{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T10:09:30Z","timestamp":1781258970740,"version":"3.54.1"},"reference-count":31,"publisher":"SAGE Publications","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMR"],"published-print":{"date-parts":[[2023,1,4]]},"abstract":"<jats:p>BACKGROUND: Osteoporotic vertebral compression fractures (OVCFs) are the most common complication of osteoporosis, a worldwide disease that disturbs the elderly. OBJECTIVE: The purpose of the study was to comprehensively compare the clinical efficacy of unilateral percutaneous kyphoplasty (UPKP) and bilateral percutaneous kyphoplasty (BPKP) when treating OVCFs and evaluate their ability to maintain the outcomes in a 2-year follow-up. METHODS: From January 2015 to December 2016 a total of 79 patients with OVCFs were included in the study. They were divided into UPKP group and BPKP group. Subsequently, perioperative data, radiological outcomes, clinical outcomes, and complications were compared between two groups. The follow-up consultation was 3\u00a0months, 1\u00a0year, and 2\u00a0years after the operation. RESULTS: 37 of patients (14 males, 23 females) were allocated to the UPKP group and 42 patients (13 males, 29 females) were treated with BPKP. The duration of operation and injected cement volume were significantly higher in the BPKP group than those of the UPKP group. BPKP achieved significantly higher improvement in middle height and volume of the fractured vertebral body than UPKP did. There were significantly higher losses of anterior, middle height and volume of the fractured vertebral body in the UPKP group at 2-year follow-up than in the BPKP group. At the final follow-up, Oswestry Disability Index (ODI) of BPKP group was lower than that of UPKP group. CONCLUSION: Both UPKP and BPKP achieve satisfactory radiological and clinical outcomes when treating OVCFs. However, in a 2-year follow-up, BPKP maintains vertebral height restoration, volume of vertebral body, and ODI better than UPKP do.<\/jats:p>","DOI":"10.3233\/bmr-210225","type":"journal-article","created":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T12:05:24Z","timestamp":1659441924000},"page":"97-105","source":"Crossref","is-referenced-by-count":11,"title":["Bilateral percutaneous kyphoplasty achieves more satisfactory outcomes compared to unilateral percutaneous kyphoplasty in osteoporotic vertebral compression fractures: A comprehensive comparative study"],"prefix":"10.1177","volume":"36","author":[{"given":"Jianhua","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Haimen People\u2019s Hospital Affiliated to Nantong University, Nantong, Jiangsu, China"},{"name":"Department of Orthopaedic Surgery, Haimen People\u2019s Hospital Affiliated to Nantong University, Nantong, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Haimen People\u2019s Hospital Affiliated to Nantong University, Nantong, Jiangsu, China"},{"name":"Department of Orthopaedic Surgery, Haimen People\u2019s Hospital Affiliated to Nantong University, Nantong, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weikai","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongping","family":"Luo","sequence":"additional","affiliation":[{"name":"Orthopaedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huilin","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China"},{"name":"Orthopaedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China"},{"name":"Orthopaedic Institute, Medical College, Soochow University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"issue":"4","key":"10.3233\/BMR-210225_ref1","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1007\/s00198-012-2065-z","article-title":"Risk factors affecting progressive collapse of acute osteoporotic spinal fractures","volume":"24","author":"Ha","year":"2013","journal-title":"Osteoporos Int."},{"issue":"5","key":"10.3233\/BMR-210225_ref2","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1097\/BRS.0b013e3181b71bd1","article-title":"Twelve-months follow-up in forty-nine patients with acute\/semiacute osteoporotic vertebral fractures treated conservatively or with percutaneous vertebroplasty: a clinical randomized study","volume":"35","author":"Rousing","year":"2010","journal-title":"Spine (Phila Pa 1976)"},{"issue":"9319","key":"10.3233\/BMR-210225_ref3","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1016\/S0140-6736(02)08657-9","article-title":"Epidemiology and outcomes of osteoporotic fractures","volume":"359","author":"Cummings","year":"2002","journal-title":"Lancet."},{"key":"10.3233\/BMR-210225_ref4","doi-asserted-by":"crossref","unstructured":"de Sire A, Ammendolia A, Gimigliano A, Tiberi R, Cisari C, Invernizzi M. 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