{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T02:11:37Z","timestamp":1791252697260,"version":"4.1.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Bio-Medical Materials and Engineering"],"published-print":{"date-parts":[[2015,2]]},"abstract":"BACKGROUND: Non-union of long bones is still a current problem in traumatology. Although corticocancellous bone autograft remains the usual procedure for the treatment of non-union, innovative therapies such as, percutaneous autologous concentrated bone marrow grafting (PABMG), are now appearing.<\/jats:p>\n MATERIAL AND METHODS: Over a period of 8 years, 45 non-union of long bones were treated by PABMG in the Department of Orthopaedic and Traumatologic Surgery (University Hospital of Nancy, France): 26 tibiae, 16 femurs, 3 humeri. Efficiency was evaluated by clinical criteria: full weight-bearing without pain, absence of motion at non-union site, and radiological criteria: healing of 3 corticales out of 4.<\/jats:p>\n RESULTS: Eighteen out of 28 non-unions at the tibia were healed (69%), 10 at the femur (63%), but none was noticed at the humerus. Some pejorative prognosis factors were noted such as: tobacco, alcohol abuse, diabetes and history of infection at the fracture site. An earlier grafting improved the success rate. The number of CFU-F (Colony Forming Unit Fibroblastic) affected the healing time more than the healing rate.<\/jats:p>\n CONCLUSION: The procedure, even though a little invasive, enables the healing of non-union in two out of three cases with less morbidity than conventional procedures. This procedure fits perfectly into the therapeutic arsenal of non-union.<\/jats:p>","DOI":"10.3233\/bme-141235","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T15:04:06Z","timestamp":1575299046000},"page":"187-197","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Percutaneous autologous bone marrow injection for treatment of delayed and non-union of long bone: A retrospective study of 45 cases"],"prefix":"10.1177","volume":"25","author":[{"given":"Jean-Baptiste","family":"Gross","sequence":"first","affiliation":[{"name":"Service de Chirurgie Orthop\u00e9dique et Traumatologique, H\u00f4pital Central, Nancy, France"},{"name":"Universit\u00e9 de Lorraine, Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Diligent","sequence":"additional","affiliation":[{"name":"Service de Chirurgie Orthop\u00e9dique et Traumatologique, H\u00f4pital Central, Nancy, France"},{"name":"Universit\u00e9 de Lorraine, Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dani\u00e8le","family":"Bensoussan","sequence":"additional","affiliation":[{"name":"CNRS, UMR 7365, Biopole, Facult\u00e9 de M\u00e9decine, Vand\u0153uvre-l\u00e8s-Nancy, France"},{"name":"CHU de Nancy, Unit\u00e9 de Th\u00e9rapie Cellulaire et Tissulaire (UTCT) (FR CNRS-INSERM-UHP-CHU 3209), H\u00f4pitaux de Brabois, Vand\u0153uvre-l\u00e8s-Nancy, France"},{"name":"Universit\u00e9 de Lorraine, Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Galois","sequence":"additional","affiliation":[{"name":"Service de Chirurgie Orthop\u00e9dique et Traumatologique, H\u00f4pital Central, Nancy, France"},{"name":"Universit\u00e9 de Lorraine, Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Fran\u00e7ois","family":"Stoltz","sequence":"additional","affiliation":[{"name":"CNRS, UMR 7365, Biopole, Facult\u00e9 de M\u00e9decine, Vand\u0153uvre-l\u00e8s-Nancy, France"},{"name":"CHU de Nancy, Unit\u00e9 de Th\u00e9rapie Cellulaire et Tissulaire (UTCT) (FR CNRS-INSERM-UHP-CHU 3209), H\u00f4pitaux de Brabois, Vand\u0153uvre-l\u00e8s-Nancy, France"},{"name":"Universit\u00e9 de Lorraine, Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Mainard","sequence":"additional","affiliation":[{"name":"Service de Chirurgie Orthop\u00e9dique et Traumatologique, H\u00f4pital Central, Nancy, France"},{"name":"CNRS, UMR 7365, Biopole, Facult\u00e9 de M\u00e9decine, Vand\u0153uvre-l\u00e8s-Nancy, France"},{"name":"Universit\u00e9 de Lorraine, Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,2]]},"container-title":["Bio-Medical Materials and Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/BME-141235","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/BME-141235","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:25:00Z","timestamp":1777382700000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/BME-141235"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":0,"journal-issue":{"issue":"1_suppl","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["10.3233\/BME-141235"],"URL":"https:\/\/doi.org\/10.3233\/bme-141235","relation":{"is-cited-by":[{"id-type":"doi","id":"10.5312\/wjo.v8.i2.87","asserted-by":"object"},{"id-type":"doi","id":"10.1007\/s00264-016-3267-3","asserted-by":"object"}]},"ISSN":["0959-2989","1878-3619"],"issn-type":[{"value":"0959-2989","type":"print"},{"value":"1878-3619","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2]]}}}