{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:36:37Z","timestamp":1777466197845,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMR"],"published-print":{"date-parts":[[2024,9,3]]},"DOI":"10.3233\/bmr-245004","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T10:20:07Z","timestamp":1725963607000},"page":"1099-1101","source":"Crossref","is-referenced-by-count":0,"title":["A needless stab in the back: Do the benefits of using steroid injections for back and radicular pain outweigh its risks?"],"prefix":"10.1177","volume":"37","author":[{"given":"Dillan","family":"Mistry","sequence":"first","affiliation":[{"name":"Pinderfields General Hospital, Wakefield, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhikshitha","family":"Gokulakrishnan","sequence":"additional","affiliation":[{"name":"St James\u2019 Hospital, Leeds, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Ampat","sequence":"additional","affiliation":[{"name":"Royal Liverpool University Hospital, Liverpool, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"issue":"4","key":"10.3233\/BMR-245004_ref2","first-page":"122","article-title":"Insights in public health: perspectives on pain in the low back and neck: global burden, epidemiology, and management","volume":"73","author":"Vassilaki","year":"2014","journal-title":"Hawai\u2019i Journal of Medicine & Public Health: A Journal of Asia Pacific Medicine & Public Health."},{"issue":"11","key":"10.3233\/BMR-245004_ref3","doi-asserted-by":"publisher","first-page":"1796","DOI":"10.1136\/annrheumdis-2011-200731","article-title":"Exploring the cost-utility of stratified primary care management for low back pain compared with current best practice within risk-defined subgroups","volume":"71","author":"Whitehurst","year":"2012","journal-title":"Annals of the Rheumatic Diseases."},{"key":"10.3233\/BMR-245004_ref6","doi-asserted-by":"crossref","unstructured":"Iversen T, Solberg TK, Romner B, et al. Effect of caudal epidural steroid or saline injection in chronic lumbar radiculopathy: multicentre, blinded, randomised controlled trial. BMJ Publishing Group Ltd., 2011.","DOI":"10.1136\/bmj.d5278"},{"key":"10.3233\/BMR-245004_ref7","doi-asserted-by":"crossref","unstructured":"Epstein NE. The risks of epidural and transforaminal steroid injections in the Spine: Commentary and a comprehensive review of the literature. Medknow Publications & Media Pvt Ltd; 2013.","DOI":"10.4103\/2152-7806.109446"},{"issue":"8","key":"10.3233\/BMR-245004_ref8","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1097\/00007632-199704150-00004","article-title":"Low synthesis rate of type I procollagen is normalized during active back rehabilitation","volume":"22","author":"Hupli","year":"1997","journal-title":"Spine."},{"issue":"4","key":"10.3233\/BMR-245004_ref9","doi-asserted-by":"publisher","first-page":"4730","DOI":"10.3892\/mmr.2017.7178","article-title":"Collagen type II is downregulated in the degenerative nucleus pulposus and contributes to the degeneration and apoptosis of human nucleus pulposus cells","volume":"16","author":"Lian","year":"2017","journal-title":"Molecular Medicine Reports [Internet]."},{"issue":"1","key":"10.3233\/BMR-245004_ref10","first-page":"15","article-title":"Effect of corticosteroids on collagen synthesis","volume":"82","author":"Cohen","year":"1977","journal-title":"Surgery."},{"issue":"5","key":"10.3233\/BMR-245004_ref11","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1177\/0363546506290402","article-title":"Anti inflammatory steroids and collagen metabolism: glucocorticoid mediated alterations of prolyl hydroxylase activity and collagen synthesis","volume":"11","author":"Cutroneo","year":"1975","journal-title":"Molecular Pharmacology."},{"issue":"2","key":"10.3233\/BMR-245004_ref12","doi-asserted-by":"publisher","first-page":"e161","DOI":"10.1016\/j.asmr.2020.01.002","article-title":"Adverse impact of corticosteroids on rotator cuff tendon health and repair: A Systematic review of Basic science studies","volume":"2","author":"Puzzitiello","year":"2020","journal-title":"Arthroscopy, Sports Medicine, and Rehabilitation [Internet]."},{"key":"10.3233\/BMR-245004_ref13","doi-asserted-by":"publisher","DOI":"10.1002\/jsp2.1171"},{"key":"10.3233\/BMR-245004_ref14","doi-asserted-by":"crossref","unstructured":"Zheng N, Shabek N. Ubiquitin Ligases: Structure, Function, and Regulation. United States: ANNUAL REVIEWS INC; 2017, p. 129.","DOI":"10.1146\/annurev-biochem-060815-014922"},{"issue":"3","key":"10.3233\/BMR-245004_ref15","doi-asserted-by":"publisher","first-page":"e59726","DOI":"10.1371\/journal.pone.0059726","article-title":"PPA\u03b2\u2062\u03b4 regulates glucocorticoid- and sepsis-induced FOXO1 activation and muscle wasting","volume":"8","author":"Castillero","year":"2013","journal-title":"PloS One."},{"issue":"4","key":"10.3233\/BMR-245004_ref16","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1097\/MCO.0b013e32833a5107","article-title":"Corticosteroids and muscle wasting: role of transcription factors, nuclear cofactors, and hyperacetylation","volume":"13","author":"Hasselgren","year":"2010","journal-title":"Current Opinion in Clinical Nutrition and Metabolic Care."},{"issue":"2","key":"10.3233\/BMR-245004_ref17","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1308\/003588410X12518836438840","article-title":"Conservatively treated massive prolapsed discs: A 7-year follow-up","volume":"92","author":"Benson","year":"2010","journal-title":"Annals of the Royal College of Surgeons of England."},{"issue":"6","key":"10.3233\/BMR-245004_ref18","first-page":"1009","article-title":"Immune cascades in human intervertebral disc: the pros and cons","volume":"6","author":"Sun","year":"2013","journal-title":"International Journal of Clinical and Experimental Pathology."},{"issue":"1","key":"10.3233\/BMR-245004_ref19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13075-018-1743-4","article-title":"The inflammatory response in the regression of lumbar disc herniation","volume":"20","author":"Carla","year":"2018","journal-title":"Arthritis Research & Therapy."},{"key":"10.3233\/BMR-245004_ref20","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.01229"}],"container-title":["Journal of Back and Musculoskeletal Rehabilitation"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/BMR-245004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:27:57Z","timestamp":1777382877000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/BMR-245004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,3]]},"references-count":17,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.3233\/bmr-245004","relation":{},"ISSN":["1878-6324","1053-8127"],"issn-type":[{"value":"1878-6324","type":"electronic"},{"value":"1053-8127","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9,3]]}}}