{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:56:37Z","timestamp":1791345397767,"version":"4.3.1"},"reference-count":38,"publisher":"SAGE Publications","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CBM"],"published-print":{"date-parts":[[2020,8,3]]},"DOI":"10.3233\/cbm-191311","type":"journal-article","created":{"date-parts":[[2020,6,16]],"date-time":"2020-06-16T13:44:19Z","timestamp":1592315059000},"page":"511-521","source":"Crossref","is-referenced-by-count":15,"title":["FOXD1, negatively regulated by miR-186, promotes the proliferation, metastasis and radioresistance of nasopharyngeal carcinoma cells"],"prefix":"10.1177","volume":"28","author":[{"given":"Yong","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"10.3233\/CBM-191311_ref1","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0140-6736(19)30956-0","article-title":"Nasopharyngeal carcinoma","volume":"394","author":"Chen","year":"2019","journal-title":"Lancet"},{"key":"10.3233\/CBM-191311_ref2","first-page":"1223","article-title":"miR495 enhances the efficacy of radiotherapy by targeting GRP78 to regulate EMT in nasopharyngeal carcinoma cells","volume":"40","author":"Feng","year":"2018","journal-title":"Oncol Rep"},{"key":"10.3233\/CBM-191311_ref3","doi-asserted-by":"crossref","unstructured":"G. Zhang, K. Zhang, C. Li, Y. Li, Z. Li, N. Li, Q. Zhou and L. Shen, Serum proteomics identify potential biomarkers for nasopharyngeal carcinoma sensitivity to radiotherapy, Biosci Rep 39 (2019).","DOI":"10.1042\/BSR20190027"},{"key":"10.3233\/CBM-191311_ref4","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1002\/cam4.2056","article-title":"SALL4 induces radioresistance in nasopharyngeal carcinoma via the ATM\/Chk2\/p53 pathway","volume":"8","author":"Nie","year":"2019","journal-title":"Cancer Med"},{"key":"10.3233\/CBM-191311_ref5","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1038\/kisup.2014.6","article-title":"The FOXD1 lineage of kidney perivascular cells and myofibroblasts: functions and responses to injury","volume":"4","author":"Gomez","year":"2014","journal-title":"Kidney Int Suppl (2011)"},{"key":"10.3233\/CBM-191311_ref6","first-page":"1522","article-title":"FOXD1 predicts prognosis of colorectal cancer patients and promotes colorectal cancer progression via the ERK 1\/2 pathway","volume":"10","author":"Pan","year":"2018","journal-title":"Am J Transl Res"},{"key":"10.3233\/CBM-191311_ref7","doi-asserted-by":"crossref","first-page":"2716","DOI":"10.1159\/000495962","article-title":"FOXD1 Promotes Cell Growth and Metastasis by Activation of Vimentin in NSCLC","volume":"51","author":"Li","year":"2018","journal-title":"Cell Physiol Biochem"},{"key":"10.3233\/CBM-191311_ref8","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.bbrc.2014.11.064","article-title":"FOXD1 promotes breast cancer proliferation and chemotherapeutic drug resistance by targeting p27","volume":"456","author":"Zhao","year":"2015","journal-title":"Biochem Biophys Res Commun"},{"key":"10.3233\/CBM-191311_ref9","doi-asserted-by":"crossref","first-page":"109133","DOI":"10.1016\/j.biopha.2019.109133","article-title":"SP1-mediated long noncoding RNA POU3F3 accelerates the cervical cancer through miR-127-5p\/FOXD1","volume":"117","author":"Chang","year":"2019","journal-title":"Biomed Pharmacother"},{"key":"10.3233\/CBM-191311_ref10","doi-asserted-by":"crossref","first-page":"7219","DOI":"10.1158\/0008-5472.CAN-15-2860","article-title":"FOXD1-ALDH1A3 signaling is a determinant for the self-renewal and tumorigenicity of mesenchymal glioma stem cells","volume":"76","author":"Cheng","year":"2016","journal-title":"Cancer Res"},{"key":"10.3233\/CBM-191311_ref11","doi-asserted-by":"crossref","unstructured":"J. Tao, H. Cong, H. Wang, D. Zhang, C. Liu, H. Chu, Q. Qing and K. Wang, MiR-30a-5p inhibits osteosarcoma cell proliferation and migration by targeting FOXD1, Biochem Biophys Res Commun 503 (2018), 1092\u20131097.","DOI":"10.1016\/j.bbrc.2018.06.121"},{"key":"10.3233\/CBM-191311_ref12","doi-asserted-by":"crossref","first-page":"9227","DOI":"10.1038\/s41598-018-27521-y","article-title":"Validation of miRNA prognostic power in hepatocellular carcinoma using expression data of independent