{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:12:41Z","timestamp":1777464761733,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Bio-Medical Materials and Engineering"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:p>We assessed the role of F-18 FDG PET\/CT in evaluating isolated extra-axillary lymph node recurrences in postoperative breast cancer patients and its prognostic value on clinical outcome. We reviewed PET\/CT scans of postoperative breast cancer patients performed at our institution between July 2003 and February 2012. We recorded PET\/CT findings, clinicopathologic variables and treatment modalities. We analyzed metabolic parameters from PET\/CT and clinicopathologic variables with respect to progression free survival (PFS). A total of 3561 PET\/CT scans were performed in 1906 postoperative breast cancer patients with a median interval of 43 month from curative surgery. Fifty seven patients (2.99%) demonstrated isolated extra-axillary nodal recurrences (n=85) on PET\/CT (internal mammary node recurrences in 28, supraclavicular 24, infraclavicular 4, interpectoral 8, cervical 12, and mediastinal 9).The median SUVmax was 7.8 (range, 1.8\u223c19.0), and the median node size was 15 mm (range, 6\u223c38 mm). All recurrences were nonpalpable. Based on PET\/CT findings, 53 out of 57 patients with extra-axillary node recurrences underwent subsequent chemotherapy\/radiation therapy. The estimated 3-year PFS rate was 48.6%. Cutoff points of SUVmax 2.7 and size 14 mm were the best discriminative values for predicting clinical outcome. SUVmax and size of extra-axillary nodal recurrences were significantly correlated to PFS on univariate and multivariate analyses (p&lt;0.001 and p=0.019, respectively).<\/jats:p>","DOI":"10.3233\/bme-130918","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T14:44:48Z","timestamp":1575297888000},"page":"1173-1184","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Value of F-18 FDG PET\/CT in detection and prognostication of isolated extra-axillary lymph node recurrences in postoperative breast cancer"],"prefix":"10.1177","volume":"24","author":[{"given":"Jin Kyoung","family":"Oh","sequence":"first","affiliation":[{"name":"Department of Radiology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong An","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Radiology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeon Sil","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiation oncology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hae Myung","family":"Jeon","sequence":"additional","affiliation":[{"name":"Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Hoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Ha","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Radiology, St. Vincent Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo Kyo","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,1]]},"container-title":["Bio-Medical Materials and Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/BME-130918","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/BME-130918","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:24:06Z","timestamp":1777382646000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/BME-130918"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.3233\/BME-130918"],"URL":"https:\/\/doi.org\/10.3233\/bme-130918","relation":{},"ISSN":["0959-2989","1878-3619"],"issn-type":[{"value":"0959-2989","type":"print"},{"value":"1878-3619","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1]]}}}