{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T10:25:11Z","timestamp":1791973511998,"version":"4.4.0"},"reference-count":28,"publisher":"SAGE Publications","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMR"],"published-print":{"date-parts":[[2022,3,7]]},"abstract":"<jats:p>BACKGROUND: Fluoroscopy-guided caudal epidural steroid injection (EDSI) is an option for conservative treatment of low back pain and sciatica; however, repeated exposure to radiation is a concern. With the blind technique, the needle misplacement rate is 30%; hence, ultrasound-guided caudal EDSI is a favored option. OBJECTIVE: To determine the efficacy of ultrasound-guided EDSI for low back pain and sciatica. METHODS: One hundred and ten patients with low back pain and sciatica who were unresponsive to conservative treatment, were prospectively recruited. Ultrasound-guided caudal EDSI was administered at 0, 3, and 6 weeks. Visual Analog Scale (VAS) score was recorded at 0, 2, 4, 12, and 24 weeks. Patients completed the Roland-Morris Disability Questionnaire (RMDQ) at pre-injection and 24 weeks post-injection. RESULTS: VAS was significantly reduced at 2, 4, 12, and 24 weeks (p&lt; 0.01). At 2, 4, 12, and 24 weeks after injection, 20%, 26%, 74%, and 83% of patients displayed &gt; 50% VAS reduction, respectively. The mean pre-injection RMDQ score was 15 and that post-injection at 24 weeks was 7 (p&lt; 0.01). The majority of patients had &gt; 50% reduction in the RMDQ score. CONCLUSIONS: Ultrasound-guided EDSI was safe and efficacious for low back pain and sciatica treatment at the intermediate follow-up.<\/jats:p>","DOI":"10.3233\/bmr-200224","type":"journal-article","created":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T12:42:11Z","timestamp":1627994531000},"page":"317-322","source":"Crossref","is-referenced-by-count":7,"title":["Efficacy and safety of ultrasound-guided caudal epidural steroid injection in patients with low back pain and sciatica"],"prefix":"10.1177","volume":"35","author":[{"given":"Kasisin","family":"Klunklin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apiruk","family":"Sangsin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taninnit","family":"Leerapun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"10.3233\/BMR-200224_ref1","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1097\/00007632-199701010-00013","article-title":"Management of chronic nonspecific low back pain in primary care: a descriptive study","volume":"22","author":"Van Tulder","year":"1997","journal-title":"Spine (Phila Pa 1976)."},{"key":"10.3233\/BMR-200224_ref2","first-page":"613","article-title":"Degenerative lumbar spinal stenosis in older people: current treatment options","volume":"110","author":"Kalff","year":"2013","journal-title":"Dtsch Arztebl Int."},{"key":"10.3233\/BMR-200224_ref3","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.jbspin.2005.03.004","article-title":"Pathophysiology of disk-related low back pain and sciatica. 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