{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:13:52Z","timestamp":1777392832443,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T00:00:00Z","timestamp":1704758400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer's Disease Reports"],"published-print":{"date-parts":[[2024,1,9]]},"abstract":"<jats:p>The prodromal stage of Lewy body dementia includes a mild cognitive impairment with visual processing and\/or attention-executive deficits. A clinical presentation with progressive visual loss is indeed seldom reported and can be misleading with a posterior cortical atrophy disease. While the neurodegeneration at the occipital cortex can only partially explain the visual disturbances of Lewy body dementia, more recently a retinal dysfunction has been suggested by preliminary optical coherence tomography and autoptic findings. Herein, we present a case of a mild cognitive impairment with Lewy bodies, who presented initially with visual disturbances and signs of both retinal and cortical visual processing dysfunction. A complete neuropsychological, neurophysiological and brain imaging assessment highlighted a prominent ventral visual pathway involvement. This report provides first that the prodromal stage of Lewy body dementia can manifest as a primarily progressive visual loss, second that the involvement of visual pathway, particularly the ventral stream, can be detectable from the retinal to the cortical level.<\/jats:p>","DOI":"10.3233\/adr-230176","type":"journal-article","created":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T11:11:35Z","timestamp":1709291495000},"page":"363-369","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Retinal and Cortical Visual Processing Dysfunction in a Case of Mild Cognitive Impairment with Lewy Bodies: A Case Report"],"prefix":"10.1177","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9539-5150","authenticated-orcid":false,"given":"Giulia","family":"Perini","sequence":"first","affiliation":[{"name":"Clinical Neuroscience Unit of Dementia, Dementia Research Center, IRCCS Mondino Foundation, Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Cotta Ramusino","sequence":"additional","affiliation":[{"name":"Clinical Neuroscience Unit of Dementia, Dementia Research Center, IRCCS Mondino Foundation, Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Conca","sequence":"additional","affiliation":[{"name":"Clinical Neuroscience Unit of Dementia, Dementia Research Center, IRCCS Mondino Foundation, Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Cosentino","sequence":"additional","affiliation":[{"name":"Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy"},{"name":"Translational Neurophysiology Research Unit, IRCCS Mondino Foundation, Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa Maria","family":"Farina","sequence":"additional","affiliation":[{"name":"Neuroradiology Department, Advanced Imaging and Radiomics Center, IRCCS Mondino Foundation, Pavia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Costa","sequence":"additional","affiliation":[{"name":"Clinical Neuroscience Unit of Dementia, Dementia Research Center, IRCCS Mondino Foundation, Pavia, Italy"},{"name":"Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Farina","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,2,29]]},"reference":[{"key":"ref001","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-018-1016-8"},{"key":"ref002","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000009323"},{"key":"ref003","doi-asserted-by":"publisher","DOI":"10.1111\/j.1444-0938.2012.00770.x"},{"key":"ref004","doi-asserted-by":"publisher","DOI":"10.1037\/a0016834"},{"key":"ref005","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.111.099432"},{"key":"ref006","doi-asserted-by":"publisher","DOI":"10.1016\/j.neucli.2021.02.003"},{"key":"ref007","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2014.04.027"},{"key":"ref008","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27728"},{"key":"ref009","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000178896.44905.33"},{"key":"ref010","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp068"},{"key":"ref011","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.1996.tb00423.x"},{"key":"ref012","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-012-1130-x"},{"key":"ref013","doi-asserted-by":"publisher","DOI":"10.1159\/000117297"},{"key":"ref014","first-page":"1","volume":"12","author":"Carlesimo GA","year":"2002","journal-title":"Nuova Riv Neurol"},{"key":"ref015","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-007-0845-6"},{"key":"ref016","first-page":"477","volume":"4","author":"Novelli G","year":"1986","journal-title":"Arch Psicol Neurol Psichiatr"},{"key":"ref017","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-012-1181-z"},{"key":"ref018","first-page":"1","volume":"8","author":"Spinnler H","year":"1987","journal-title":"Ital J Neurol Sci"},{"key":"ref019","doi-asserted-by":"publisher","DOI":"10.1007\/BF01997792"},{"key":"ref020","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-005-0443-4"},{"key":"ref021","unstructured":"Barletta-RodolfiC, GaspariniF, GhidoniE (2011) Kit del Neuropsicologo Italiano. 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