{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T13:07:09Z","timestamp":1777468029863,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BD"],"published-print":{"date-parts":[[2023,12,11]]},"abstract":"<jats:p>Lymphedema (LE) in a breast cancer patient usually results from axillary lymph node dissection, sentinel lymph node biopsy, and\/or axillary radiotherapy. Although lymphatic obstruction and consequent LE can occur due to axillary lymph node involvement, such presentation in breast cancer patients has rarely been reported. This report describes the case of a 50-year-old lady with right breast carcinoma who presented with right upper limb lymphedema. Surprisingly, she did not have any bulky axillary lymphadenopathy that could have accounted for lymphedema of the upper limb, but a suspicious breast mass was present on clinical examination. Diagnosis of breast cancer on clinical examination can be challenging in such patients due to breast edema and careful imaging of the breast and axilla with appropriate imaging tools (mammogram, ultrasound, MRI, PET mammography) should be resorted to before excluding malignancy. Lymphoscintigraphy confirmed the findings of lymphedema in the right upper limb and revealed uptake in the epitrochlear lymph nodes of the contralateral limb suggesting that she might had pre-existing widespread \u201csubclinical lymphedema\u201d which presented as \u201cclinical lymphedema\u201d in right upper limb after axillary lymph node\/lymphatic involvement by right breast carcinoma.<\/jats:p>","DOI":"10.3233\/bd-230022","type":"journal-article","created":{"date-parts":[[2023,12,12]],"date-time":"2023-12-12T11:22:59Z","timestamp":1702380179000},"page":"395-399","source":"Crossref","is-referenced-by-count":0,"title":["Breast carcinoma presenting with upper limb lymphedema \u2014 A rare case"],"prefix":"10.1177","volume":"42","author":[{"given":"Chandan Kumar","family":"Jha","sequence":"first","affiliation":[{"name":", All India Institute of Medical Sciences, , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Upasna","family":"Sinha","sequence":"additional","affiliation":[{"name":", All India Institute of Medical Sciences, , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mainak","family":"Sinha","sequence":"additional","affiliation":[{"name":", All India Institute of Medical Sciences, , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prashant Kumar","family":"Singh","sequence":"additional","affiliation":[{"name":", All India Institute of Medical Sciences, , India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"issue":"1","key":"10.3233\/BD-230022_ref1","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1055\/s-0038-1635117","article-title":"Diagnosis and staging of lymphedema","volume":"32","author":"Greene","year":"2018","journal-title":"Semin Plast Surg"},{"key":"10.3233\/BD-230022_ref2","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.breast.2016.04.011","article-title":"Risk factors for lymphoedema in women with breast cancer: A large prospective cohort","volume":"28","author":"Kilbreath","year":"2016","journal-title":"Breast"},{"issue":"20","key":"10.3233\/BD-230022_ref3","doi-asserted-by":"publisher","first-page":"2341","DOI":"10.1200\/JCO.19.02896","article-title":"Breast cancer- related lymphedema: risk factors, screening, management, and the impact of locoregional treatment","volume":"38","author":"McLaughlin","year":"2020","journal-title":"J Clin Oncol"},{"issue":"3","key":"10.3233\/BD-230022_ref4","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1007\/s12282-018-0830-3","article-title":"The incidence and risk factors of related lymphedema for breast cancer survivors post-operation: a 2-year follow-up prospective cohort study","volume":"25","author":"Zou","year":"2018","journal-title":"Breast Cancer"},{"issue":"5","key":"10.3233\/BD-230022_ref5","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1007\/s12282-020-01088-x","article-title":"Risk factors for breast cancer-related lymphedema: correlation with docetaxel administration","volume":"27","author":"Aoishi","year":"2020","journal-title":"Breast Cancer"},{"issue":"5","key":"10.3233\/BD-230022_ref6","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1007\/s11606-006-0077-0","article-title":"Breast cancer presenting as unilateral arm edema","volume":"22","author":"Zakaria","year":"2007","journal-title":"J Gen Intern Med"},{"issue":"9","key":"10.3233\/BD-230022_ref7","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/j.revmed.2007.02.017","article-title":"Lymphoed\u00e8me du membre sup\u00e9rieur r\u00e9v\u00e9lant un cancer du sein [Upper limb lymphedema revealing breast cancer]","volume":"28","author":"Vignes","year":"2007","journal-title":"Rev Med Interne"},{"issue":"1","key":"10.3233\/BD-230022_ref8","first-page":"3","article-title":"The diagnosis and treatment of peripheral lymphedema: 2020 Consensus Document of the International Society of Lymphology","volume":"53","author":"Executive Committee of the International Society of Lymphology","year":"2020","journal-title":"Lymphology"},{"issue":"6","key":"10.3233\/BD-230022_ref9","doi-asserted-by":"publisher","first-page":"1697","DOI":"10.1148\/radiographics.20.6.g00nv141697","article-title":"Advances in imaging of lymph flow disorders","volume":"20","author":"Witte","year":"2000","journal-title":"Radiographics"},{"issue":"2","key":"10.3233\/BD-230022_ref10","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1111\/bjd.12024","article-title":"Primary upper-limb lymphoedema","volume":"168","author":"Vignes","year":"2013","journal-title":"Br J Dermatol"}],"container-title":["Breast Disease"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/BD-230022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:32:36Z","timestamp":1777383156000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/BD-230022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,11]]},"references-count":10,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3233\/bd-230022","relation":{},"ISSN":["0888-6008","1558-1551"],"issn-type":[{"value":"0888-6008","type":"print"},{"value":"1558-1551","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,11]]}}}