Fourth People\u2019s Hospital of Chengdu, Chengdu, China"},{"name":"Zunyi Medical University, Zunyi, Guizhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisi","family":"Xu","sequence":"additional","affiliation":[{"name":"MOE Key Lab for Neuroinformation, School of Life Science and Technology, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China"},{"name":"Department of Geriatrics, The Fourth People\u2019s Hospital of Chengdu, Chengdu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiajing","family":"Wu","sequence":"additional","affiliation":[{"name":"MOE Key Lab for Neuroinformation, School of Life Science and Technology, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China"},{"name":"Zunyi Medical University, Zunyi, Guizhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyi","family":"Li","sequence":"additional","affiliation":[{"name":"MOE Key Lab for Neuroinformation, School of Life Science and Technology, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China"},{"name":"Department of Geriatrics, The Fourth People\u2019s Hospital of Chengdu, Chengdu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziqi","family":"Wang","sequence":"additional","affiliation":[{"name":"MOE Key Lab for Neuroinformation, School of Life Science and Technology, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China"},{"name":"Department of Geriatrics, The Fourth People\u2019s Hospital of Chengdu, Chengdu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingjun","family":"Duan","sequence":"additional","affiliation":[{"name":"MOE Key Lab for Neuroinformation, School of Life Science and Technology, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China"},{"name":"Department of Geriatrics, The Fourth People\u2019s Hospital of Chengdu, Chengdu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,6,18]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1159\/000514967"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.2070"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2014.01.001"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001712"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2017.04.008"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2021.04.031"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1016\/j.dadm.2018.12.009"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1111\/cns.12395"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-49914-3"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2019.08.082"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-96453-x"},{"key":"ref012","first-page":"e24473","volume":"14","author":"Matz OC","year":"2022","journal-title":"Cureus"},{"key":"ref013","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abm1971"},{"key":"ref014","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2019.01353"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1093\/ijnp\/pyab091"},{"key":"ref016","doi-asserted-by":"publisher","DOI":"10.1111\/ane.12800"},{"key":"ref017","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2013.03.012"},{"key":"ref018","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2010.05.002"},{"key":"ref019","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-022-00715-9"},{"key":"ref020","doi-asserted-by":"publisher","DOI":"10.3233\/BPL-190087"},{"key":"ref021","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202204717"},{"key":"ref022","doi-asserted-by":"publisher","DOI":"10.1002\/dad2.12212"},{"key":"ref023","doi-asserted-by":"publisher","DOI":"10.1186\/alzrt47"},{"key":"ref024","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-018-9835-y"},{"key":"ref025","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2021.610755"},{"key":"ref026","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2018-028188"},{"key":"ref027","doi-asserted-by":"publisher","DOI":"10.1186\/s13195-019-0505-0"},{"key":"ref028","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-140276"},{"key":"ref029","doi-asserted-by":"publisher","DOI":"10.1186\/s13195-022-00977-x"},{"key":"ref030","unstructured":"Alzheimer\u2019s disease specialist in China\n (2018) Expert consensus on preclinical SCD diagnosis process and specification of Alzheimer\u2019s disease in China."},{"key":"ref031","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-190501"},{"key":"ref032","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2020.08.033"},{"key":"ref033","doi-asserted-by":"publisher","DOI":"10.1016\/j.jegh.2014.04.004"},{"key":"ref034","doi-asserted-by":"publisher","DOI":"10.1177\/1533317519828046"},{"key":"ref035","doi-asserted-by":"publisher","DOI":"10.3389\/fninf.2016.00030"},{"key":"ref036","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9061715"},{"key":"ref037","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.24835"},{"key":"ref038","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0730-07.2007"},{"key":"ref039","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awt065"},{"key":"ref040","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.8178"},{"key":"ref041","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.3.486"},{"key":"ref042","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci2040553"},{"key":"ref043","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awr138"},{"key":"ref044","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2012.00338"},{"key":"ref045","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2009.07.018"},{"key":"ref046","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.12803"},{"key":"ref047","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aww243"},{"key":"ref048","first-page":"1501","volume":"19","author":"Gunning-Dixon FM","year":"1998","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref049","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2003.07.003"},{"key":"ref050","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200207020-00010"},{"key":"ref051","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.13362"},{"key":"ref052","doi-asserted-by":"publisher","DOI":"10.1097\/WAD.0b013e3181999e92"},{"key":"ref053","doi-asserted-by":"publisher","DOI":"10.3390\/biomimetics8010059"},{"key":"ref054","doi-asserted-by":"publisher","DOI":"10.1177\/26331055231161625"},{"key":"ref055","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3401-04.2005"},{"key":"ref056","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg268"},{"key":"ref057","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2015.06.026"},{"key":"ref058","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.1037347"},{"key":"ref059","doi-asserted-by":"publisher","DOI":"10.1016\/j.apnr.2014.12.007"}],"container-title":["Journal of Alzheimer's Disease Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/ADR-230101","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3233\/ADR-230101","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/ADR-230101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:57:46Z","timestamp":1777370266000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/ADR-230101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,9]]},"references-count":59,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1,9]]}},"alternative-id":["10.3233\/ADR-230101"],"URL":"https:\/\/doi.org\/10.3233\/adr-230101","relation":{},"ISSN":["2542-4823","2542-4823"],"issn-type":[{"value":"2542-4823","type":"print"},{"value":"2542-4823","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,9]]}}}