{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:31:18Z","timestamp":1777480278060,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CBM"],"published-print":{"date-parts":[[2016,3,30]]},"DOI":"10.3233\/cbm-160586","type":"journal-article","created":{"date-parts":[[2016,4,5]],"date-time":"2016-04-05T11:55:05Z","timestamp":1459857305000},"page":"467-476","source":"Crossref","is-referenced-by-count":8,"title":["Rta-IgG as a biomarker for diagnosis and post treatment prognostic of nasopharyngeal carcinoma"],"prefix":"10.1177","volume":"16","author":[{"given":"Xiao-Feng","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, China"},{"name":"Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren-Quan","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, China"},{"name":"Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ran","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin-Min","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Shanghai Cancer Center, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi-Chun","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Shanghai Cancer Center, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, China"},{"name":"Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"10.3233\/CBM-160586_ref1","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1016\/S0140-6736(05)66698-6","article-title":"Nasopharyngeal carcinoma","volume":"365","author":"Wei","year":"2005","journal-title":"Lancet"},{"key":"10.3233\/CBM-160586_ref2","doi-asserted-by":"crossref","first-page":"114","DOI":"10.5732\/cjc.010.10377","article-title":"The prevalence and prevention of nasopharyngeal carcinoma in China","volume":"30","author":"Cao","year":"2011","journal-title":"Chin J Cancer"},{"key":"10.3233\/CBM-160586_ref3","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s40880-015-0019-5","article-title":"Impact of primary tumor volume and location on the prognosis of patients with locally recurrent nasopharyngeal carcinoma","volume":"34","author":"Tian","year":"2015","journal-title":"Chin J Cancer"},{"key":"10.3233\/CBM-160586_ref4","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1189\/jlb.0313173","article-title":"Innate immune responses against Epstein-Barr virus infection","volume":"94","author":"Chijioke","year":"2013","journal-title":"J Leukoc Biol"},{"key":"10.3233\/CBM-160586_ref5","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1002\/1097-0142(20011001)92:7<1872::AID-CNCR1704>3.0.CO;2-N","article-title":"Antibody Response to Epstein - Barr Virus Rta Protein in Patients with Nasopharyngeal Carcinoma","volume":"92","author":"Feng","year":"2001","journal-title":"Cancer"},{"key":"10.3233\/CBM-160586_ref6","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jviromet.2015.03.024","article-title":"Development of a time-resolved fluoro-immunoassay for Epstein-Barr virus viral capsid antigen IgA antibody in human serum","volume":"222","author":"Liang","year":"2015","journal-title":"J Virol Methods"},{"key":"10.3233\/CBM-160586_ref7","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.3892\/ol.2014.2286","article-title":"Combination of autoantibodies against NY-ESO-1 and viral capsid antigen immunoglobulin A for improved detection of nasopharyngeal carcinoma","volume":"8","author":"Peng","year":"2014","journal-title":"Oncology Lett"},{"key":"10.3233\/CBM-160586_ref8","first-page":"1201","article-title":"Diagnostic value of Epstein-Barr virus capsid antigen-IgA in nasopharyngeal carcinoma: A meta-analysis","volume":"123","author":"Li","year":"2010","journal-title":"Chin Med J"},{"key":"10.3233\/CBM-160586_ref9","first-page":"529","article-title":"Cancer stem-like cells in Epstein-Barr virus-associated nasopharyngeal carcinoma","volume":"33","author":"Lun","year":"2014","journal-title":"Chin J Cancer"},{"key":"10.3233\/CBM-160586_ref10","doi-asserted-by":"crossref","first-page":"4932","DOI":"10.1128\/JVI.03269-14","article-title":"Peptides designed to spatially depict the Epstein-Barr virus major virion glycoprotein gp350 neutralization epitope elicit antibodies that block virus-neutralizing antibody 72A1 interaction with the native gp350 molecule","volume":"89","author":"Tanner","year":"2015","journal-title":"J Virol"},{"key":"10.3233\/CBM-160586_ref11","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1089\/gtmb.2011.0012","article-title":"Detection of Epstein-Barr virus DNA in serum or plasma for nasopharyngeal cancer: a meta-analysis","volume":"15","author":"Liu","year":"2011","journal-title":"Genet Test Mol Biomarkers"},{"key":"10.3233\/CBM-160586_ref12","doi-asserted-by":"crossref","first-page":"e406","DOI":"10.3747\/co.20.1456","article-title":"Recurrent nasopharyngeal carcinoma: a clinical dilemma and challenge","volume":"20","author":"Xu","year":"2013","journal-title":"Curr