{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:23:56Z","timestamp":1777465436335,"version":"3.51.4"},"reference-count":0,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Bio-Medical Materials and Engineering"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:label>Abstract<\/jats:label>\n                  <jats:p>\n                    In this paper, the hemoglobin (Hb) re-released from red blood cells (RBCs) and whole blood of 7 carcinoma patients were studied by using electrophoresis release test (ERT), which was established by our lab. Among the 7 carcinoma patients, the re-released Hb was distinctively increased from an intrahepatic bile duct carcinoma patient during one-dimension isotonic ERT. Different from the others, the result of double-dimension Hb re-release of this intrahepatic bile duct carcinoma patient showed that not only HbA but also HbA\n                    <jats:sub>2<\/jats:sub>\n                    could be re-released from both RBCs and whole blood. The result of isotonic &amp; hypotonic ERT which was performed at room temperature showed that more Hb could be re-released from both RBCs and whole blood of the intrahepatic bile duct carcinoma patient than that of the normal control. After keeping the samples at 37\u00b0C for 1 hour, the re-released Hb from RBCs could still be found more than that of the normal control, but was disappeared completely from the whole blood sample. To our surprise, when the isotonic &amp; hypotonic ERT was repeated 2 days later at 37\u00b0C, the re-released Hb from RBCs of the intrahepatic bile duct carcinoma patient was increased only in tube 4-6, and disappeared in the other tube. Further mechanism research work cannot be continued because of the patient\u2019s leave, but ERT is speculated to be a useful and effective technology to observe the physiological or pathological change of RBCs, blood or body in the future.\n                  <\/jats:p>","DOI":"10.3233\/bme-151510","type":"journal-article","created":{"date-parts":[[2015,8,17]],"date-time":"2015-08-17T15:51:18Z","timestamp":1439826678000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Abnormal increased re-released Hb from RBCs of an intrahepatic bile duct carcinoma patient was detected by electrophoresis release test"],"prefix":"10.1177","volume":"26","author":[{"given":"Yan","family":"Su","sequence":"first","affiliation":[{"name":"Laboratory of Hemoglobin, Baotou Medical College, Baotou, 014060, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisha","family":"Han","sequence":"additional","affiliation":[{"name":"Laboratory of Hemoglobin, Baotou Medical College, Baotou, 014060, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijun","family":"Gao","sequence":"additional","affiliation":[{"name":"Laboratory of Hemoglobin, Baotou Medical College, Baotou, 014060, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Invasive Technology, the Seventh Hospital of Baotou, Baotou, 014010, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaorong","family":"Sun","sequence":"additional","affiliation":[{"name":"Laboratory of Hemoglobin, Baotou Medical College, Baotou, 014060, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaxin","family":"Li","sequence":"additional","affiliation":[{"name":"Laboratory of Hemoglobin, Baotou Medical College, Baotou, 014060, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenbin","family":"Qin","sequence":"additional","affiliation":[{"name":"Laboratory of Hemoglobin, Baotou Medical College, Baotou, 014060, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,2]]},"container-title":["Bio-Medical Materials and Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/BME-151510","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3233\/BME-151510","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:25:44Z","timestamp":1777382744000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3233\/BME-151510"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":0,"journal-issue":{"issue":"1_suppl","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["10.3233\/BME-151510"],"URL":"https:\/\/doi.org\/10.3233\/bme-151510","relation":{},"ISSN":["0959-2989","1878-3619"],"issn-type":[{"value":"0959-2989","type":"print"},{"value":"1878-3619","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2]]}}}