datasets","volume":"8","author":"Nagy","year":"2018","journal-title":"Sci Rep"},{"key":"10.3233\/CBM-191311_ref13","doi-asserted-by":"crossref","first-page":"3161","DOI":"10.12659\/MSM.915624","article-title":"Improved radiotherapy sensitivity of nasopharyngeal carcinoma cells by miR-29-3p targeting COL1A1 3\u2019-UTR","volume":"25","author":"Guo","year":"2019","journal-title":"Med Sci Monit"},{"key":"10.3233\/CBM-191311_ref14","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1515\/cclm-2017-0046","article-title":"miRNA analysis in pancreatic cancer: the dartmouth experience","volume":"55","author":"Abreu","year":"2017","journal-title":"Clin Chem Lab Med"},{"key":"10.3233\/CBM-191311_ref15","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1002\/cam4.660","article-title":"MiR-24 enhances radiosensitivity in nasopharyngeal carcinoma by targeting SP1","volume":"5","author":"Kang","year":"2016","journal-title":"Cancer Med"},{"key":"10.3233\/CBM-191311_ref16","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s10529-016-2273-2","article-title":"MicroRNA-190b confers radio-sensitivity through negative regulation of Bcl-2 in gastric cancer cells","volume":"39","author":"Wang","year":"2017","journal-title":"Biotechnol Lett"},{"key":"10.3233\/CBM-191311_ref17","doi-asserted-by":"crossref","first-page":"842","DOI":"10.3349\/ymj.2019.60.9.842","article-title":"Long intergenic non-protein coding RNA 665 regulates viability, apoptosis, and autophagy via the MiR-186-5p\/MAP4K3 axis in hepatocellular carcinoma","volume":"60","author":"Shan","year":"2019","journal-title":"Yonsei Med J"},{"key":"10.3233\/CBM-191311_ref18","doi-asserted-by":"crossref","first-page":"23135","DOI":"10.1002\/jcp.28878","article-title":"miR-186 modulates hepatocellular carcinoma cell proliferation and mobility via targeting MCRS1-mediated wnt\/\u03b2-catenin signaling","volume":"234","author":"Wang","year":"2019","journal-title":"J Cell Physiol"},{"key":"10.3233\/CBM-191311_ref19","doi-asserted-by":"crossref","unstructured":"F. Du, T. Guo and C. Cao, Silencing of long noncoding RNA SNHG6 inhibits esophageal squamous cell carcinoma progression via miR-186-5p\/HIF1\u03b1 axis, Dig Dis Sci (2019).","DOI":"10.1007\/s10620-019-06012-8"},{"key":"10.3233\/CBM-191311_ref20","doi-asserted-by":"crossref","first-page":"5661","DOI":"10.2147\/OTT.S207810","article-title":"LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy","volume":"12","author":"Chu","year":"2019","journal-title":"Onco Targets Ther"},{"key":"10.3233\/CBM-191311_ref21","doi-asserted-by":"crossref","first-page":"5497467","DOI":"10.1155\/2019\/5497467","article-title":"IGF-1R inhibition suppresses cell proliferation and increases radiosensitivity in nasopharyngeal carcinoma cells","volume":"2019","author":"Wang","year":"2019","journal-title":"Mediators Inflamm"},{"key":"10.3233\/CBM-191311_ref22","first-page":"479","article-title":"Irradiation-induced dynamic changes of gene signatures reveal gain of metastatic ability in nasopharyngeal carcinoma","volume":"9","author":"Wang","year":"2019","journal-title":"Am J Cancer Res"},{"key":"10.3233\/CBM-191311_ref23","doi-asserted-by":"crossref","unstructured":"J. Sheng, L. Wang, Y. Han, W. Chen, H. Liu, M. Zhang, L. Deng and Y.N. Liu, Dual roles of protein as a template and a sulfur provider: a general approach to metal sulfides for efficient photothermal therapy of cancer, Small 14 (2018).","DOI":"10.1002\/smll.201702529"},{"key":"10.3233\/CBM-191311_ref24","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/nrg2523","article-title":"The evolution of Fox genes and their role in development and disease","volume":"10","author":"Hannenhalli","year":"2009","journal-title":"Nat Rev Genet"},{"key":"10.3233\/CBM-191311_ref25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/dbio.2002.0780","article-title":"Forkhead transcription factors: key players in development and metabolism","volume":"250","author":"Carlsson","year":"2002","journal-title":"Dev Biol"},{"key":"10.3233\/CBM-191311_ref26","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1586\/14737140.2014.940324","article-title":"Transcription factors as master regulator for cancer stemness: remove milk from