{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:32:04Z","timestamp":1777465924570,"version":"3.51.4"},"reference-count":46,"publisher":"SAGE Publications","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMR"],"published-print":{"date-parts":[[2022,11,12]]},"abstract":"<jats:p>BACKGROUND: Kyphoplasty for osteoporotic vertebral compression fractures (OVCF) is a short but painful intervention. Different anesthetic techniques have been proposed to control pain during kyphoplasty; however, all have limitations. OBJECTIVE: To compare the effectiveness and safety of ultrasound-guided thoracic paravertebral block with local anesthesia for percutaneous kyphoplasty (PKP). METHODS: In this prospective study, non-randomized patients with OVCF undergoing PKP received either ultrasound-guided thoracic paravertebral block (group P) or local anesthesia (group L). Perioperative pain, satisfaction with anesthesia, and complications were compared between the groups. RESULTS: Mean intraoperative (T1\u2013T4) perioperative visual analog scale (VAS) scores were significantly lower in group P than in group L (2 [1\u20133] vs. 3 [2\u20134], 2 [2\u20133] vs. 4 [2\u20134], 2 [2\u20133] vs. 5 [3\u20135], and 3 [2\u20133] vs. 5 [3\u20135], respectively; P&lt; 0.05). Investigators\u2019 satisfaction scores, patients\u2019 anesthesia satisfaction scores, and anesthesia re-administration intention rate were significantly higher in group P than in group L (4 [3\u20135] vs. 3 [2\u20134], 2 [2\u20133] vs. 2 [1\u20133], 90.63% vs. 69.70%; P&lt; 0.05). There was no significant intergroup difference in complications. CONCLUSIONS: Ultrasound-guided thoracic paravertebral block has similar safety to and better effectiveness than local anesthesia in PKP.<\/jats:p>","DOI":"10.3233\/bmr-210131","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T11:41:39Z","timestamp":1653046899000},"page":"1227-1235","source":"Crossref","is-referenced-by-count":7,"title":["Effectiveness and safety of ultrasound-guided thoracic paravertebral block versus local anesthesia for percutaneous kyphoplasty in patients with osteoporotic compression fracture"],"prefix":"10.1177","volume":"35","author":[{"given":"Xiqiang","family":"Zhong","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery, Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haijie","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yimin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengxuan","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojun","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaoqi","family":"He","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"issue":"1","key":"10.3233\/BMR-210131_ref1","first-page":"1","article-title":"The critical need to promote research of aging and aging-related diseases to improve health and longevity of the elderly population","volume":"6","author":"Jin","year":"2015","journal-title":"Aging Dis."},{"issue":"2","key":"10.3233\/BMR-210131_ref2","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.jocd.2020.05.007","article-title":"Osteoporotic vertebral fractures are common in hip fracture patients and are under-recognized","volume":"24","author":"Kelly","year":"2021","journal-title":"J Clin Densitom."},{"key":"10.3233\/BMR-210131_ref3","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1097\/BRS.0000000000001298","article-title":"Percutaneous vertebroplasty versus conservative treatment in aged patients with acute osteoporotic vertebral compression fractures: A prospective randomized controlled clinical study","volume":"41","author":"Yang","year":"2016","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.3233\/BMR-210131_ref4","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1227\/NEU.0000000000000953","article-title":"The aging of the global population: The changing epidemiology of disease and spinal disorders","volume":"77","author":"Fehlings","year":"2015","journal-title":"Neurosurgery."},{"key":"10.3233\/BMR-210131_ref5","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/mt.2013.221","article-title":"Serial transplantation and long-term engraftment of intra-arterially delivered clonally derived mesenchymal stem cells to injured bone marrow","volume":"22","author":"Lin","year":"2014","journal-title":"Mol Ther."},{"key":"10.3233\/BMR-210131_ref6","doi-asserted-by":"crossref","unstructured":"de Sire A, Ammendolia A, Gimigliano A, Tiberi R, Cisari C, Invernizzi M. 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