{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:23:28Z","timestamp":1777479808975,"version":"3.51.4"},"reference-count":49,"publisher":"SAGE Publications","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CBM"],"published-print":{"date-parts":[[2019,7,23]]},"DOI":"10.3233\/cbm-192437","type":"journal-article","created":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T10:40:52Z","timestamp":1562064052000},"page":"259-273","source":"Crossref","is-referenced-by-count":6,"title":["Expression and clinical significance of neuropilin-1 in Epstein-Barr virus-associated lymphomas"],"prefix":"10.1177","volume":"25","author":[{"given":"Yong-Yao","family":"Gu","sequence":"first","affiliation":[{"name":"Department of Pathology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China"},{"name":"Department of Pathology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China"},{"name":"Department of Pathology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun-Yao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pathology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan-Shan","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Pathology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pathology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen-Bo","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Pathology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Gang","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"10.3233\/CBM-192437_ref1","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.pop.2016.07.012","article-title":"Lymphoma","volume":"43","author":"Mugnaini","year":"2016","journal-title":"Prim Care"},{"key":"10.3233\/CBM-192437_ref2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3322\/caac.21387","article-title":"Cancer statistics, 2017","volume":"67","author":"Siegel","year":"2017","journal-title":"CA Cancer J Clin"},{"key":"10.3233\/CBM-192437_ref3","first-page":"1","article-title":"Targeting the B cell receptor pathway in non-Hodgkin lymphoma","author":"Valla","year":"2018","journal-title":"Expert Opin Investig Drugs"},{"key":"10.3233\/CBM-192437_ref4","first-page":"375","article-title":"The use of chimeric antigen receptor T cells in patients with non-Hodgkin lymphoma","volume":"16","author":"Lulla","year":"2018","journal-title":"Clin Adv Hematol Oncol"},{"key":"10.3233\/CBM-192437_ref5","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1111\/bjh.15419","article-title":"Epstein-Barr virus-positive follicular lymphoma","volume":"182","author":"Kurt","year":"2018","journal-title":"Br J Haematol"},{"key":"10.3233\/CBM-192437_ref6","doi-asserted-by":"crossref","first-page":"E163","DOI":"10.3390\/cancers10060163","article-title":"Epstein Barr virus-associated Hodgkin lymphoma","volume":"10","author":"Carbone","year":"2018","journal-title":"Cancers (Basel)"},{"key":"10.3233\/CBM-192437_ref7","doi-asserted-by":"crossref","first-page":"e01239","DOI":"10.1128\/JVI.00330-18","article-title":"Analysis of Epstein-Barr virus genomes and expression profiles in gastric adenocarcinoma","volume":"92","author":"Borozan","year":"2018","journal-title":"J Virol"},{"key":"10.3233\/CBM-192437_ref8","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1002\/jso.25022","article-title":"Clinicopathological and prognostic features of Epstein-Barr virus infection, microsatellite instability, and PD-L1 expression in gastric cancer","volume":"117","author":"Pereira","year":"2018","journal-title":"J Surg Oncol"},{"key":"10.3233\/CBM-192437_ref9","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/s41419-018-0662-2","article-title":"DNMT1 mediates metabolic reprogramming induced by Epstein-Barr virus latent membrane protein 1 and reversed by grifolin in nasopharyngeal carcinoma","volume":"9","author":"Luo","year":"2018","journal-title":"Cell Death Dis"},{"key":"10.3233\/CBM-192437_ref10","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.3389\/fmicb.2017.02302","article-title":"Characterization of a suppressive cis-acting element in the Epstein-Barr virus LMP1 promoter","volume":"8","author":"Yoshida","year":"2017","journal-title":"Front