{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:32:17Z","timestamp":1777465937643,"version":"3.51.4"},"reference-count":54,"publisher":"SAGE Publications","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMR"],"published-print":{"date-parts":[[2022,9,2]]},"abstract":"<jats:p>BACKGROUND: Pain sensitization may be one of the mechanisms contributing to chronic low back pain (CLBP). OBJECTIVE: To evaluate the association between visceral fat, CLBP, and central sensitization (CS); describe the relationship between low back pain (LBP) intensity and CS; and identify possible correlation between visceral fat and LBP intensity. METHODS: Patients with CLBP were divided using their CS inventory (CSI) scores into low- (CSI &lt; 40) and high-CSI (CSI \u2a7e 40) subgroups. We compared computed tomography (CT) measurements and scores for association with pain according to the visual analogue scale (VAS) between the two groups. RESULTS: The low-CSI and the high-CSI groups had 47 patients (67.1%; 21 men, 26 women) and 23 patients (32.9%; 11 men and 12 women), respectively. The high-CSI group had a significantly higher mean VAS score (p&lt; 0.01) and estimated mean visceral fat area (p&lt; 0.05) than the low-CSI group. There was a moderate positive correlation between VAS score and visceral fat (standardised partial regression coefficient: 0.659, p&lt; 0.01) in the high-CSI group according to multiple linear regression analysis adjusted for age and sex. CONCLUSIONS: Visceral fat is associated with CLBP, regardless of sex or age, and may be a potential therapeutic target for CLBP with CS.<\/jats:p>","DOI":"10.3233\/bmr-210124","type":"journal-article","created":{"date-parts":[[2022,2,22]],"date-time":"2022-02-22T13:17:43Z","timestamp":1645535863000},"page":"1035-1041","source":"Crossref","is-referenced-by-count":6,"title":["Associations between visceral fat chronic low back pain and central sensitization in patients with lumbar spinal stenosis"],"prefix":"10.1177","volume":"35","author":[{"given":"Izaya","family":"Ogon","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Teramoto","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, Sapporo, 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