{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:10:21Z","timestamp":1777464621517,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Bio-Medical Materials and Engineering"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Surface modification of metallic implants is critical for improving the clinical performance of the dental and orthopedic devices. Bioactive glasses exhibit different levels of cellular function and physicochemical behavior; however, there have been few previous studies on the effect of constituents of the bioactive glasses on the in vitro osteogenic activity and corrosion resistance of apatite-based coatings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>OBJECTIVE:<\/jats:title>\n                    <jats:p>\n                      The objective of this work was to investigate the effect of SiO\n                      <jats:sub>2<\/jats:sub>\n                      , CaO, Na\n                      <jats:sub>2<\/jats:sub>\n                      O, and P\n                      <jats:sub>2<\/jats:sub>\n                      O\n                      <jats:sub>5<\/jats:sub>\n                      on plasma-sprayed apatite coatings on Ti alloy substrates for tailoring the properties of implants making them suitable for clinical applications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>The corrosion potential and corrosion current of various coatings in simulated body fluid (SBF) were examined. MG63 cell proliferation, differentiation, and mineralization of plasma-sprayed apatite-matrix coatings were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      The SiO\n                      <jats:sub>2<\/jats:sub>\n                      and CaO-containing HA (HSC) coating had a higher corrosion potential than the other three coatings, while SiO\n                      <jats:sub>2<\/jats:sub>\n                      -containing HA (HS) coating displayed the highest corrosion current among all coatings. The effect of the oxides on cell functions followed the order SiO\n                      <jats:sub>2<\/jats:sub>\n                      &gt; CaO &gt; P\n                      <jats:sub>2<\/jats:sub>\n                      O\n                      <jats:sub>5<\/jats:sub>\n                      &gt; Na\n                      <jats:sub>2<\/jats:sub>\n                      O in terms of cell attachment, proliferation, differentiation, and mineralization.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>The flexibility in oxide doping may allow for the tunable biological properties and corrosion-resistant ability of the apatite coatings.<\/jats:p>\n                  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Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui-Wen","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Chung Shan Medical University Hospital,  Taichung City 402, Taiwan"},{"name":"School of Dentistry, Chung Shan Medical University,  Taichung City 402, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Feng","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Chung Shan Medical University Hospital,  Taichung City 402, Taiwan"},{"name":"School of Dentistry, Chung Shan Medical University,  Taichung City 402, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinn-Jyh","family":"Ding","sequence":"additional","affiliation":[{"name":"Institute of Oral Science, Chung Shan Medical University,  Taichung City 402, Taiwan"},{"name":"Department of Stomatology, Chung Shan Medical University Hospital,  Taichung City 402, 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