Microbiol"},{"key":"10.3233\/CBM-192437_ref11","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/s41389-017-0005-7","article-title":"Cadherin 6 is activated by Epstein-Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma","volume":"6","author":"Zuo","year":"2017","journal-title":"Oncogenesis"},{"key":"10.3233\/CBM-192437_ref12","doi-asserted-by":"crossref","first-page":"e00030","DOI":"10.1128\/mSphere.00030-18","article-title":"C-terminal farnesylation of UCH-L1 plays a role in transport of Epstein-Barr virus primary oncoprotein LMP1 to exosomes","volume":"3","author":"Kobayashi","year":"2018","journal-title":"mSphere"},{"key":"10.3233\/CBM-192437_ref13","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s12308-016-0273-8","article-title":"Secondary B-cell lymphoma associated with the Epstein-Barr virus in chronic lymphocytic leukemia patients","volume":"9","author":"Morscio","year":"2016","journal-title":"J Hematop"},{"key":"10.3233\/CBM-192437_ref14","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/j.prp.2018.05.022","article-title":"Extranodal NK\/T-cell lymphoma of the nasal cavity developed in a patient with intestinal Epstein-Barr virus-positive T\/NK-cell lymphoproliferative disorder","volume":"214","author":"Furuya","year":"2018","journal-title":"Pathol Res Pract"},{"key":"10.3233\/CBM-192437_ref15","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1002\/cam4.1311","article-title":"Antitumor effects of duvelisib on Epstein-Barr virus-associated lymphoma cells","volume":"7","author":"Kawada","year":"2018","journal-title":"Cancer Med"},{"key":"10.3233\/CBM-192437_ref16","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.ijpharm.2018.05.074","article-title":"Nrp-1 receptor targeting peptide-functionalized TPGS micellar nanosystems to deliver 10-hydroxycampothecin for enhanced cancer chemotherapy","volume":"547","author":"Mozhi","year":"2018","journal-title":"Int J Pharm"},{"key":"10.3233\/CBM-192437_ref17","doi-asserted-by":"crossref","first-page":"4711","DOI":"10.1038\/s41388-018-0290-4","article-title":"NRP-1 interacts with GIPC1 and alpha6\/beta4-integrins to increase YAP1\/Np63alpha-dependent epidermal cancer stem cell survival","volume":"37","author":"Grun","year":"2018","journal-title":"Oncogene"},{"key":"10.3233\/CBM-192437_ref18","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1002\/ijc.31329","article-title":"miRNA-124-3p\/neuropilin-1(NRP-1) axis plays an important role in mediating glioblastoma growth and angiogenesis","volume":"143","author":"Zhang","year":"2018","journal-title":"Int J Cancer"},{"key":"10.3233\/CBM-192437_ref19","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.intimp.2018.04.025","article-title":"New peptide MY1340 revert the inhibition effect of VEGF on dendritic cells differentiation and maturation via blocking VEGF-NRP-1 axis and inhibit tumor growth in vivo","volume":"60","author":"Mo","year":"2018","journal-title":"Int Immunopharmacol"},{"key":"10.3233\/CBM-192437_ref20","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.biopha.2018.05.064","article-title":"RNA binding protein Lin28B confers gastric cancer cells stemness via directly binding to NRP-1","volume":"104","author":"Wang","year":"2018","journal-title":"Biomed Pharmacother"},{"key":"10.3233\/CBM-192437_ref21","doi-asserted-by":"crossref","first-page":"13777","DOI":"10.1007\/s13277-016-5138-3","article-title":"Neuropilin-1 (NRP-1)\/GIPC1 pathway mediates glioma progression","volume":"37","author":"Zhang","year":"2016","journal-title":"Tumour Biol"},{"key":"10.3233\/CBM-192437_ref22","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s11523-016-0422-0","article-title":"Role of NRP-1 in VEGF-VEGFR2-independent tumorigenesis","volume":"11","author":"Hu","year":"2016","journal-title":"Target Oncol"},{"key":"10.3233\/CBM-192437_ref23","doi-asserted-by":"crossref","first-page":"7970","DOI":"10.18632\/oncotarget.6699","article-title":"Aberrant NRP-1 expression serves as predicator of metastatic endometrial and lung cancers","volume":"7","author":"Okon","year":"2016","journal-title":"Oncotarget"},{"key":"10.3233\/CBM-192437_ref24","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1186\/s12885-018-4446-y","article-title":"Neuropilin-1 