{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T13:05:50Z","timestamp":1777467950943,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BD"],"published-print":{"date-parts":[[2022,1,20]]},"abstract":"<jats:p>The rate of metastasis to the central nervous system is high in human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer patients. Metastatic cauda equina tumors are characterized by rapid progression of symptoms, thus signifying the requirement of their early treatment. However, these tumors are rarely reported, and their optimal treatment options have not been established yet. Here, we report a case study of a patient with HER2-positive breast cancer that metastasized to the cauda equina. The patient underwent urgent surgery to relieve the spinal cord compression. The pain in her back and lower limbs was greatly reduced. Unfortunately, her ability to walk did not improve sufficiently. Overall, surgical treatment may be a favorable option to improve a patient\u2019s quality of life.<\/jats:p>","DOI":"10.3233\/bd-210032","type":"journal-article","created":{"date-parts":[[2022,1,25]],"date-time":"2022-01-25T13:41:27Z","timestamp":1643118087000},"page":"155-161","source":"Crossref","is-referenced-by-count":3,"title":["Intramedullary spinal cord metastasis to the cauda equina in a patient with HER2-positive metastatic breast cancer: A case report"],"prefix":"10.1177","volume":"41","author":[{"given":"Naohiko","family":"Oki","sequence":"first","affiliation":[{"name":", Keio University School of Medicine, , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirohito","family":"Seki","sequence":"additional","affiliation":[{"name":", Saitama Medical Center, , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Sakurai","sequence":"additional","affiliation":[{"name":", Saitama Medical Center, , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yosuke","family":"Horiuchi","sequence":"additional","affiliation":[{"name":", Saitama Medical Center, , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Kodaka","sequence":"additional","affiliation":[{"name":", Saitama Medical Center, , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Shimizu","sequence":"additional","affiliation":[{"name":", Saitama Medical Center, , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"10.3233\/BD-210032_ref1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1634\/theoncologist.2011-0212","article-title":"Correlation between quantitative HER-2 protein expression and risk for brain metastases in HER-2+ advanced breast cancer patients receiving trastuzumab-containing therapy","volume":"17","author":"Duchnowska","year":"2012","journal-title":"Oncologist"},{"key":"10.3233\/BD-210032_ref2","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1007\/PL00014587","article-title":"Spinal intramedullary metastases. 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