fox","volume":"14","author":"Nakano","year":"2014","journal-title":"Expert Rev Anticancer Ther"},{"key":"10.3233\/CBM-191311_ref27","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/j.biopha.2018.04.190","article-title":"Forkhead box D1 promotes proliferation and suppresses apoptosis via regulating polo-like kinase 2 in colorectal cancer","volume":"103","author":"Han","year":"2018","journal-title":"Biomed Pharmacother"},{"key":"10.3233\/CBM-191311_ref28","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1038\/s41419-019-1431-6","article-title":"CXCL5 induces tumor angiogenesis via enhancing the expression of FOXD1 mediated by the AKT\/NF-\u03baB pathway in colorectal cancer","volume":"10","author":"Chen","year":"2019","journal-title":"Cell Death Dis"},{"key":"10.3233\/CBM-191311_ref29","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1002\/jcp.24808","article-title":"Gene expression changes in progression of cervical neoplasia revealed by microarray analysis of cervical neoplastic keratinocytes","volume":"230","author":"Rotondo","year":"2015","journal-title":"J Cell Physiol"},{"key":"10.3233\/CBM-191311_ref30","first-page":"1495","article-title":"Human FOX gene family (Review)","volume":"25","author":"Katoh","year":"2004","journal-title":"Int J Oncol"},{"key":"10.3233\/CBM-191311_ref31","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1111\/j.1464-410X.2009.08351.x","article-title":"Gene expression of forkhead transcription factors in the normal and diseased human prostate","volume":"103","author":"van der Heul-Nieuwenhuijsen","year":"2009","journal-title":"BJU Int"},{"key":"10.3233\/CBM-191311_ref32","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/nrg1379","article-title":"MicroRNAs: small RNAs with a big role in gene regulation","volume":"5","author":"He","year":"2004","journal-title":"Nat Rev Genet"},{"key":"10.3233\/CBM-191311_ref33","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.cell.2009.01.002","article-title":"MicroRNAs: target recognition and regulatory functions","volume":"136","author":"Bartel","year":"2009","journal-title":"Cell"},{"key":"10.3233\/CBM-191311_ref34","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1158\/1535-7163.MCT-17-0385","article-title":"MiR-125b increases nasopharyngeal carcinoma radioresistance by targeting A20\/NF-\u03baB signaling pathway","volume":"16","author":"Li","year":"2017","journal-title":"Mol Cancer Ther"},{"key":"10.3233\/CBM-191311_ref35","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.kjms.2017.05.015","article-title":"miR-206 enhances nasopharyngeal carcinoma radiosensitivity by targeting IGF1","volume":"33","author":"Wang","year":"2017","journal-title":"Kaohsiung J Med Sci"},{"key":"10.3233\/CBM-191311_ref36","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s12935-017-0389-7","article-title":"MiR-20a-5p promotes radio-resistance by targeting Rab27B in nasopharyngeal cancer cells","volume":"17","author":"Huang","year":"2017","journal-title":"Cancer Cell Int"},{"key":"10.3233\/CBM-191311_ref37","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/labinvest.2015.134","article-title":"microRNA-186 inhibits cell proliferation and induces apoptosis in human esophageal squamous cell carcinoma by targeting SKP2","volume":"96","author":"He","year":"2016","journal-title":"Lab Invest"},{"key":"10.3233\/CBM-191311_ref38","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1186\/s13000-015-0372-3","article-title":"MiR-186 suppresses the growth and metastasis of bladder cancer by targeting NSBP1","volume":"10","author":"Yao","year":"2015","journal-title":"Diagn Pathol"}],"container-title":["Cancer Biomarkers"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/CBM-191311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:07:40Z","timestamp":1777385260000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/CBM-191311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,3]]},"references-count":38,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3233\/cbm-191311","relation":{},"ISSN":["1875-8592","1574-0153"],"issn-type":[{"value":"1875-8592","type":"electronic"},{"value":"1574-0153","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8,3]]}}}