Oncol"},{"key":"10.3233\/CBM-160586_ref13","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1093\/aje\/kwu176","article-title":"Epstein-Barr Virus Antibodies and the Risk of Associated Malignancies: Review of the Literature","volume":"180","author":"Coghill","year":"2014","journal-title":"Am J Epidemiol"},{"key":"10.3233\/CBM-160586_ref14","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.otohns.2006.11.027","article-title":"Epstein-Barr virus DNA detection in the diagnosis of nasopharyngeal carcinoma","volume":"136","author":"Yap","year":"2007","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.3233\/CBM-160586_ref15","doi-asserted-by":"crossref","first-page":"e74853","DOI":"10.1371\/journal.pone.0074853","article-title":"Lactate Dehydrogenase 5 expression in Non-Hodgkin Lymphoma Is Associated with the Induced Hypoxia Regulated Protein and Poor Prognosis","volume":"8","author":"Lu","year":"2013","journal-title":"PLos One"},{"key":"10.3233\/CBM-160586_ref17","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jviromet.2015.03.024","article-title":"Development of a time-resolved fluoroimmunoassay for Epstein - Barrvirus viral capsid antigen IgA antibody in human serum","volume":"222","author":"Liang","year":"2015","journal-title":"Journal of Virological Methods"},{"key":"10.3233\/CBM-160586_ref18","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.biochi.2014.09.002","article-title":"Sodium arsenite induces apoptosis and Epstein-Barr virus reactivation in lymphoblastoid cells","volume":"107","author":"Zebboudj","year":"2014","journal-title":"Biochimie"},{"key":"10.3233\/CBM-160586_ref19","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1586\/14789450.2014.897613","article-title":"Biomarker discovery of nasopharyngeal carcinoma by proteomics","volume":"11","author":"Xiao","year":"2014","journal-title":"Expert Rev Proteomics"},{"key":"10.3233\/CBM-160586_ref20","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1016\/S0140-6736(05)66698-6","article-title":"Nasopharyngeal carcinoma","volume":"365","author":"Wei","year":"2005","journal-title":"Lancet"},{"key":"10.3233\/CBM-160586_ref21","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1093\/carcin\/bgp135","article-title":"Decoy receptor 3, upregulated by Epstein-Barr virus latent membrane protein 1, enhances nasopharyngeal carcinoma cell migration and invasion","volume":"30","author":"Ho","year":"2009","journal-title":"Carcinogenesis"},{"key":"10.3233\/CBM-160586_ref22","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1002\/1097-0142(20011001)92:7<1872::AID-CNCR1704>3.0.CO;2-N","article-title":"Antibody response to Epstein-Barr virus Rta protein in patients with nasopharyngeal carcinoma: A new serologic parameter for diagnosis","volume":"92","author":"Feng","year":"2001","journal-title":"Cancer"},{"key":"10.3233\/CBM-160586_ref23","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1002\/ijc.26380","article-title":"Establishment of VCA and EBNA1 IgA-based combination by enzyme-linked immunosorbent assay as preferred screening method for nasopharyngeal carcinoma: a two-stage design with a preliminary performance study and a mass screening in southern China","volume":"131","author":"Liu","year":"2012","journal-title":"Int J Cancer"},{"key":"10.3233\/CBM-160586_ref24","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.3390\/v7052268","article-title":"Celecoxib Inhibits the Lytic Activation of Kaposi's Sarcoma- Associated Herpesvirus through Down-Regulation of Rta Expression by Inhibiting the Activation of p38 MAPK","volume":"7","author":"Chen","year":"2015","journal-title":"Viruses"},{"key":"10.3233\/CBM-160586_ref25","doi-asserted-by":"crossref","first-page":"e84919","DOI":"10.1371\/journal.pone.0084919","article-title":"Reactive oxygen species mediate Epstein- Barr virus reactivation by -methyl-N'-nitro-N-nitrosoguanidine","volume":"8","author":"Huang","year":"2013","journal-title":"PLoS One"},{"key":"10.3233\/CBM-160586_ref26","doi-asserted-by":"crossref","first-page":"2001","DOI":"10.7314\/APJCP.2014.15.5.2001","article-title":"Diagnostic Significance of Combined Detection of Epstein-Barr Virus Antibodies, VCA\/IgA, EA\/IgA, Rta\/IgG and EBNA1\/IgA for Nasopharyngeal Carcinoma","volume":"15","author":"Cai","year":"2014","journal-title":"Asian Pac J Cancer Prev"}],"container-title":["Cancer Biomarkers"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/CBM-160586","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:08:10Z","timestamp":1777385290000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/CBM-160586"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,30]]},"references-count":25,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3233\/cbm-160586","relation":{},"ISSN":["1574-0153","1875-8592"],"issn-type":[{"value":"1574-0153","type":"print"},{"value":"1875-8592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,30]]}}}