{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T13:05:58Z","timestamp":1777467958462,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BD"],"published-print":{"date-parts":[[2022,1,24]]},"abstract":"<jats:p>BACKGROUND: The implementation of digital breast tomosynthesis has increased the detection of architectural distortion (AD). Managing this finding may be experienced as a clinical dilemma in daily practice. Breast Contrast-Enhanced MRI (CE-BMR) is a known modality in case of problem-solving tool for mammographic abnormalities. However, the data about AR and CE-BMR are scant. OBJECTIVE: The purpose was to estimate the benefit of CE-BMR in the setting of architectural distortion detected mammographically through a systematic review and meta-analysis of the literature. METHODS: A search of MEDLINE and EMBASE databases were conducted in 2020. Based on the PRISMA guidelines, an analysis was performed using the chi-square test of independence to determine if there was a significant association between the result of the test (positive or negative) and the participant condition (malignant or non-malignant). RESULTS: Four studies were available. The negative predictive value (NPV) was 98.3% to 100%. The result of the chi-square indicated that there was significant association between the participant test result and the participant condition for the included publications (X(1,175)2=\u00a084.051, p =\u00a00.0001). CONCLUSIONS: The high NPV could allow for deferral of a biopsy in favor of a short-interval imaging follow-up in the setting of a negative CE-BMR.<\/jats:p>","DOI":"10.3233\/bd-210045","type":"journal-article","created":{"date-parts":[[2022,1,25]],"date-time":"2022-01-25T13:41:27Z","timestamp":1643118087000},"page":"205-214","source":"Crossref","is-referenced-by-count":9,"title":["Meta-analysis: Architectural distortion and breast MRI"],"prefix":"10.1177","volume":"41","author":[{"given":"Romuald","family":"Ferre","sequence":"first","affiliation":[{"name":", , , Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cherie M.","family":"Kuzmiak","sequence":"additional","affiliation":[{"name":"Department of Radiology, UNC School of Medicine, , , 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