promotes the oncogenic Tenascin-C\/integrin beta3 pathway and modulates chemoresistance in breast cancer cells","volume":"18","author":"Naik","year":"2018","journal-title":"BMC Cancer"},{"key":"10.3233\/CBM-192437_ref25","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1097\/PAI.0b013e318259852a","article-title":"Wilms\u2019 tumor gene 1: a possible new proangiogenic factor in Hodgkin lymphoma","volume":"21","author":"Vadasz","year":"2013","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"10.3233\/CBM-192437_ref26","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1182\/blood-2009-05-221275","article-title":"Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK\/T-cell lymphoma, nasal type","volume":"115","author":"Huang","year":"2010","journal-title":"Blood"},{"key":"10.3233\/CBM-192437_ref27","doi-asserted-by":"crossref","first-page":"6240","DOI":"10.1038\/ncomms7240","article-title":"Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells","volume":"6","author":"Wang","year":"2015","journal-title":"Nat Commun"},{"key":"10.3233\/CBM-192437_ref28","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.anndiagpath.2018.04.004","article-title":"Evaluation of cMET aberration by immunohistochemistry and fluorescence in situ hybridization (FISH) in triple negative breast cancers","volume":"35","author":"Wang","year":"2018","journal-title":"Ann Diagn Pathol"},{"key":"10.3233\/CBM-192437_ref29","doi-asserted-by":"crossref","first-page":"286","DOI":"10.4048\/jbc.2017.20.3.286","article-title":"NanoString nCounter(R) approach in breast cancer: a comparative analysis with quantitative real-time polymerase chain reaction, in situ hybridization, and immunohistochemistry","volume":"20","author":"Hyeon","year":"2017","journal-title":"J Breast Cancer"},{"key":"10.3233\/CBM-192437_ref30","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/s41698-017-0018-x","article-title":"EBV based cancer prevention and therapy in nasopharyngeal carcinoma","volume":"1","author":"Cao","year":"2017","journal-title":"NPJ Precis Oncol"},{"key":"10.3233\/CBM-192437_ref31","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.virusres.2018.04.009","article-title":"Conservation and polymorphism of EBV RPMS1 gene in EBV-associated tumors and healthy individuals from endemic and non-endemic nasopharyngeal carcinoma areas in China","volume":"250","author":"Wu","year":"2018","journal-title":"Virus Res"},{"key":"10.3233\/CBM-192437_ref32","first-page":"298","article-title":"The clinical significance of EBV DNA analysis in nasopharyngeal carcinoma screening","volume":"32","author":"Wang","year":"2018","journal-title":"Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery"},{"key":"10.3233\/CBM-192437_ref33","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1111\/den.13181","article-title":"Epstein-Barr virus positivity among surgically resected intramucosal gastric cancer","volume":"30","author":"Murai","year":"2018","journal-title":"Dig Endosc"},{"key":"10.3233\/CBM-192437_ref34","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ctrv.2018.03.006","article-title":"Outlooks on Epstein-Barr virus associated gastric cancer","volume":"66","author":"Naseem","year":"2018","journal-title":"Cancer Treat Rev"},{"key":"10.3233\/CBM-192437_ref35","first-page":"312","article-title":"NRP-1\/shRNA silencing suppresses nasopharyngeal carcinoma cell growth in vitro and in vivo","volume":"50","author":"Sun","year":"2015","journal-title":"Chin J Otorhinolaryngol Head Neck Surg"},{"key":"10.3233\/CBM-192437_ref36","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1007\/s00432-018-2667-8","article-title":"Role of the NRP-1-mediated VEGFR2-independent pathway on radiation sensitivity of non-small cell lung cancer cells","volume":"144","author":"Hu","year":"2018","journal-title":"J Cancer Res Clin Oncol"},{"key":"10.3233\/CBM-192437_ref37","doi-asserted-by":"crossref","first-page":"32449","DOI":"10.18632\/oncotarget.8719","article-title":"Necrosis-inducing peptide has the beneficial effect on killing tumor cells through neuropilin (NRP-1) targeting","volume":"7","author":"Kim","year":"2016","journal-title":"Oncotarget"},{"key":"10.3233\/CBM-192437_ref38","doi-asserted-by":"crossref","first-page":"5434","DOI":"10.2174\/1381612821666150917092658","article-title":"Neuropilin-1 (NRP-1) and magnetic nanoparticles, a potential combination for diagnosis and therapy of gliomas","volume":"21","author":"Chen","year":"2015","journal-title":"Curr Pharm Des"},{"key":"10.3233\/CBM-192437_ref39","first-page":"3105","article-title":"Relationship between mature T- and NK-cell lymphoma and Epstein-Barr virus infection in Guangxi","volume":"20","author":"Mo","year":"2012","journal-title":"Guangdong Medical Journal"},{"key":"10.3233\/CBM-192437_ref40","first-page":"825","article-title":"Expression of PDGFRA and CMYC in extranodal NK\/T cell lymphoma and related prognostic factors","volume":"45","author":"Chen","year":"2016","journal-title":"Chinese Journal of Pathology"},{"key":"10.3233\/CBM-192437_ref41","first-page":"1410","article-title":"Infection status and prognosis analysis of Epstein-Barr virus in patients with newly diagnosed Hodgkin\u2019s lymphoma","volume":"24","author":"Yin","year":"2016","journal-title":"J Exp Hematol"},{"key":"10.3233\/CBM-192437_ref42","doi-asserted-by":"crossref","first-page":"5608","DOI":"10.1038\/onc.2015.516","article-title":"A novel association of neuropilin-1 and MUC1 in pancreatic ductal adenocarcinoma: role in induction of VEGF signaling and angiogenesis","volume":"35","author":"Zhou","year":"2016","journal-title":"Oncogene"},{"key":"10.3233\/CBM-192437_ref43","doi-asserted-by":"crossref","first-page":"150","DOI":"10.3892\/etm.2012.803","article-title":"NRP-1 silencing suppresses hepatocellular carcinoma cell growth in vitro and in vivo","volume":"5","author":"Xu","year":"2013","journal-title":"Exp Ther Med"},{"key":"10.3233\/CBM-192437_ref44","first-page":"383","article-title":"Expression of VEGF and CXCR4 in diffuse large B-cell lymphoma and its clinical significance","volume":"21","author":"Guo","year":"2013","journal-title":"Journal of Experimental Hematology"},{"key":"10.3233\/CBM-192437_ref46","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jiac.2016.09.004","article-title":"Prognostic significance of Epstein-Barr virus (EBV) infection in Hodgkin lymphoma patients","volume":"23","author":"Myriam","year":"2017","journal-title":"J Infect Chemother"},{"key":"10.3233\/CBM-192437_ref47","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1097\/MPA.0000000000000117","article-title":"High neuropilin 1 expression was associated with angiogenesis and poor overall survival in resected pancreatic ductal adenocarcinoma","volume":"43","author":"Ben","year":"2014","journal-title":"Pancreas"},{"key":"10.3233\/CBM-192437_ref48","doi-asserted-by":"crossref","first-page":"3417","DOI":"10.1038\/onc.2016.482","article-title":"Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality","volume":"36","author":"Tse","year":"2017","journal-title":"Oncogene"},{"key":"10.3233\/CBM-192437_ref49","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/liv.13495","article-title":"Neuropilin-1 regulated by miR-320 contributes to the growth and metastasis of cholangiocarcinoma cells","volume":"38","author":"Zhu","year":"2018","journal-title":"Liver Int"},{"key":"10.3233\/CBM-192437_ref50","first-page":"2245","article-title":"Neuropilin-1 promotes primary liver cancer progression by potentiating the activity of hepatic stellate cells","volume":"15","author":"Xu","year":"2018","journal-title":"Oncol Lett"}],"container-title":["Cancer Biomarkers"],"original-title":[],"link":[{"URL":"https:\/\/content.iospress.com\/download?id=10.3233\/CBM-192437","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:07:03Z","timestamp":1777385223000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.3233\/CBM-192437"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,23]]},"references-count":49,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3233\/cbm-192437","relation":{},"ISSN":["1875-8592","1574-0153"],"issn-type":[{"value":"1875-8592","type":"electronic"},{"value":"1574-0153","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7,23]]}}}